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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomImpactPredictor of Bacteria Shift
Age: 20-30Improves-1.19
Age: 60-70Improves-1.7
Asymptomatic: No Health IssuesWorsen2.72
Blood Type: A PositiveWorsen1.86
Blood Type: O PositiveWorsen1.86
Comorbid-Mouth: Dry MouthImproves-2.8
Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndromeImproves-1.62
Comorbid: Histamine or Mast Cell issuesImproves-1.7
Comorbid: MigraineWorsen1.86
Comorbid: Multiple Chemical SensitivityImproves-2.9
DePaul University Fatigue Questionnaire : AllergiesImproves-2.72
DePaul University Fatigue Questionnaire : Anxiety/tensionImproves-2.72
DePaul University Fatigue Questionnaire : FatigueImproves-2.28
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired Improves-2.28
DePaul University Fatigue Questionnaire : Walking up early in the morning (e.g. 3AM)Improves-2.94
General: FatigueImproves-2.9
General: HeadachesImproves-1.62
Immune Manifestations: Alcohol IntolerantImproves-1.62
Joint: Stiffness and swellingImproves-1.7
Neuroendocrine Manifestations: Excessive adrenalineImproves-1.68
Neuroendocrine Manifestations: intolerance of extremes of heat and coldImproves-2.9
Neuroendocrine Manifestations: Muscle weakness Improves-3.51
Neuroendocrine: Alcohol intoleranceImproves-1.7
Neuroendocrine: Lost or gained weight without tryingImproves-3.51
Neurological: Slowed speechImproves-1.61
Official Diagnosis: Mast Cell DysfunctionImproves-1.7
Onset: GradualImproves-2.65
Pain: Joint painImproves-1.56
Sleep: Problems staying asleepImproves-1.7
Sleep: Waking up early in the morning (e.g. 3 AM)Improves-1.7

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomImpactPredictor of Bacteria Shift
AcneWorsen0
ADHDImproves-2.72
AllergiesImproves-1.94
Alzheimer's diseaseWorsen4.03
Amyotrophic lateral sclerosis (ALS) Motor NeuronWorsen3.72
Ankylosing spondylitisWorsen3.73
AsthmaImproves-2.9
AtherosclerosisWorsen3.96
AutismWorsen1.52
Barrett esophagus cancerImproves-3.16
Bipolar DisorderWorsen1.9
Brain TraumaImproves-1.45
Celiac DiseaseImproves-4.34
Cerebral PalsyWorsen2.9
Chronic Fatigue SyndromeImproves-3.38
Chronic Kidney DiseaseImproves-2.28
Colorectal CancerImproves-1.93
Coronary artery disease Improves-1.44
COVID-19Worsen1.04
Crohn's DiseaseWorsen2.62
DepressionWorsen2.64
EpilepsyImproves-3.48
FibromyalgiaImproves-2.72
Functional constipation / chronic idiopathic constipationWorsen2.72
gallstone disease (gsd)Worsen2.72
Gastroesophageal reflux disease (Gerd) including Barrett's esophagusImproves-1.46
High Blood PressureImproves-2.72
Histamine IssuesWorsen1.84
Histamine Issues From UbiomeImproves-2.96
Hyperlipidemia (High Blood Fats)Worsen2.96
IgA nephropathy (IgAN)Improves-3.38
Inflammatory Bowel DiseaseWorsen1.98
Irritable Bowel SyndromeImproves-3.52
Liver CirrhosisWorsen3.42
ME/CFS with IBSWorsen0
ME/CFS without IBSWorsen1.7
Metabolic SyndromeImproves-2.9
Multiple SclerosisWorsen4.16
Multiple system atrophy (MSA)Worsen3.48
Nonalcoholic Fatty Liver Disease (nafld) NonalcoholicImproves-2.58
ObesityImproves-4.31
OsteoporosisWorsen3.71
Parkinson's DiseaseWorsen5.5
PsoriasisWorsen3.72
rheumatoid arthritis (RA),Spondyloarthritis (SpA)Improves-3.06
RosaceaImproves-2.72
SchizophreniaWorsen4.12
Small Intestinal Bacterial Overgrowth (SIBO)Improves-2.48
Stress / posttraumatic stress disorderImproves-3.31
Systemic Lupus ErythematosusImproves-2.58
Type 1 DiabetesImproves-3.08
Type 2 DiabetesImproves-3.51
Ulcerative colitisImproves-2.88

Bacteria Impacted

Suggest a missed study:

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Staphylococcaceae family Decreases 📓 Source Study
