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Heart Health: Grapes are rich in polyphenols, particularly resveratrol, quercetin, and catechins, which have been associated with heart health benefits. These compounds may help lower blood pressure, reduce inflammation, improve blood flow, and protect against oxidative stress, thereby reducing the risk of cardiovascular diseases such as heart disease and stroke.
Antioxidant Activity: Grapes contain antioxidants such as flavonoids, anthocyanins, and vitamin C, which help neutralize harmful free radicals in the body. Antioxidants protect cells from damage caused by oxidative stress and may help prevent chronic diseases such as cancer, diabetes, and neurodegenerative disorders.
Anti-Inflammatory Effects: Compounds found in grapes, including resveratrol and flavonoids, exhibit anti-inflammatory properties. Consuming grapes or grape products may help reduce inflammation in the body, which is implicated in various chronic conditions such as arthritis, inflammatory bowel disease (IBD), and cardiovascular disease.
Gut Health: Grapes contain dietary fiber and polyphenols that can promote gut health by supporting the growth of beneficial gut bacteria and improving digestion. Fiber helps regulate bowel movements, prevent constipation, and maintain a healthy balance of gut microbiota, which is important for overall digestive health and immune function.
Cancer Prevention: Some studies suggest that the polyphenols and other bioactive compounds in grapes may have anticancer properties. Resveratrol, in particular, has been investigated for its potential role in inhibiting cancer cell growth and reducing the risk of certain cancers, including breast, colon, and prostate cancer. However, more research is needed to fully understand the effects of grapes on cancer prevention and treatment.
Brain Health: Resveratrol and other polyphenols in grapes have been studied for their potential neuroprotective effects. These compounds may help protect brain cells from damage, reduce inflammation in the brain, improve cognitive function, and lower the risk of neurodegenerative diseases such as Alzheimer's and Parkinson's disease.
Weight Management: Grapes are relatively low in calories and fat but rich in water and dietary fiber, making them a satisfying and nutritious snack option for weight management. Including grapes in a balanced diet may help promote feelings of fullness, reduce calorie intake, and support weight loss or weight maintenance goals.
Skin Health: The antioxidants and polyphenols in grapes may benefit skin health by protecting against UV damage, reducing inflammation, and promoting collagen production. Grape seed extract, derived from grape seeds, is often used in skincare products for its potential anti-aging and moisturizing effects.
| Rank | Probiotic | Impact |
|---|---|---|
| species | Akkermansia muciniphila | Increases |
| species | Bifidobacterium adolescentis | Increases |
| species | Bifidobacterium bifidum | Increases |
| species | Bifidobacterium breve | Increases |
| species | Bifidobacterium catenulatum | Increases |
| species | Bifidobacterium longum | Increases |
| species | Bifidobacterium pseudocatenulatum | Increases |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Abdominal Aortic Aneurysm | 0.4 | 0.2 | 1 |
| Acne | 2.5 | 0.5 | 4 |
| ADHD | 1.3 | 1.5 | -0.15 |
| Allergic Rhinitis (Hay Fever) | 1.2 | 1.2 | |
| Allergies | 1.6 | 2 | -0.25 |
| Allergy to milk products | 0.9 | 0.9 | |
| Alopecia (Hair Loss) | 0.9 | -0.9 | |
| Alzheimer's disease | 3.2 | 3.3 | -0.03 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 0.8 | 1.6 | -1 |
| Ankylosing spondylitis | 0.2 | 0.6 | -2 |
| Anorexia Nervosa | 0.8 | 0.2 | 3 |
| Antiphospholipid syndrome (APS) | 0.4 | -0.4 | |
| Asthma | 1.6 | 0.6 | 1.67 |
