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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomImpactPredictor of Bacteria Shift
Age: 50-60Worsen1.51
Age: 60-70Improves-0.09
Asymptomatic: Minor Health Issues (a few symptoms only)Worsen2.82
Autism: Official DiagnosisWorsen3.75
Autonomic Manifestations: Orthostatic intoleranceImproves-3.53
Autonomic: Graying or blacking out after standingImproves-1.76
Autonomic: Shortness of breathImproves-2.86
Blood Type: A PositiveWorsen1.76
Blood Type: O PositiveWorsen2.23
Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grindingWorsen2.91
Comorbid-Mouth: Dry MouthWorsen2.37
Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndromeWorsen3.63
Comorbid: Constipation and Explosions (not diarrohea)Worsen3.22
Comorbid: High AnxietyWorsen1.51
Comorbid: Histamine or Mast Cell issuesWorsen3.63
Comorbid: HypothyroidismWorsen2.91
Comorbid: Inflammatory bowel disease Improves-2.78
Comorbid: Snoring (NOT Sleep ApneaWorsen3
Condition: ME/CFS with IBSWorsen3.01
DePaul University Fatigue Questionnaire : FatigueImproves-2.52
DePaul University Fatigue Questionnaire : Forgetting what you are trying to sayWorsen2.88
DePaul University Fatigue Questionnaire : Impaired Memory & concentrationImproves-2.49
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired Worsen2.01
General: FatigueImproves-2.79
General: Myalgia (pain)Improves-1.36
General: Sinus issues with headachesWorsen3.01
Immune Manifestations: Alcohol IntolerantWorsen2.91
Immune Manifestations: medication sensitivities.Improves-2.48
Immune: Tender / sore lymph nodesWorsen2.88
Infection: Human Herpesvirus 6 (HHV6)Worsen3.14
Infection: MycoplasmaWorsen2.91
Infection: Parasite - OtherWorsen3.63
Joint: RednessImproves-2.82
Joint: Stiffness and swellingWorsen2.81
Joint: TendernessImproves-2.7
Neurocognitive: Can only focus on one thing at a timeWorsen3.47
Neurocognitive: Unable to focus vision and/or attentionWorsen3.63
Neuroendocrine Manifestations: intolerance of extremes of heat and coldWorsen1.58
Neuroendocrine Manifestations: recurrent feelings of feverishnessImproves-2.79
Neuroendocrine Manifestations: worsening of symptoms with stress.Worsen3.47
Neuroendocrine: Alcohol intoleranceWorsen4.23
Neuroendocrine: Feeling like you have a low temperatureWorsen2.74
Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep)Improves-2.92
Neurological-Sleep: InsomniaImproves-2.92
Neurological-Vision: inability to focus eye/visionWorsen3.01
Neurological-Vision: photophobia (Light Sensitivity)Worsen3.63
Neurological: Cognitive/Sensory OverloadImproves-2.26
Neurological: Difficulty readingWorsen2.91
Neurological: emotional overloadWorsen2.74
Neurological: fasciculations Worsen2.74
Neurological: High degree of Empathy before onsetWorsen2.74
Neurological: Joint hypermobilityImproves-2.82
Neurological: Short-term memory issuesWorsen2.47
Neurological: Spatial instability and disorientationWorsen2.74
Official Diagnosis: Allergic Rhinitis (Hay Fever)Worsen3.29
Official Diagnosis: Autoimmune DiseaseImproves-2.92
Official Diagnosis: Irritable Bowel SyndromeImproves-2.92
Official Diagnosis: Mast Cell DysfunctionWorsen3
Onset: GradualImproves-1.95
Pain: Sensitivity to painWorsen2.91
Post-exertional malaise: Difficulty reading after mild physical or mental activityWorsen3.98
Post-exertional malaise: GeneralWorsen2.74
Post-exertional malaise: Mentally tired after the slightest effortWorsen3.33
Post-exertional malaise: Physically drained or sick after mild activityWorsen2.74
Post-exertional malaise: Post-exertional malaiseWorsen2.74
Post-exertional malaise: Rapid cognitive fatigability, Worsen2.74
Post-exertional malaise: Rapid muscular fatigability, Worsen1.63
Post-exertional malaise: Worsening of symptoms after mild mental activityWorsen2.74
Sleep: Need to nap dailyWorsen2.52
Sleep: Waking up early in the morning (e.g. 3 AM)Worsen2.91

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomImpactPredictor of Bacteria Shift
AcneImproves-3.47