Actinomycetaceae family Increases 📓 Source Study
Ruminococcaceae family Increases 📓 Source Study
Verrucomicrobiaceae family Increases 📓 Source Study
Clostridium genus Decreases 📓 Source Study
Escherichia genus Decreases 📓 Source Study
Kluyvera genus Decreases 📓 Source Study
Staphylococcus genus Decreases 📓 Source Study
Auricoccus genus Decreases 👪 Source Study
Jeotgalicoccus genus Decreases 👪 Source Study
Macrococcus genus Decreases 👪 Source Study
Nosocomiicoccus genus Decreases 👪 Source Study
Salinicoccus genus Decreases 👪 Source Study
Acetanaerobacterium genus Increases 👪 Source Study
Actinobaculum genus Increases 👪 Source Study
Actinotignum genus Increases 👪 Source Study
Agathobaculum genus Increases 👪 Source Study
Anaerofilum genus Increases 👪 Source Study
Anaeromassilibacillus genus Increases 👪 Source Study
Angelakisella genus Increases 👪 Source Study
Arcanobacterium genus Increases 👪 Source Study
Bittarella genus Increases 👪 Source Study
Brevifollis genus Increases 👪 Source Study
Candidatus Soleaferrea genus Increases 👪 Source Study
Caproiciproducens genus Increases 👪 Source Study
Ethanoligenens genus Increases 👪 Source Study
Flaviflexus genus Increases 👪 Source Study
Flavonifractor genus Increases 👪 Source Study
Fournierella genus Increases 👪 Source Study
Gemmiger genus Increases 👪 Source Study
Gorbachella genus Increases 👪 Source Study
Haloferula genus Increases 👪 Source Study
Hydrogenoanaerobacterium genus Increases 👪 Source Study
Luteolibacter genus Increases 👪 Source Study
Mobiluncus genus Increases 👪 Source Study
Negativibacillus genus Increases 👪 Source Study
Neglecta genus Increases 👪 Source Study
Papillibacter genus Increases 👪 Source Study
Persicirhabdus genus Increases 👪 Source Study
Phocea genus Increases 👪 Source Study
Prosthecobacter genus Increases 👪 Source Study
Pseudoflavonifractor genus Increases 👪 Source Study
Roseimicrobium genus Increases 👪 Source Study
Ruthenibacterium genus Increases 👪 Source Study
Schaalia genus Increases 👪 Source Study
Sporobacter genus Increases 👪 Source Study
Trueperella genus Increases 👪 Source Study
Varibaculum genus Increases 👪 Source Study
Verrucomicrobium genus Increases 👪 Source Study
Actinomyces genus Increases 📓 Source Study
Akkermansia genus Increases 📓 Source Study
Akkermansia genus Increases 📓 Source Study
Akkermansia genus Increases 📓 Source Study
Bacteroides genus Increases 📓 Source Study
Lactobacillus genus Increases 📓 Source Study
Lactobacillus genus Increases 📓 Source Study
Oscillospira genus Increases 📓 Source Study
Firmicutes phylum Decreases 📓 Source Study
Bacteroidota phylum Increases 📓 Source Study
[Clostridium] leptum species Decreases 📓 Source Study
Escherichia coli species Decreases 📓 Source Study
[Clostridium] spiroforme species Decreases 👪 Source Study
ATCC 35538 species Decreases 👪 Source Study
ATCC 35539 species Decreases 👪 Source Study
ATCC 43808 species Decreases 👪 Source Study
ATCC 43809 species Decreases 👪 Source Study
ATCC 49168 species Decreases 👪 Source Study
ATCC 49171 species Decreases 👪 Source Study
ATCC 49910 species Decreases 👪 Source Study
ATCC 51365 species Decreases 👪 Source Study
ATCC 700337 species Decreases 👪 Source Study
ATCC 700373 species Decreases 👪 Source Study
CCM 7045 species Decreases 👪 Source Study
CCM 7213 species Decreases 👪 Source Study
CCUG 51270 species Decreases 👪 Source Study
CCUG 59809 species Decreases 👪 Source Study
DSM 28299 species Decreases 👪 Source Study
DSM 28300 species Decreases 👪 Source Study
LTH 3734 species Decreases 👪 Source Study
Staphylococcus auricularis species Decreases 👪 Source Study
