We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Blood Type: A Positive | Worsen | 1.86 |
Blood Type: O Positive | Worsen | 1.86 |
Comorbid-Mouth: Dry Mouth | Improves | -2.74 |
Comorbid: Histamine or Mast Cell issues | Improves | -1.7 |
Comorbid: Inflammatory bowel disease | Worsen | 1.86 |
Comorbid: Migraine | Worsen | 1.86 |
DePaul University Fatigue Questionnaire : Fatigue | Worsen | 1.86 |
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired | Worsen | 1.86 |
General: Headaches | Improves | -1.62 |
Joint: Stiffness and swelling | Improves | -1.7 |
Neuroendocrine Manifestations: Excessive adrenaline | Improves | -1.68 |
Neuroendocrine: Alcohol intolerance | Improves | -1.7 |
Neuroendocrine: Feeling like you have a low temperature | Improves | -2.74 |
Neurological: emotional overload | Improves | -2.74 |
Neurological: fasciculations | Improves | -2.74 |
Neurological: High degree of Empathy before onset | Improves | -2.74 |
Neurological: Short-term memory issues | Improves | -2.74 |
Neurological: Slowed speech | Improves | -1.61 |
Neurological: Spatial instability and disorientation | Improves | -2.74 |
Official Diagnosis: Mast Cell Dysfunction | Improves | -1.7 |
Post-exertional malaise: General | Improves | -2.74 |
Post-exertional malaise: Mentally tired after the slightest effort | Improves | -2.74 |
Post-exertional malaise: Physically drained or sick after mild activity | Improves | -2.74 |
Post-exertional malaise: Post-exertional malaise | Improves | -2.74 |
Post-exertional malaise: Rapid cognitive fatigability, | Improves | -2.74 |
Post-exertional malaise: Worsening of symptoms after mild mental activity | Improves | -2.74 |
Sleep: Problems staying asleep | Improves | -1.7 |
We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is according to the microbiome shifts reported in studies. Clinical studies may show different results
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Allergies | Improves | -2.74 |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | Improves | -2.74 |
Ankylosing spondylitis | Improves | -4.03 |
Asthma | Improves | -2.74 |
Atherosclerosis | Worsen | 4.58 |
Autism | Improves | -1.71 |
Brain Trauma | Worsen | 3.31 |
Carcinoma | Worsen | 3.18 |
Celiac Disease | Worsen | 0 |
Chronic Fatigue Syndrome | Worsen | 3.24 |
Chronic Kidney Disease | Worsen | 3.74 |
Chronic urticaria (Hives) | Improves | -1.4 |
Colorectal Cancer | Worsen | 3.59 |
Coronary artery disease | Improves | -1.44 |
Crohn's Disease | Worsen | 3.92 |
Depression | Worsen | 3.86 |
Epilepsy | Worsen | 3.31 |
Generalized anxiety disorder | Worsen | 3.69 |
Graves' disease | Improves | -2.74 |
Histamine Issues | Worsen | 3.58 |
Histamine Issues From Ubiome | Improves | -1.61 |
IgA nephropathy (IgAN) | Worsen | 2.4 |
Inflammatory Bowel Disease | Worsen | 3.88 |
Irritable Bowel Syndrome | Worsen | 2.56 |
Liver Cirrhosis | Worsen | 2.92 |
ME/CFS without IBS | Worsen | 1.7 |
Mood Disorders | Worsen | 2.74 |
Obesity | Worsen | 4.04 |
Osteoporosis | Worsen | 3.02 |
Parkinson's Disease | Improves | -2.55 |
Rheumatoid arthritis | Worsen | 3.81 |
rheumatoid arthritis (RA),Spondyloarthritis (SpA) | Worsen | 2.25 |
Rosacea | Improves | -2.44 |
Schizophrenia | Improves | -2.74 |
Sclerosis | Worsen | 1.96 |
Sjögren syndrome | Worsen | 3.02 |
Small Intestinal Bacterial Overgrowth (SIBO) | Worsen | 3.22 |
Stress / posttraumatic stress disorder | Worsen | 3.68 |
Systemic Lupus Erythematosus | Worsen | 2.96 |
Type 2 Diabetes | Worsen | 4.49 |
Ulcerative colitis | Improves | -3.15 |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.