ADHDWorsen2.88
AllergiesWorsen0.3
Alzheimer's diseaseImproves-4.05
Amyotrophic lateral sclerosis (ALS) Motor NeuronWorsen2.74
Ankylosing spondylitisWorsen3.53
AsthmaWorsen3.48
AtherosclerosisImproves-4.51
AutismImproves-4.68
Barrett esophagus cancerWorsen1.46
Brain TraumaImproves-3.96
CarcinomaWorsen0
Celiac DiseaseImproves-2.88
Chronic Fatigue SyndromeImproves-4.81
Chronic Kidney DiseaseImproves-3.68
Chronic urticaria (Hives)Improves-1.63
Colorectal CancerWorsen2.36
Coronary artery disease Improves-3.27
Crohn's DiseaseWorsen2.56
DepressionWorsen3.02
EpilepsyImproves-3.47
FibromyalgiaImproves-3.41
Functional constipation / chronic idiopathic constipationImproves-3.01
Gastroesophageal reflux disease (Gerd) including Barrett's esophagusImproves-1.46
Graves' diseaseWorsen2.74
Hashimoto's thyroiditisWorsen2.99
High Blood PressureImproves-3.72
Histamine IssuesWorsen1.21
Histamine Issues From UbiomeImproves-2.72
Hyperlipidemia (High Blood Fats)Worsen1.3
IgA nephropathy (IgAN)Improves-3.9
Inflammatory Bowel DiseaseImproves-3.87
InsomniaImproves-2.31
Irritable Bowel SyndromeImproves-4.86
Liver CirrhosisImproves-4.98
ME/CFS with IBSImproves-3.78
ME/CFS without IBSImproves-2.88
Mood DisordersImproves-2.74
Multiple SclerosisWorsen2.06
Multiple system atrophy (MSA)Worsen2.52
Nonalcoholic Fatty Liver Disease (nafld) NonalcoholicImproves-3.57
ObesityImproves-2.23
OsteoporosisWorsen2.72
Parkinson's DiseaseImproves-2.18
PsoriasisWorsen2.88
Rheumatoid arthritisImproves-3.93
rheumatoid arthritis (RA),Spondyloarthritis (SpA)Worsen2.54
RosaceaImproves-1.97
SchizophreniaWorsen4.26
Sjögren syndromeImproves-2.88
Stress / posttraumatic stress disorderImproves-2.77
Systemic Lupus ErythematosusWorsen1.46
Type 1 DiabetesImproves-3.97
Type 2 DiabetesImproves-0.76
Ulcerative colitisWorsen1.91

Bacteria Impacted

Suggest a missed study:

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Enterobacteriaceae family Decreases 📓 Source Study
Clostridiales Family XIII. Incertae Sedis family Increases 👶 Source Study
Clostridiales Family XIII. Incertae Sedis family Increases 📓 Source Study
Eubacteriaceae family Increases 📓 Source Study
Lachnospiraceae family Increases 📓 Source Study
Citrobacter genus Decreases 📓 Source Study
Atlantibacter genus Decreases 👪 Source Study
Biostraticola genus Decreases 👪 Source Study
Buttiauxella genus Decreases 👪 Source Study
Candidatus Ishikawaella genus Decreases 👪 Source Study
Cedecea genus Decreases 👪 Source Study
Gibbsiella genus Decreases 👪 Source Study
Kosakonia genus Decreases 👪 Source Study
Leclercia genus Decreases 👪 Source Study
Lelliottia genus Decreases 👪 Source Study
Limnobaculum genus Decreases 👪 Source Study
Metakosakonia genus Decreases 👪 Source Study
Moranella genus Decreases 👪 Source Study
Pluralibacter genus Decreases 👪 Source Study
Pseudescherichia genus Decreases 👪 Source Study
Raoultella genus Decreases 👪 Source Study
Riesia genus Decreases 👪 Source Study
Rosenbergiella genus Decreases 👪 Source Study
Shimwellia genus Decreases 👪 Source Study
Siccibacter genus Decreases 👪 Source Study
Yokenella genus Decreases 👪 Source Study
Acetatifactor genus Increases 👪 Source Study
Acetitomaculum genus Increases 👪 Source Study
Acetobacterium genus Increases 👪 Source Study
Agathobacter genus Increases 👪 Source Study
Alkalibacter genus Increases 👪 Source Study
Alkalibaculum genus Increases 👪 Source Study
Aminicella genus Increases 👪 Source Study
Aminipila genus Increases 👪 Source Study
Anaerobium genus Increases 👪 Source Study
Anaerobutyricum genus Increases 👪 Source Study
Anaerocolumna genus Increases 👪 Source Study
Anaerofustis genus Increases 👪 Source Study
Anaerosporobacter genus Increases 👪 Source Study
Anaerotaenia genus Increases 👪 Source Study
Anaerotignum genus Increases 👪 Source Study
Anaerovorax genus Increases 👪 Source Study
Casaltella genus Increases 👪 Source Study
Catonella genus Increases 👪 Source Study
Cellulosilyticum genus Increases 👪 Source Study
Eisenbergiella genus Increases 👪 Source Study