Staphylococcus capitis species Decreases 👪 Source Study
Staphylococcus chromogenes species Decreases 👪 Source Study
Staphylococcus cohnii species Decreases 👪 Source Study
Staphylococcus devriesei species Decreases 👪 Source Study
Staphylococcus equorum species Decreases 👪 Source Study
Staphylococcus haemolyticus species Decreases 👪 Source Study
Staphylococcus pasteuri species Decreases 👪 Source Study
Staphylococcus piscifermentans species Decreases 👪 Source Study
Staphylococcus saprophyticus species Decreases 👪 Source Study
Staphylococcus sciuri species Decreases 👪 Source Study
Staphylococcus simulans species Decreases 👪 Source Study
Staphylococcus sp. 3035O2 species Decreases 👪 Source Study
Staphylococcus sp. 3356O2 species Decreases 👪 Source Study
Staphylococcus sp. FXY54 species Decreases 👪 Source Study
Staphylococcus sp. L10 species Decreases 👪 Source Study
Staphylococcus sp. M0911 species Decreases 👪 Source Study
Staphylococcus sp. SDB 2975 species Decreases 👪 Source Study
Staphylococcus sp. WB17-17 species Decreases 👪 Source Study
Staphylococcus sp. WB18-16 species Decreases 👪 Source Study
Staphylococcus stepanovicii species Decreases 👪 Source Study
Staphylococcus vitulinus species Decreases 👪 Source Study
Staphylococcus warneri species Decreases 👪 Source Study
Staphylococcus xylosus species Decreases 👪 Source Study
Actinobacterium israeli species Increases 👪 Source Study
Actinomyces dentalis species Increases 👪 Source Study
Actinomyces denticolens species Increases 👪 Source Study
Actinomyces europaeus species Increases 👪 Source Study
Actinomyces gaoshouyii species Increases 👪 Source Study
Actinomyces genomosp. C1 species Increases 👪 Source Study
Actinomyces graevenitzii species Increases 👪 Source Study
Actinomyces hongkongensis species Increases 👪 Source Study
Actinomyces hordeovulneris species Increases 👪 Source Study
Actinomyces johnsonii species Increases 👪 Source Study
Actinomyces massiliensis species Increases 👪 Source Study
Actinomyces naeslundii species Increases 👪 Source Study
Actinomyces nasicola species Increases 👪 Source Study
Actinomyces neuii species Increases 👪 Source Study
Actinomyces oris species Increases 👪 Source Study
Actinomyces pacaensis species Increases 👪 Source Study
Actinomyces radicidentis species Increases 👪 Source Study
Actinomyces ruminicola species Increases 👪 Source Study
Actinomyces slackii species Increases 👪 Source Study
Actinomyces sp. species Increases 👪 Source Study
Actinomyces sp. 2002-2301122 species Increases 👪 Source Study
Actinomyces sp. 2129 species Increases 👪 Source Study
Actinomyces sp. 299 species Increases 👪 Source Study
Actinomyces sp. 410 species Increases 👪 Source Study
Actinomyces sp. canine oral taxon 374 species Increases 👪 Source Study
Actinomyces sp. canine oral taxon 417 species Increases 👪 Source Study
Actinomyces sp. CCUG 28744 species Increases 👪 Source Study
Actinomyces sp. dk561 species Increases 👪 Source Study
Actinomyces sp. ICM34 species Increases 👪 Source Study
Actinomyces sp. ICM39 species Increases 👪 Source Study
Actinomyces sp. ICM41 species Increases 👪 Source Study
Actinomyces sp. ICM47 species Increases 👪 Source Study
Actinomyces sp. ICM54 species Increases 👪 Source Study
Actinomyces sp. ICM58 species Increases 👪 Source Study
Actinomyces sp. oral strain B19SC species Increases 👪 Source Study
Actinomyces sp. oral strain Hal-1065 species Increases 👪 Source Study
Actinomyces sp. oral strain Hal-1083 species Increases 👪 Source Study
Actinomyces sp. oral taxon 175 species Increases 👪 Source Study
Actinomyces sp. oral taxon 180 species Increases 👪 Source Study
