fluoroquinolone (antibiotic)s ** full range

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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

Symptom	Impact	Predictor of Bacteria Shift
Age: 20-30	Worsen	2.76
Autonomic Manifestations: cardiac arrhythmias	Worsen	2.83
Comorbid: Fibromyalgia	Improves	-2.96
DePaul University Fatigue Questionnaire : Difficulty staying asleep	Improves	-2.83
Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin)	Worsen	2.43
Neuroendocrine: Feeling like you have a low temperature	Improves	-2.74
Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep)	Worsen	2.43
Neurological-Vision: inability to focus eye/vision	Worsen	2.43
Neurological-Vision: photophobia (Light Sensitivity)	Worsen	2.43
Neurological: Difficulty reading	Worsen	2.43
Neurological: emotional overload	Improves	-2.74
Neurological: Executive Decision Making (Difficulty making)	Worsen	2.42
Neurological: fasciculations	Improves	-2.74
Neurological: High degree of Empathy before onset	Improves	-2.74
Neurological: Impairment of concentration	Worsen	2.42
Neurological: Short-term memory issues	Improves	-2.74
Neurological: Slowed speech	Worsen	2.76
Neurological: Spatial instability and disorientation	Improves	-2.74
Onset: Gradual	Worsen	2.63
Onset: less than 02 years since onset	Improves	-2.74
Pain: Sensitivity to pain	Improves	-1.71
Post-exertional malaise: Worsening of symptoms after mild mental activity	Improves	-2.74

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

Symptom	Impact	Predictor of Bacteria Shift
Acne	Improves	-3.3
ADHD	Improves	-2.48
Allergic Rhinitis (Hay Fever)	Improves	-3.25
Allergies	Improves	-2.93
Alzheimer's disease	Improves	-2.04
Amyotrophic lateral sclerosis (ALS) Motor Neuron	Improves	-2.97
Ankylosing spondylitis	Improves	-3.85
Asthma	Worsen	2.21
Atherosclerosis	Improves	-4.48
Autism	Worsen	5.16
Autoimmune Disease	Improves	-1.28
Barrett esophagus cancer	Worsen	1.8
Bipolar Disorder	Improves	-3.48
Brain Trauma	Worsen	3.38
Carcinoma	Improves	-4.4
Celiac Disease	Improves	-3.15
Cerebral Palsy	Improves	-2.83
Chronic Fatigue Syndrome	Improves	-1.39
Chronic Kidney Disease	Improves	-3.25
Chronic Lyme	Worsen	2.74
Chronic Urticaria (Hives)	Improves	-1.88
Colorectal Cancer	Improves	-5.42
Coronary artery disease	Improves	-3.36
COVID-19	Improves	-2.93
Crohn's Disease	Improves	-2.15
cystic fibrosis	Improves	-3.79
Depression	Worsen	2.01
Epilepsy	Improves	-0.79
Fibromyalgia	Worsen	3.17
Functional constipation / chronic idiopathic constipation	Worsen	1.09
gallstone disease (gsd)	Worsen	2.48
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus	Worsen	2.77
Generalized anxiety disorder	Improves	-3.69
Graves' disease	Improves	-3.88
Hashimoto's thyroiditis	Worsen	1.72
High Blood Pressure	Worsen	3.57
Histamine Issues	Improves	-4.64
hypercholesterolemia (High Cholesterol)	Worsen	2.13
IgA nephropathy (IgAN)	Worsen	3.41
Inflammatory Bowel Disease	Improves	-5.12
Insomnia	Worsen	2.76
Irritable Bowel Syndrome	Improves	-4.38
Liver Cirrhosis	Improves	-5.61
ME/CFS with IBS	Improves	-3.5
ME/CFS without IBS	Improves	-3.36
Mood Disorders	Worsen	2.74
Multiple Sclerosis	Improves	-2.84
neuropsychiatric disorders (PANDAS, PANS)	Improves	-2.42
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic	Improves	-3.82
Obesity	Improves	-3.98
Osteoarthritis	Improves	-3.3
Osteoporosis	Improves	-2.41
Parkinson's Disease	Worsen	4.91
Psoriasis	Improves	-4.54
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	Improves	-5.12
Rosacea	Worsen	2.9
Schizophrenia	Improves	-3.54
Sjögren syndrome	Improves	-4.47
Small Intestinal Bacterial Overgrowth (SIBO)	Improves	-4.8
Stress / posttraumatic stress disorder	Improves	-4.53
Systemic Lupus Erythematosus	Improves	-4.1
Type 1 Diabetes	Worsen	4.01
Type 2 Diabetes	Improves	-2.49
Ulcerative colitis	Improves	-4.67

Bacteria Impacted

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.