Emergencia genus Increases 👪 Source Study
Faecalicatena Sakamoto et al. 2017 genus Increases 👪 Source Study
Fusicatenibacter genus Increases 👪 Source Study
Herbinix genus Increases 👪 Source Study
Hespellia genus Increases 👪 Source Study
Ihubacter genus Increases 👪 Source Study
Ileibacterium genus Increases 👪 Source Study
Intestinibacillus genus Increases 👪 Source Study
Johnsonella genus Increases 👪 Source Study
Lachnoanaerobaculum genus Increases 👪 Source Study
Lachnobacterium genus Increases 👪 Source Study
Lachnotalea genus Increases 👪 Source Study
Merdimonas genus Increases 👪 Source Study
Mobilitalea genus Increases 👪 Source Study
Mogibacterium genus Increases 👪 Source Study
Moryella genus Increases 👪 Source Study
Murimonas genus Increases 👪 Source Study
Oribacterium genus Increases 👪 Source Study
Parasporobacterium genus Increases 👪 Source Study
Pseudoramibacter genus Increases 👪 Source Study
Robinsoniella genus Increases 👪 Source Study
Sellimonas genus Increases 👪 Source Study
Shuttleworthia genus Increases 👪 Source Study
Sporobacterium genus Increases 👪 Source Study
Stomatobaculum genus Increases 👪 Source Study
Syntrophococcus genus Increases 👪 Source Study
Tyzzerella genus Increases 👪 Source Study
Agathobaculum genus Increases 👶 Source Study
Anaerobutyricum genus Increases 👶 Source Study
Agathobaculum genus Increases 📓 Source Study
Anaerobutyricum genus Increases 📓 Source Study
Bifidobacterium genus Increases 📓 Source Study
Bifidobacterium genus Increases 📓 Source Study
Eubacterium genus Increases 📓 Source Study
Lactobacillus genus Increases 📓 Source Study
Lactobacillus genus Increases 📓 Source Study
Roseburia genus Increases 📓 Source Study
ATCC 51112 species Decreases 👪 Source Study
Citrobacter amalonaticus species Decreases 👪 Source Study
Citrobacter sp. species Decreases 👪 Source Study
Citrobacter sp. BW4 species Decreases 👪 Source Study
Citrobacter sp. HD4.9 species Decreases 👪 Source Study
JCM 1658 species Decreases 👪 Source Study
[Eubacterium] brachy species Increases 👪 Source Study
[Eubacterium] cellulosolvens species Increases 👪 Source Study
[Eubacterium] eligens species Increases 👪 Source Study
[Eubacterium] hallii species Increases 👪 Source Study
[Eubacterium] infirmum species Increases 👪 Source Study
[Eubacterium] minutum species Increases 👪 Source Study
[Eubacterium] nodatum species Increases 👪 Source Study
[Eubacterium] saphenum species Increases 👪 Source Study
[Eubacterium] sulci species Increases 👪 Source Study
Agathobaculum butyriciproducens species Increases 👪 Source Study
ATCC 25258 species Increases 👪 Source Study
ATCC 33199 species Increases 👪 Source Study
ATCC 35046 species Increases 👪 Source Study
ATCC 49062 species Increases 👪 Source Study
ATCC 49165 species Increases 👪 Source Study
ATCC 700211 species Increases 👪 Source Study
ATCC 700308 species Increases 👪 Source Study
ATCC 700934 species Increases 👪 Source Study
ATCC 8041 species Increases 👪 Source Study
BCRC 17755 species Increases 👪 Source Study
Bifidobacterium actinocoloniiforme species Increases 👪 Source Study
Bifidobacterium angulatum species Increases 👪 Source Study
Bifidobacterium avesanii species Increases 👪 Source Study
Bifidobacterium cuniculi species Increases 👪 Source Study
Bifidobacterium lemurum species Increases 👪 Source Study
Bifidobacterium sp. 113 species Increases 👪 Source Study
Bifidobacterium sp. group II-3 species Increases 👪 Source Study
Bifidobacterium sp. h12 species Increases 👪 Source Study
Bifidobacterium sp. JCM 6439 species Increases 👪 Source Study
Bifidobacterium sp. M45 species Increases 👪 Source Study
Bifidobacterium sp. MC_8 species Increases 👪 Source Study
Bifidobacterium sp. PL1 species Increases 👪 Source Study
CCTCC M 2011381 species Increases 👪 Source Study
CCUG 48456 species Increases 👪 Source Study
CCUG 48460 species Increases 👪 Source Study
CCUG 53174 species Increases 👪 Source Study
CCUG 63301 species Increases 👪 Source Study
CCUG 63631 species Increases 👪 Source Study
