We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Neuroendocrine: Feeling like you have a low temperature | Improves | -2.74 |
Neurological: emotional overload | Improves | -2.74 |
Neurological: fasciculations | Improves | -2.74 |
Neurological: High degree of Empathy before onset | Improves | -2.74 |
Neurological: Short-term memory issues | Improves | -2.74 |
Neurological: Spatial instability and disorientation | Improves | -2.74 |
Onset: less than 02 years since onset | Improves | -2.74 |
Post-exertional malaise: Worsening of symptoms after mild mental activity | Improves | -2.74 |
We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is according to the microbiome shifts reported in studies. Clinical studies may show different results
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Allergies | Improves | -2.74 |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | Worsen | 2.44 |
Ankylosing spondylitis | Improves | -3.91 |
Asthma | Worsen | 0 |
Atherosclerosis | Worsen | 2.92 |
Autism | Worsen | 0 |
Bipolar Disorder | Improves | -2.43 |
Brain Trauma | Worsen | 2.74 |
Celiac Disease | Worsen | 0 |
Chronic Fatigue Syndrome | Worsen | 3.08 |
Chronic Lyme | Worsen | 2.74 |
Colorectal Cancer | Improves | -2.43 |
COVID-19 | Worsen | 3.25 |
Crohn's Disease | Worsen | 3.4 |
cystic fibrosis | Worsen | 2.43 |
Depression | Worsen | 3.4 |
Eczema | Worsen | 3.8 |
Graves' disease | Improves | -2.74 |
Histamine Issues | Worsen | 2.66 |
IgA nephropathy (IgAN) | Worsen | 2.74 |
Inflammatory Bowel Disease | Worsen | 2.43 |
Irritable Bowel Syndrome | Worsen | 3.4 |
Liver Cirrhosis | Worsen | 3.14 |
ME/CFS without IBS | Worsen | 3.08 |
Mood Disorders | Worsen | 2.74 |
Multiple Sclerosis | Worsen | 3.08 |
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | Worsen | 4.01 |
Obesity | Worsen | 2.74 |
Parkinson's Disease | Worsen | 3.53 |
rheumatoid arthritis (RA),Spondyloarthritis (SpA) | Worsen | 3.26 |
Rosacea | Improves | -2.44 |
Schizophrenia | Improves | -2.74 |
Stress / posttraumatic stress disorder | Worsen | 3.4 |
Systemic Lupus Erythematosus | Worsen | 2.74 |
Type 2 Diabetes | Worsen | 2.74 |
Ulcerative colitis | Worsen | 1.65 |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.