Actinomyces sp. oral taxon 414 species Increases 👪 Source Study
Actinomyces sp. oral taxon 448 species Increases 👪 Source Study
Actinomyces sp. oral taxon 848 species Increases 👪 Source Study
Actinomyces sp. oral taxon 897 species Increases 👪 Source Study
Actinomyces sp. ph3 species Increases 👪 Source Study
Actinomyces sp. S4-C9 species Increases 👪 Source Study
Actinomyces sp. S5-BM9 species Increases 👪 Source Study
Actinomyces sp. S6-Spd3 species Increases 👪 Source Study
Actinomyces sp. S8 AA1-3 species Increases 👪 Source Study
Actinomyces sp. S9 HS-9 species Increases 👪 Source Study
Actinomyces sp. S9 PR-21 species Increases 👪 Source Study
Actinomyces sp. Z16 species Increases 👪 Source Study
Actinomyces sp. ZSY-1 species Increases 👪 Source Study
Actinomyces timonensis species Increases 👪 Source Study
Actinomyces viscosus species Increases 👪 Source Study
Akkermansia glycaniphila species Increases 👪 Source Study
Akkermansia sp. species Increases 👪 Source Study
ATCC 700934 species Increases 👪 Source Study
BCRC 17755 species Increases 👪 Source Study
CCUG 48460 species Increases 👪 Source Study
CCUG 63301 species Increases 👪 Source Study
CCUG 63631 species Increases 👪 Source Study
CRBIP 24.179 species Increases 👪 Source Study
DSM 19284 species Increases 👪 Source Study
JCM 1039 species Increases 👪 Source Study
JCM 32269 species Increases 👪 Source Study
Lactobacillus acetotolerans species Increases 👪 Source Study
Lactobacillus acidipiscis species Increases 👪 Source Study
Lactobacillus agilis species Increases 👪 Source Study
Lactobacillus alimentarius species Increases 👪 Source Study
Lactobacillus allii species Increases 👪 Source Study
Lactobacillus amylolyticus species Increases 👪 Source Study
Lactobacillus animalis species Increases 👪 Source Study
Lactobacillus antri species Increases 👪 Source Study
Lactobacillus apis species Increases 👪 Source Study
Lactobacillus backii species Increases 👪 Source Study
Lactobacillus bifermentans species Increases 👪 Source Study
Lactobacillus bombi species Increases 👪 Source Study
Lactobacillus brantae species Increases 👪 Source Study
Lactobacillus buchneri species Increases 👪 Source Study
Lactobacillus ceti species Increases 👪 Source Study
Lactobacillus coleohominis species Increases 👪 Source Study
Lactobacillus composti species Increases 👪 Source Study
Lactobacillus coryniformis species Increases 👪 Source Study
Lactobacillus crustorum species Increases 👪 Source Study
Lactobacillus curieae species Increases 👪 Source Study
Lactobacillus equi species Increases 👪 Source Study
Lactobacillus equigenerosi species Increases 👪 Source Study
Lactobacillus farciminis species Increases 👪 Source Study
Lactobacillus fermentum species Increases 👪 Source Study
Lactobacillus floricola species Increases 👪 Source Study
Lactobacillus frumenti species Increases 👪 Source Study
Lactobacillus fuchuensis species Increases 👪 Source Study
Lactobacillus gallinarum species Increases 👪 Source Study
Lactobacillus ginsenosidimutans species Increases 👪 Source Study
Lactobacillus hamsteri species Increases 👪 Source Study
Lactobacillus harbinensis species Increases 👪 Source Study
Lactobacillus hayakitensis species Increases 👪 Source Study
Lactobacillus heilongjiangensis species Increases 👪 Source Study
Lactobacillus helveticus species Increases 👪 Source Study
Lactobacillus hilgardii species Increases 👪 Source Study
Lactobacillus hokkaidonensis species Increases 👪 Source Study
Lactobacillus ingluviei species Increases 👪 Source Study
Lactobacillus intestinalis species Increases 👪 Source Study
Lactobacillus jensenii species Increases 👪 Source Study
