foeniculum vulgare (Fennel) ** full range

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Fennel, bulb, raw flavonoids and polyphenols

Fennel, leaves, raw flavonoids and polyphenols

Fennel flavonoids and polyphenols

Fennel, dried flavonoids and polyphenols

Fennel, fresh leaves flavonoids and polyphenols

Fennel, tea flavonoids and polyphenols

Herb or Spice

Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

Symptom	Impact	Predictor of Bacteria Shift
Age: 20-30	Worsen	2.48
Comorbid-Mouth: Dry Mouth	Worsen	2.74
Comorbid-Mouth: Mouth Sores	Worsen	2.56
Comorbid: Constipation and Explosions (not diarrohea)	Worsen	2.56
Immune Manifestations: Abdominal Pain	Worsen	2.48
Neurocognitive: Slowness of thought	Worsen	2.48
Neurocognitive: Unable to focus vision and/or attention	Worsen	2.56
Neuroendocrine: Feeling like you have a low temperature	Worsen	2.74
Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep)	Worsen	2.56
Neurological-Vision: inability to focus eye/vision	Worsen	2.56
Neurological: Difficulty reading	Worsen	2.56
Neurological: emotional overload	Worsen	2.74
Neurological: Executive Decision Making (Difficulty making)	Worsen	2.42
Neurological: fasciculations	Worsen	2.74
Neurological: High degree of Empathy before onset	Worsen	2.74
Neurological: Short-term memory issues	Worsen	2.74
Neurological: Spatial instability and disorientation	Worsen	2.74
Post-exertional malaise: General	Worsen	2.74
Post-exertional malaise: Mentally tired after the slightest effort	Worsen	2.74
Post-exertional malaise: Physically drained or sick after mild activity	Worsen	2.74
Post-exertional malaise: Post-exertional malaise	Worsen	2.74
Post-exertional malaise: Rapid cognitive fatigability,	Worsen	2.74
Post-exertional malaise: Worsening of symptoms after mild mental activity	Worsen	2.74

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

Symptom	Impact	Predictor of Bacteria Shift
Allergies	Worsen	2.61
Amyotrophic lateral sclerosis (ALS) Motor Neuron	Worsen	2.74
Ankylosing spondylitis	Worsen	4.75
Asthma	Worsen	2.74
Atherosclerosis	Improves	-4.71
Autism	Worsen	0.19
Brain Trauma	Improves	-3.31
Carcinoma	Improves	-3.18
Celiac Disease	Improves	-3.1
Chronic Fatigue Syndrome	Improves	-3.58
Chronic Kidney Disease	Improves	-2.41
Chronic urticaria (Hives)	Improves	-3.06
Colorectal Cancer	Improves	-2.09
Crohn's Disease	Improves	-4.72
cystic fibrosis	Improves	-3.57
Depression	Improves	-3.49
Epilepsy	Improves	-2.54
Generalized anxiety disorder	Improves	-3.76
Graves' disease	Worsen	2.74
Hashimoto's thyroiditis	Improves	-2.42
High Blood Pressure	Worsen	1.09
Histamine Issues	Improves	-4.74
IgA nephropathy (IgAN)	Improves	-1.35
Inflammatory Bowel Disease	Improves	-4.85
Irritable Bowel Syndrome	Improves	-3.77
Liver Cirrhosis	Improves	-4.69
ME/CFS with IBS	Worsen	0
ME/CFS without IBS	Improves	-2.43
Mood Disorders	Improves	-2.74
Multiple Sclerosis	Improves	-2.92
neuropsychiatric disorders (PANDAS, PANS)	Improves	-2.42
Obesity	Improves	-3.37
Osteoporosis	Improves	-2.41
Parkinson's Disease	Improves	-2.74
Psoriasis	Improves	-3.44
Rheumatoid arthritis	Improves	-3.98
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	Improves	-4.02
Rosacea	Worsen	2.44
Schizophrenia	Worsen	2.74
Sjögren syndrome	Improves	-2.41
Small Intestinal Bacterial Overgrowth (SIBO)	Improves	-4.41
Stress / posttraumatic stress disorder	Improves	-4.78
Systemic Lupus Erythematosus	Improves	-2.63
Type 1 Diabetes	Worsen	2.48
Type 2 Diabetes	Improves	-3.9
Ulcerative colitis	Improves	-2.38

Bacteria Impacted

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.