Aggregatibacter Details: NCBI 416916, gram-negative or unknown [genus]

| Aggregatibacter| Aggregatibacter Norskov-Lauritsen and Kilian 2006

  1. Oral Pathogen: Aggregatibacter actinomycetemcomitans is considered an oral pathogen and is often associated with periodontal diseases. It can colonize the periodontal pockets around teeth and contribute to the development of periodontitis, a severe form of gum disease.

  2. Periodontal Diseases: Aggregatibacter actinomycetemcomitans has been implicated in various periodontal diseases, including aggressive periodontitis. In aggressive periodontitis, there is a rapid loss of supporting structures around the teeth, leading to tooth mobility and potential tooth loss.

  3. Endocarditis: While less common, Aggregatibacter actinomycetemcomitans has been associated with infective endocarditis, an infection of the heart valves. Individuals with pre-existing heart conditions may be at a higher risk.

  4. Systemic Health: The presence of periodontal pathogens, including Aggregatibacter actinomycetemcomitans, has been studied in relation to systemic health. Some studies have explored potential links between periodontal diseases and conditions such as cardiovascular disease and diabetes. However, the nature of these associations is complex and may involve various factors.

  5. Antibiotic Resistance: Some strains of Aggregatibacter actinomycetemcomitans may exhibit antibiotic resistance, which can impact treatment strategies for infections caused by this bacterium.

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Statistics NCBI Data Punk End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Aggregatibacter

Using Kaltoft-Moldrup Heuristic Using uploaded data for Aggregatibacter

Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)
LabKM LowKM Percentile LowKM HighKM Percentile HighLab LowLab HighMean MedianStandard DeviationBox Plot LowBox Plot High
* 1 0 %ile 4901 100 %ile 0 2019 246.9 30 904.3 2 96
biomesight 10 0 %ile 3120 98.1 %ile 0 2143 318.4 60 930.9 0 320
thorne 1 0 %ile 21417 100 %ile 0 9067 841.8 6 4196.7 0 24
thryve 15 8 %ile 4416 100 %ile 0 835 98.1 30 376.1 8 104
ubiome 18 0 %ile 18250 100 %ile 0 4976 802.4 135 2129.4 0 745
Lab Suggestions for Aggregatibacter
Aggregatibacter (NCBI 416916) per million
Low Boundary High Boundary Low Boundary %age High Boundary %age Lab Samples
2.2 7.68 0.0002 0.0008 Thorne (20/80%ile)
Statistic by Lab Source for Aggregatibacter
These desired values are reported from the lab reports
Lab Frequency Seen Average Standard Deviation Sample Count Lab Samples
AmericanGut 6.667 %   0.49 %  % 1.0 15
BiomeSight 25.422 %   0.034 %  0.122 % 723.0 2844
BiomeSightRdp 43.75 %   0.004 %  0.005 % 14.0 32
CerbaLab 66.667 %   0.001 %  0 % 2.0 3
CosmosId 9.375 %   0.017 %  0.027 % 3.0 32
custom 10.169 %   0.001 %  0.001 % 6.0 59
es-xenogene 3.448 %   0.009 %  % 1.0 29
Medivere 71.429 %   0.006 %  0.007 % 5.0 7
SequentiaBiotech 5.556 %   0.037 %  0.02 % 2.0 36
Thorne 72.941 %   0.037 %  0.272 % 62.0 85
Thryve 19.058 %   0.008 %  0.032 % 263.0 1380
uBiome 21.591 %   0.08 %  0.213 % 171.0 792

