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Digestive Symptoms: For individuals with IBS or other gastrointestinal disorders, high FODMAP foods can trigger symptoms such as abdominal pain, bloating, gas, diarrhea, and constipation. FODMAPs are poorly absorbed in the small intestine and can ferment in the large intestine, leading to the production of gas and changes in bowel habits.
Irritable Bowel Syndrome (IBS) Management: The low-FODMAP diet is often used as a dietary intervention to manage symptoms of IBS, particularly in individuals with irritable bowel syndrome with diarrhea (IBS-D) or irritable bowel syndrome with mixed bowel habits (IBS-M). By reducing intake of high-FODMAP foods, individuals may experience symptom relief and improvements in overall bowel function.
Symptom Flare-ups: Consuming high-FODMAP foods can lead to symptom flare-ups in susceptible individuals, even if they do not have a diagnosed gastrointestinal disorder. These symptoms may include bloating, abdominal discomfort, and changes in bowel movements. Identifying and avoiding trigger foods is important for managing symptoms and preventing flare-ups.
Nutritional Adequacy: Following a strict low-FODMAP diet may result in reduced intake of certain nutrients, including fiber, prebiotics, and some vitamins and minerals found in high-FODMAP foods such as fruits, vegetables, legumes, and whole grains. It's essential for individuals on a low-FODMAP diet to work with a healthcare professional or registered dietitian to ensure nutritional adequacy and prevent deficiencies.
Microbiome Changes: FODMAPs can influence the composition and activity of the gut microbiota. A high-FODMAP diet may promote the growth of certain bacteria in the gut, leading to alterations in the microbiome. Changes in gut microbiota composition may affect gastrointestinal function, immune function, and overall health.
Impact on Mental Health: Gastrointestinal symptoms associated with a high-FODMAP diet can impact mental health and quality of life. Chronic digestive symptoms can lead to stress, anxiety, and depression in affected individuals. Conversely, improvements in gastrointestinal symptoms through dietary management may lead to better mental well-being.
Individual Variability: It's important to note that not everyone will experience adverse effects from high-FODMAP foods. Some individuals may tolerate certain FODMAPs better than others, and tolerance levels can vary depending on factors such as gut microbiota composition, gastrointestinal motility, and underlying gastrointestinal conditions.
| Rank | Probiotic | Impact |
|---|
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Allergies | 0.5 | 0.5 | |
| Anorexia Nervosa | 0.5 | 0.5 | |
| Carcinoma | 0.5 | 0.5 | 0 |
| Celiac Disease | 0.5 | -0.5 | |
| Crohn's Disease | 0.7 | 0.5 | 0.4 |
| Functional constipation / chronic idiopathic constipation | 0.5 | 0.5 | |
| Hidradenitis Suppurativa | 0.1 | 0.1 | |
| hypercholesterolemia (High Cholesterol) | 0.2 | 0.2 | |
| Inflammatory Bowel Disease | 0.5 | -0.5 | |
| Irritable Bowel Syndrome | 0.5 | 0.5 | 0 |
| Liver Cirrhosis | 0.5 | 0.5 | |
| Metabolic Syndrome | 0.7 | 0.7 | 0 |
| Mood Disorders | 0.5 | 0.5 | |
| Multiple Sclerosis | 1.5 | 1.5 | |
| Obesity | 0.7 | 1 | -0.43 |
| obsessive-compulsive disorder | 0.5 | -0.5 | |
| Parkinson's Disease | 0.5 | 0.5 | |
| Psoriasis | 0.5 | 0.5 | |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 0.5 | 0.5 | |
| Schizophrenia | 0.5 | 0.5 | |
| Small Intestinal Bacterial Overgrowth (SIBO) | 1 | 1 | |
| Stress / posttraumatic stress disorder | 0.5 | 0.5 | |
| Type 2 Diabetes | 0.7 | 0.7 | 0 |
| Ulcerative colitis | 0.5 | 0.5 | 0 |
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