CIP 106922 species Increases 👪 Source Study
CRBIP 24.179 species Increases 👪 Source Study
DSM 16230 species Increases 👪 Source Study
DSM 19284 species Increases 👪 Source Study
DSM 19907 species Increases 👪 Source Study
DSM 24301 species Increases 👪 Source Study
DSM 26202 species Increases 👪 Source Study
DSM 28069 species Increases 👪 Source Study
environmental samples species Increases 👪 Source Study
Eubacterium coprostanoligenes species Increases 👪 Source Study
Eubacterium desmolans species Increases 👪 Source Study
Eubacterium limosum species Increases 👪 Source Study
Eubacterium oxidoreducens species Increases 👪 Source Study
Eubacterium pyruvativorans species Increases 👪 Source Study
Eubacterium ramulus species Increases 👪 Source Study
Eubacterium rangiferina species Increases 👪 Source Study
Eubacterium ruminantium species Increases 👪 Source Study
Eubacterium sp. species Increases 👪 Source Study
Eubacterium sp. ARC-2 species Increases 👪 Source Study
Eubacterium sp. oral clone BU014 species Increases 👪 Source Study
Eubacterium sp. oral strain A35MT species Increases 👪 Source Study
Eubacterium sp. SA11 species Increases 👪 Source Study
Eubacterium uniforme species Increases 👪 Source Study
Eubacterium ventriosum species Increases 👪 Source Study
Eubacterium xylanophilum species Increases 👪 Source Study
JCM 1039 species Increases 👪 Source Study
JCM 11969 species Increases 👪 Source Study
JCM 18665 species Increases 👪 Source Study
JCM 31938 species Increases 👪 Source Study
JCM 32269 species Increases 👪 Source Study
Lactobacillus acetotolerans species Increases 👪 Source Study
Lactobacillus acidipiscis species Increases 👪 Source Study
Lactobacillus agilis species Increases 👪 Source Study
Lactobacillus alimentarius species Increases 👪 Source Study
Lactobacillus amylolyticus species Increases 👪 Source Study
Lactobacillus apis species Increases 👪 Source Study
Lactobacillus bifermentans species Increases 👪 Source Study
Lactobacillus bombi species Increases 👪 Source Study
Lactobacillus brantae species Increases 👪 Source Study
Lactobacillus ceti species Increases 👪 Source Study
Lactobacillus coleohominis species Increases 👪 Source Study
Lactobacillus composti species Increases 👪 Source Study
Lactobacillus coryniformis species Increases 👪 Source Study
Lactobacillus equi species Increases 👪 Source Study
Lactobacillus equigenerosi species Increases 👪 Source Study
Lactobacillus fermentum species Increases 👪 Source Study
Lactobacillus floricola species Increases 👪 Source Study
Lactobacillus fuchuensis species Increases 👪 Source Study
Lactobacillus hamsteri species Increases 👪 Source Study
Lactobacillus harbinensis species Increases 👪 Source Study
Lactobacillus hayakitensis species Increases 👪 Source Study
Lactobacillus helveticus species Increases 👪 Source Study
Lactobacillus hilgardii species Increases 👪 Source Study
Lactobacillus ingluviei species Increases 👪 Source Study
Lactobacillus intestinalis species Increases 👪 Source Study
Lactobacillus johnsonii species Increases 👪 Source Study
Lactobacillus kalixensis species Increases 👪 Source Study
Lactobacillus kefiranofaciens species Increases 👪 Source Study
lactobacillus kefiri species Increases 👪 Source Study
Lactobacillus lindneri species Increases 👪 Source Study
Lactobacillus malefermentans species Increases 👪 Source Study
Lactobacillus mellifer species Increases 👪 Source Study
Lactobacillus mellis species Increases 👪 Source Study
Lactobacillus murinus species Increases 👪 Source Study
Lactobacillus namurensis species Increases 👪 Source Study
Lactobacillus nodensis species Increases 👪 Source Study
Lactobacillus oligofermentans species Increases 👪 Source Study
Lactobacillus oryzae species Increases 👪 Source Study
Lactobacillus ozensis species Increases 👪 Source Study
Lactobacillus pantheris species Increases 👪 Source Study
Lactobacillus parabuchneri species Increases 👪 Source Study
Lactobacillus parafarraginis species Increases 👪 Source Study