Symptoms Associated with Aggregatibacter From Citizen Science Studies

Click on Impact for information if high or low levels are causing the impact

MagnitudeImpactSymptom
1 Increases Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep)
1 Reduces General: Myalgia (pain)
1 Increases General: Headaches
1 Increases Neurological: Impairment of concentration
1 Increases Neurological: Disorientation
1 Reduces Neurological: Word-finding problems
1 Increases Neurological-Vision: inability to focus eye/vision
1 Increases Neurological-Vision: photophobia (Light Sensitivity)
1 Reduces Neurological-Audio: hypersensitivity to noise
1 Increases Autonomic Manifestations: Orthostatic intolerance
1 Increases Autonomic Manifestations: Postural orthostatic tachycardia syndrome (POTS)
1 Reduces Autonomic Manifestations: nausea
1 Increases Autonomic Manifestations: irritable bowel syndrome
1 Increases Autonomic Manifestations: urinary frequency dysfunction
1 Reduces Autonomic Manifestations: bladder dysfunction
1 Increases Autonomic Manifestations: palpitations
1 Reduces Autonomic Manifestations: exertional dyspnea
1 Reduces Post-exertional malaise: Rapid muscular fatigability,
1 Reduces Post-exertional malaise: Rapid cognitive fatigability,
1 Increases Neuroendocrine Manifestations: subnormal body temperature
1 Reduces Neuroendocrine Manifestations: cold extremities
1 Reduces Neuroendocrine Manifestations: intolerance of extremes of heat and cold
1 Reduces Neuroendocrine Manifestations: marked weight change
1 Increases Neuroendocrine Manifestations: abnormal appetite
1 Increases Neuroendocrine Manifestations: worsening of symptoms with stress.
1 Increases Immune Manifestations: tender lymph nodes
1 Reduces Immune Manifestations: recurrent flu-like symptoms
1 Reduces Immune Manifestations: medication sensitivities.
1 Increases Onset: Sudden
1 Increases Onset: Gradual
1 Reduces Infection: Lyme
1 Increases Infection: Mycoplasma
1 Reduces Comorbid: Multiple Chemical Sensitivity
1 Increases Comorbid: Hypothyroidism
1 Increases Neurological: Neuropathy
1 Increases Neurological: Myoclonic jerks or seizures
1 Increases Neuroendocrine Manifestations: Excessive adrenaline
1 Reduces Neuroendocrine Manifestations: Muscle weakness
1 Reduces Neurological: Cognitive/Sensory Overload
1 Reduces Neurological: Slowed speech
1 Increases Immune Manifestations: Bloating
1 Reduces Immune Manifestations: Diarrhea
1 Reduces Neuroendocrine Manifestations: Air Hunger
1 Increases Neurological: Difficulty reading
1 Increases Neurological: Joint hypermobility
1 Reduces Onset: less than 02 years since onset
1 Increases Onset: less than 04 years since onset
1 Reduces Onset: less than 16 years since onset
1 Increases Onset: less than 32 years since onset
1 Increases Neurological-Audio: Tinnitus (ringing in ear)
1 Reduces Neurological-Sleep: Sleep Apnea
1 Reduces Neurological: High degree of Empathy before onset
1 Reduces Neuroendocrine Manifestations: Dry Eye (Sicca or Sjogren Syndrome)
1 Increases Comorbid-Mouth: Dry Mouth
1 Reduces Infection: Parasite - Other
1 Increases Neurological-Vision: Blurred Vision
1 Increases Immune Manifestations: Thick blood / Hypercoagulation
1 Reduces Neurological-Sleep: Inability for deep (delta) sleep
1 Increases Comorbid-Mouth: Gingivits / Gum Disease
1 Increases Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndrome
1 Reduces Autonomic Manifestations: Cortisol disorders or irregularity
1 Increases Comorbid: Small intestinal bacterial overgrowth (SIBO)
1 Increases Comorbid: Restless Leg
1 Increases Asymptomatic: No Health Issues
1 Increases Comorbid: Histamine or Mast Cell issues
1 Increases Neurological: Executive Decision Making (Difficulty making)
1 Reduces Gender: Female
1 Increases Onset: 2010-2020
1 Reduces Onset: 2000-2010
1 Reduces Age: 10-20
1 Increases Age: 20-30
1 Reduces Sleep: Problems falling asleep
1 Reduces Sleep: Problems staying asleep
1 Increases Sleep: Waking up early in the morning (e.g. 3 AM)
1 Reduces Pain: Pain or aching in muscles
1 Reduces Pain: Joint pain
1 Increases Pain: Eye pain
1 Increases Pain: Aching of the eyes or behind the eyes
1 Reduces Pain: Myofascial pain
1 Reduces Neuroendocrine: Lost or gained weight without trying
1 Reduces Neuroendocrine: Feeling hot or cold for no reason
1 Increases Neuroendocrine: Temperature fluctuations throughout the day
1 Reduces Immune: Viral infections with prolonged recovery periods
1 Reduces Other: Sensitivity to mold
1 Reduces Autonomic: Nausea
1 Increases Autonomic: Dizziness or fainting
1 Increases Autonomic: Inability to tolerate an upright position
1 Increases Neurocognitive: Problems remembering things
1 Increases Neurocognitive: Difficulty paying attention for a long period of time
1 Increases Neurocognitive: Can only focus on one thing at a time
1 Increases Neurocognitive: Unable to focus vision and/or attention
1 Increases Neurocognitive: Absent-mindedness or forgetfulness
1 Reduces Post-exertional malaise: Next-day soreness after everyday activities