| Atherosclerosis | 0.5 | 0.6 | -0.2 |
| Atrial fibrillation | 1.2 | 1.2 | 0 |
| Autism | 3.6 | 3 | 0.2 |
| Barrett esophagus cancer | 0.8 | 0.8 | |
| Bipolar Disorder | 0.9 | 0.3 | 2 |
| Brain Trauma | 0.4 | 1.1 | -1.75 |
| Carcinoma | 1.2 | 1.1 | 0.09 |
| Celiac Disease | 2.9 | 1 | 1.9 |
| Cerebral Palsy | 1.1 | -1.1 | |
| Chronic Fatigue Syndrome | 1.1 | 1.5 | -0.36 |
| Chronic Kidney Disease | 0.3 | 0.6 | -1 |
| Chronic Urticaria (Hives) | 0.5 | 0.5 | |
| Coagulation / Micro clot triggering bacteria | 0.6 | -0.6 | |
| Colorectal Cancer | 1.2 | 2.2 | -0.83 |
| Coronary artery disease | 0.8 | -0.8 | |
| COVID-19 | 3 | 2.8 | 0.07 |
| Crohn's Disease | 4 | 2.2 | 0.82 |
| cystic fibrosis | 0.6 | 0.6 | |
| Depression | 3.5 | 4.3 | -0.23 |
| Dermatomyositis | 0.9 | 0.9 | |
| Eczema | 0.9 | 0.9 | |
| Endometriosis | 0.4 | 0.9 | -1.25 |
| Eosinophilic Esophagitis | 1.1 | 1.1 | |
| Epilepsy | 1.9 | 1.8 | 0.06 |
| Fibromyalgia | 0.6 | 0.2 | 2 |
| Functional constipation / chronic idiopathic constipation | 0.9 | 1.7 | -0.89 |
| gallstone disease (gsd) | 0.6 | 0.6 | |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 0.3 | -0.3 | |
| Generalized anxiety disorder | 0.8 | 0.8 | |
| giant cell arteritis | 0.2 | -0.2 | |
| Gout | 0.8 | -0.8 | |
| Graves' disease | 1.1 | 1.2 | -0.09 |
| Halitosis | 0.4 | -0.4 | |
| Hashimoto's thyroiditis | 0.6 | 1.5 | -1.5 |
| Hidradenitis Suppurativa | 0.7 | 0.2 | 2.5 |
| Histamine Issues,Mast Cell Issue, DAO Insufficiency | 0.3 | 0.6 | -1 |
| hypercholesterolemia (High Cholesterol) | 1.1 | 0.8 | 0.38 |
| hyperglycemia | 2.2 | 0.5 | 3.4 |
| Hyperlipidemia (High Blood Fats) | 1.7 | -1.7 | |
| hypersomnia | 0.4 | -0.4 | |
| hypertension (High Blood Pressure | 2.1 | 3.3 | -0.57 |
| Hypothyroidism | 0.6 | 0.6 | |
| Hypoxia | 0.5 | -0.5 | |
| IgA nephropathy (IgAN) | 0.8 | 0.8 | |
| Inflammatory Bowel Disease | 2.3 | 1.3 | 0.77 |
| Insomnia | 0.3 | 0.3 | |
| Intelligence | 0.2 | 0.2 | |
| Intracranial aneurysms | 0.2 | -0.2 | |
| Irritable Bowel Syndrome | 2.3 | 2.7 | -0.17 |
| Juvenile idiopathic arthritis | 0.3 | 0.3 | |
| Liver Cirrhosis | 2.3 | 1.9 | 0.21 |
| Long COVID | 2.9 | 5.4 | -0.86 |
| Lung Cancer | 1.3 | 1.3 | |
| ME/CFS with IBS | 0.6 | 0.6 | |
| ME/CFS without IBS | 0.6 | 0.2 | 2 |
| Menopause | 0.2 | 0.4 | -1 |
| Metabolic Syndrome | 6.3 | 5.5 | 0.15 |
| Mood Disorders | 4.4 | 5.6 | -0.27 |
| multiple chemical sensitivity [MCS] | 0.6 | 0.5 | 0.2 |
| Multiple Sclerosis | 1.8 | 3 | -0.67 |
| Multiple system atrophy (MSA) | 0.8 | 1 | -0.25 |
| Neuropathy (all types) | 1 | -1 | |
| neuropsychiatric disorders (PANDAS, PANS) | 1.1 | 1.1 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 1.9 | 1.2 | 0.58 |
| NonCeliac Gluten Sensitivity | 0.6 | 0.6 | |
| Obesity | 4.4 | 2.9 | 0.52 |
| obsessive-compulsive disorder | 1.5 | 0.2 | 6.5 |
| Osteoarthritis | 0.5 | 0.5 | |
| Osteoporosis | 1.4 | 1.4 | |
| Parkinson's Disease | 2 | 3.9 | -0.95 |
| Polycystic ovary syndrome | 1.1 | 1.7 | -0.55 |
| Postural orthostatic tachycardia syndrome | 0.6 | 0.6 | |
| Premenstrual dysphoric disorder | 0.6 | -0.6 | |
| Psoriasis | 0.7 | 1.4 | -1 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 2.5 | 3.5 | -0.4 |
| Rosacea | 0.3 | 0.6 | -1 |
| Schizophrenia | 1.7 | 2.9 | -0.71 |
| scoliosis | 0.6 | -0.6 | |
| Sjögren syndrome | 0.8 | 0.3 | 1.67 |
| Sleep Apnea | 0.9 | -0.9 | |
| Small Intestinal Bacterial Overgrowth (SIBO) | 0.7 | 0.7 | |
| Stress / posttraumatic stress disorder | 1.4 | 2.4 | -0.71 |
| Systemic Lupus Erythematosus | 2.1 | 0.2 | 9.5 |
| Tic Disorder | 0.8 | 0.2 | 3 |
| Tourette syndrome | 0.5 | -0.5 | |
| Type 1 Diabetes | 1 | 0.3 | 2.33 |
| Type 2 Diabetes | 3.9 | 2.8 | 0.39 |
| Ulcerative colitis | 3.2 | 2.2 | 0.45 |
| Unhealthy Ageing | 1.7 | 0.2 | 7.5 |
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