Lactobacillus paralimentarius species Increases 👪 Source Study
Lactobacillus perolens species Increases 👪 Source Study
Lactobacillus plajomi species Increases 👪 Source Study
Lactobacillus pontis species Increases 👪 Source Study
Lactobacillus psittaci species Increases 👪 Source Study
Lactobacillus rodentium species Increases 👪 Source Study
Lactobacillus sakei species Increases 👪 Source Study
Lactobacillus selangorensis species Increases 👪 Source Study
Lactobacillus songhuajiangensis species Increases 👪 Source Study
Lactobacillus sp. species Increases 👪 Source Study
Lactobacillus sp. 7_1_47FAA species Increases 👪 Source Study
Lactobacillus sp. Akhmro1 species Increases 👪 Source Study
Lactobacillus sp. BHWM-4 species Increases 👪 Source Study
Lactobacillus sp. C30An8 species Increases 👪 Source Study
Lactobacillus sp. C4I1 species Increases 👪 Source Study
Lactobacillus sp. C4I18 species Increases 👪 Source Study
Lactobacillus sp. CBA3606 species Increases 👪 Source Study
Lactobacillus sp. H7_2_4MCO2 species Increases 👪 Source Study
Lactobacillus sp. H7_6_6MCO2 species Increases 👪 Source Study
Lactobacillus sp. HBUAS52074 species Increases 👪 Source Study
Lactobacillus sp. HSLZ-75 species Increases 👪 Source Study
Lactobacillus sp. MYMRS/TEN2 species Increases 👪 Source Study
Lactobacillus sp. NRCT-KU 1 species Increases 👪 Source Study
Lactobacillus sp. S16 species Increases 👪 Source Study
Lactobacillus sp. T059 species Increases 👪 Source Study
Lactobacillus sp. TAB-22 species Increases 👪 Source Study
Lactobacillus sp. TAB-29 species Increases 👪 Source Study
Lactobacillus tucceti species Increases 👪 Source Study
Lactobacillus vaccinostercus species Increases 👪 Source Study
Lactobacillus vaginalis species Increases 👪 Source Study
Lactobacillus vini species Increases 👪 Source Study
Lactobacillus yamanashiensis species Increases 👪 Source Study
Lactobacillus zymae species Increases 👪 Source Study
Lactobacterium buchneri species Increases 👪 Source Study
LMG:9200 species Increases 👪 Source Study
LMG:9496 species Increases 👪 Source Study
not JCM 16719 species Increases 👪 Source Study
Roseburia sp. species Increases 👪 Source Study
Roseburia sp. 1120 species Increases 👪 Source Study
Roseburia sp. 11SE38 species Increases 👪 Source Study
Roseburia sp. 499 species Increases 👪 Source Study
Roseburia sp. DJF_VR77 species Increases 👪 Source Study
Roseburia sp. MC_37 species Increases 👪 Source Study
[Eubacterium] brachy species Increases 📓 Source Study
[Eubacterium] cellulosolvens species Increases 📓 Source Study
[Eubacterium] eligens species Increases 📓 Source Study
[Eubacterium] hallii species Increases 📓 Source Study
[Eubacterium] saphenum species Increases 📓 Source Study
ATCC 49165 species Increases 📓 Source Study
environmental samples species Increases 📓 Source Study
Eubacterium coprostanoligenes species Increases 📓 Source Study
Eubacterium desmolans species Increases 📓 Source Study
Eubacterium limosum species Increases 📓 Source Study
Eubacterium oxidoreducens species Increases 📓 Source Study
Eubacterium pyruvativorans species Increases 📓 Source Study
Eubacterium ramulus species Increases 📓 Source Study
Eubacterium ruminantium species Increases 📓 Source Study
Eubacterium sp. ARC-2 species Increases 📓 Source Study
Eubacterium sp. SA11 species Increases 📓 Source Study
Eubacterium uniforme species Increases 📓 Source Study
Eubacterium ventriosum species Increases 📓 Source Study
Eubacterium xylanophilum species Increases 📓 Source Study
Roseburia cecicola species Increases 📓 Source Study
Roseburia faecis species Increases 📓 Source Study
Roseburia hominis species Increases 📓 Source Study
Roseburia intestinalis species Increases 📓 Source Study
Roseburia inulinivorans species Increases 📓 Source Study
Roseburia sp. 11SE38 species Increases 📓 Source Study
Roseburia sp. 11SE39 species Increases 📓 Source Study
Roseburia sp. 499 species Increases 📓 Source Study
Roseburia sp. DJF_RR73 species Increases 📓 Source Study

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