1 Increases Post-exertional malaise: Worsening of symptoms after mild physical activity
1 Increases Official Diagnosis: Autism
1 Increases Official Diagnosis: Chronic Fatigue Syndrome (CFS/ME)
1 Increases Official Diagnosis: Depression
1 Increases Official Diagnosis: Irritable Bowel Syndrome
1 Reduces Joint: Tenderness
1 Increases Immune Manifestations: Mucus in the stool
1 Increases Comorbid-Mouth: Mouth Sores
1 Reduces Immune Manifestations: Inflammation of skin, eyes or joints
1 Increases Neurocognitive: Brain Fog
1 Increases Neuroendocrine Manifestations: Painful menstrual periods
1 Increases Official Diagnosis: Fibromyalgia
1 Reduces Comorbid-Mouth: Ulcers (mouth)
1 Reduces Immune Manifestations: Inflammation (General)
1 Increases Comorbid: Carbohydrate intolerance
1 Reduces Immune: Chronic Sinusitis
1 Increases Autonomic: Ocassional Tachycardia (Rapid heart beat)
1 Increases Blood Type: O Positive
1 Increases Comorbid: Salicylate sensitive
1 Reduces General: Sinus issues with headaches
1 Reduces Comorbid: Mood Swings
1 Increases Comorbid: Constipation and Explosions (not diarrohea)
1 Reduces Comorbid: Constipation and Diarrohea (not explosions)
1 Reduces Official Diagnosis: Gastroesophageal reflux disease (GERD)
1 Reduces Comorbid: Panic Attacks
1 Increases DePaul University Fatigue Questionnaire : Racing heart
1 Increases DePaul University Fatigue Questionnaire : Shortness of breath
1 Reduces DePaul University Fatigue Questionnaire : Abdomen pain
1 Reduces DePaul University Fatigue Questionnaire : Poor Appetite
1 Increases DePaul University Fatigue Questionnaire : Dizziness
1 Reduces DePaul University Fatigue Questionnaire : Night sweats
1 Reduces DePaul University Fatigue Questionnaire : Tense muscles
1 Increases DePaul University Fatigue Questionnaire : Chilled or shivery
1 Increases DePaul University Fatigue Questionnaire : Feeling like you have a temperature
1 Increases DePaul University Fatigue Questionnaire : Temperature lower than normal
1 Increases DePaul University Fatigue Questionnaire : Tingling feeling
1 Reduces DePaul University Fatigue Questionnaire : Eye pain
1 Increases DePaul University Fatigue Questionnaire : Rash
1 Reduces DePaul University Fatigue Questionnaire : Allergies
1 Reduces DePaul University Fatigue Questionnaire : Chemical sensitivity
1 Reduces DePaul University Fatigue Questionnaire : Muscle weakness
1 Reduces DePaul University Fatigue Questionnaire : Difficulty falling asleep
1 Reduces DePaul University Fatigue Questionnaire : Absent-mindedness
1 Increases DePaul University Fatigue Questionnaire : Confusion/disorientation
1 Increases DePaul University Fatigue Questionnaire : Difficulty reasoning things out
1 Reduces DePaul University Fatigue Questionnaire : Difficulty finding the right word
1 Reduces DePaul University Fatigue Questionnaire : Need to have to focus on one thing at a time
1 Reduces DePaul University Fatigue Questionnaire : Trouble expressing thoughts
1 Reduces DePaul University Fatigue Questionnaire : Frequently get words or numbers in the wrong order
1 Reduces DePaul University Fatigue Questionnaire : Slow to react
1 Reduces DePaul University Fatigue Questionnaire : New trouble with math
1 Reduces DePaul University Fatigue Questionnaire : Concern with driving
1 Reduces DePaul University Fatigue Questionnaire : Anxiety/tension
1 Reduces DePaul University Fatigue Questionnaire : Does physical activity make you feel better
1 Reduces DePaul University Fatigue Questionnaire : Does physical activity make you feel worse
1 Increases DePaul University Fatigue Questionnaire : Sore Throat
1 Reduces DePaul University Fatigue Questionnaire : Muscle Pain (i.e., sensations of pain or aching in your muscles. This does not include weakness or pain in other areas such as joints)
1 Increases DePaul University Fatigue Questionnaire : Impaired Memory & concentration
1 Reduces DePaul University Fatigue Questionnaire : Nausea
1 Reduces DePaul University Fatigue Questionnaire : Headaches
1 Increases Condition: Post-Traumatic Stress Disorder
1 Increases Condition: Generalized anxiety disorder
1 Reduces Condition: ME/CFS with IBS
1 Reduces Physical: Tonsils removed
1 Reduces Physical: Amalgam fillings
1 Reduces Physical: Breastfed
1 Reduces Physical: Pets
1 Reduces Physical: Good Air Quality
1 Reduces Physical: Organic Diet
1 Reduces Physical: Work-Sitting
1 Increases Physical: Steps Per Day 2000-4000
1 Reduces Physical: Steps Per Day 4000-8000
1 Reduces Physical: Steps Per Day 8000-16000
1 Increases Neuroendocrine Manifestations: Poor gut motility
1 Reduces Autism: High Functioning
1 Reduces Official Diagnosis: Hypercholesterolemia (High Cholesterol)
1 Reduces Official Diagnosis: COVID19 (Long Hauler)
1 Reduces Immune Manifestations: Chronic Flatus / Flatulence / gas
1 Reduces Neurocognitive: Aphantasia ( inability to visualize mental images)
1 Increases Official Diagnosis: COVID19 (Fully Recovered)
1 Reduces General: Anhedonia (inability to feel pleasure)