Lactobacillus johnsonii species Increases 👪 Source Study
Lactobacillus kalixensis species Increases 👪 Source Study
Lactobacillus kefiranofaciens species Increases 👪 Source Study
Lactobacillus kefiri species Increases 👪 Source Study
Lactobacillus kunkeei species Increases 👪 Source Study
Lactobacillus lindneri species Increases 👪 Source Study
Lactobacillus malefermentans species Increases 👪 Source Study
Lactobacillus mali species Increases 👪 Source Study
Lactobacillus mellifer species Increases 👪 Source Study
Lactobacillus mellis species Increases 👪 Source Study
Lactobacillus murinus species Increases 👪 Source Study
Lactobacillus namurensis species Increases 👪 Source Study
Lactobacillus nodensis species Increases 👪 Source Study
Lactobacillus oligofermentans species Increases 👪 Source Study
Lactobacillus oris species Increases 👪 Source Study
Lactobacillus oryzae species Increases 👪 Source Study
Lactobacillus ozensis species Increases 👪 Source Study
Lactobacillus pantheris species Increases 👪 Source Study
Lactobacillus parabuchneri species Increases 👪 Source Study
Lactobacillus paracollinoides species Increases 👪 Source Study
Lactobacillus parafarraginis species Increases 👪 Source Study
Lactobacillus paralimentarius species Increases 👪 Source Study
Lactobacillus paraplantarum species Increases 👪 Source Study
Lactobacillus pentosus species Increases 👪 Source Study
Lactobacillus perolens species Increases 👪 Source Study
Lactobacillus plajomi species Increases 👪 Source Study
Lactobacillus pontis species Increases 👪 Source Study
Lactobacillus psittaci species Increases 👪 Source Study
Lactobacillus rapi species Increases 👪 Source Study
Lactobacillus rodentium species Increases 👪 Source Study
Lactobacillus sakei species Increases 👪 Source Study
Lactobacillus saniviri species Increases 👪 Source Study
Lactobacillus satsumensis species Increases 👪 Source Study
Lactobacillus selangorensis species Increases 👪 Source Study
Lactobacillus songhuajiangensis species Increases 👪 Source Study
Lactobacillus sp. species Increases 👪 Source Study
Lactobacillus sp. 7_1_47FAA species Increases 👪 Source Study
Lactobacillus sp. Akhmro1 species Increases 👪 Source Study
Lactobacillus sp. BHWM-4 species Increases 👪 Source Study
Lactobacillus sp. C30An8 species Increases 👪 Source Study
Lactobacillus sp. C4I1 species Increases 👪 Source Study
Lactobacillus sp. C4I18 species Increases 👪 Source Study
Lactobacillus sp. CBA3606 species Increases 👪 Source Study
Lactobacillus sp. H7_2_4MCO2 species Increases 👪 Source Study
Lactobacillus sp. H7_6_6MCO2 species Increases 👪 Source Study
Lactobacillus sp. HBUAS52074 species Increases 👪 Source Study
Lactobacillus sp. HSLZ-75 species Increases 👪 Source Study
Lactobacillus sp. MYMRS/TEN2 species Increases 👪 Source Study
Lactobacillus sp. NRCT-KU 1 species Increases 👪 Source Study
Lactobacillus sp. S16 species Increases 👪 Source Study
Lactobacillus sp. T059 species Increases 👪 Source Study
Lactobacillus sp. TAB-22 species Increases 👪 Source Study
Lactobacillus sp. TAB-29 species Increases 👪 Source Study
Lactobacillus tucceti species Increases 👪 Source Study
Lactobacillus vaccinostercus species Increases 👪 Source Study
Lactobacillus vaginalis species Increases 👪 Source Study
Lactobacillus vini species Increases 👪 Source Study
Lactobacillus zymae species Increases 👪 Source Study
LMG:9496 species Increases 👪 Source Study
Oscillospira guilliermondii species Increases 👪 Source Study
Rothia mucilaginosa species Increases 👪 Source Study
Streptococcus oralis species Increases 👪 Source Study

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