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Foods Containing the Aggregatibacter bacteria

Data comes from FoodMicrobionet. For the meaning of weight, see that site. The bacteria does not need to be alive to have an effect.

Passito wine Weight: 0.06238 Mozzarella cheese Weight: 0.005761

I would like to know what can change the quality that I have

Data Contradictions β€” Limits of Certainity

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General Substance Specific Substance Effect
Antibiotics, Antivirals etc azithromycin,(antibiotic)s[CFS] 1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc ceftriaxone (antibiotic)s 1 Studies recorded. The consensus is Increases📓, Click for details.
Antibiotics, Antivirals etc clarithromycin (antibiotic)s[CFS] 1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc doxycycline (antibiotic)s[CFS] 2 Studies recorded. The consensus is Decreases👪📓, Click for details.
Antibiotics, Antivirals etc minocycline (antibiotic)s[CFS] 1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc penicillin-moxalactam (antibiotic)s 1 Studies recorded. The consensus is Increases📓, Click for details.
Antibiotics, Antivirals etc streptomycin (antibiotic)s 1 Studies recorded. The consensus is Increases📓, Click for details.
Antibiotics, Antivirals etc sulfonamide (antibiotic)s 1 Studies recorded. The consensus is Increases📓, Click for details.
Antibiotics, Antivirals etc tetracycline (antibiotic)s 1 Studies recorded. The consensus is Increases📓, Click for details.
Drug or "Non-drug" Methylene blue 1 Studies recorded. The consensus is Decreases👪, Click for details.
Food (excluding seasonings) ku ding cha tea 1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings) Umeboshi (Japanese Apricot or Prunus mume ) 2 Studies recorded. The consensus is Decreases👶👪, Click for details.
Herb or Spice berberine 1 Studies recorded. The consensus is Increases📓, Click for details.
Herb or Spice cinnamon (oil. spice) 1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice coriander oil 1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice garlic (allium sativum) 3 Studies recorded. The consensus is Decreases👶👪📓, Click for details.
Herb or Spice lavender 1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice lemongrass oil 1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice peppermint (spice, oil) 1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice Perilla frutescens(shiso) 1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice thyme (thymol, thyme oil) 2 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar mastic gum (prebiotic) 2 Studies recorded. The consensus is Decreases👶📓, Click for details.
Prescription - Other proton-pump inhibitors (prescription) 1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics bacillus subtilis natto (probiotics) 1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics bifidobacterium longum bb536 (probiotics) 1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics lactobacillus kefiri (NOT KEFIR) 1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics lactobacillus rhamnosus (probiotics) 1 Studies recorded. The consensus is Increases📓, Click for details.
Vitamins, Minerals and similar vitamin d 1 Studies recorded. The consensus is Decreases📓, Click for details.

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