lactobacillus reuteri (probiotics) ** full range

Check for interactions on Supp.AI

Sources

Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

Symptom	Impact	Predictor of Bacteria Shift
Age: 0-10	Improves	-3.56
Age: 20-30	Improves	-0.52
Age: 60-70	Improves	-1.7
Autism: Official Diagnosis	Worsen	1.76
Autonomic Manifestations: cardiac arrhythmias	Worsen	2.46
Autonomic Manifestations: Cortisol disorders or irregularity	Worsen	2.81
Autonomic Manifestations: Orthostatic intolerance	Worsen	1.79
Autonomic: Heart rate increase after standing	Improves	-1.55
Autonomic: Inability to tolerate an upright position	Improves	-3.17
Autonomic: Ocassional Tachycardia (Rapid heart beat)	Improves	-1.36
Autonomic: Shortness of breath	Worsen	2.84
Blood Type: A Positive	Worsen	2.42
Blood Type: O Positive	Improves	-2.59
Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grinding	Improves	-1.8
Comorbid-Mouth: Dry Mouth	Worsen	2.45
Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndrome	Improves	-1.62
Comorbid: Constipation and Explosions (not diarrohea)	Improves	-0.19
Comorbid: High Anxiety	Improves	-0.19
Comorbid: Histamine or Mast Cell issues	Improves	-2.35
Comorbid: Inflammatory bowel disease	Improves	-2.98
Comorbid: Methylation issues (MTHFR)	Worsen	2.83
Comorbid: Migraine	Worsen	1.86
Comorbid: Multiple Chemical Sensitivity	Worsen	2.9
Comorbid: Snoring (NOT Sleep Apnea	Improves	-1.79
Condition: ME/CFS with IBS	Worsen	2.8
DePaul University Fatigue Questionnaire : Abdomen pain	Worsen	2.8
DePaul University Fatigue Questionnaire : Allergies	Improves	-2.27
DePaul University Fatigue Questionnaire : Anxiety/tension	Worsen	2.97
DePaul University Fatigue Questionnaire : Depression	Worsen	3.73
DePaul University Fatigue Questionnaire : Difficulty falling asleep	Improves	-3.37
DePaul University Fatigue Questionnaire : Difficulty finding the right word	Worsen	2.2
DePaul University Fatigue Questionnaire : Fatigue	Worsen	3.18
DePaul University Fatigue Questionnaire : Forgetting what you are trying to say	Worsen	3.46
DePaul University Fatigue Questionnaire : Impaired Memory & concentration	Improves	-2.93
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired	Improves	-3.16
DePaul University Fatigue Questionnaire : Walking up early in the morning (e.g. 3AM)	Worsen	2.37
General: Fatigue	Worsen	2.9
General: Headaches	Improves	-1.62
General: Sinus issues with headaches	Improves	-1.8
Immune Manifestations: Alcohol Intolerant	Improves	-1.62
Immune Manifestations: Inflammation (General)	Improves	-3.37
Immune Manifestations: medication sensitivities.	Worsen	3.05
Immune Manifestations: Mucus in the stool	Improves	-2.92
Infection: Parasite - Other	Improves	-1.66
Joint: Stiffness and swelling	Improves	-1.7
Joint: Sudden and severe episodes of pain	Worsen	1.85
Joint: Tenderness	Improves	-1.85
Neurocognitive: Can only focus on one thing at a time	Improves	-1.7
Neuroendocrine Manifestations: Dry Eye (Sicca or Sjogren Syndrome)	Worsen	1.86
Neuroendocrine Manifestations: Excessive adrenaline	Worsen	3.52
Neuroendocrine Manifestations: intolerance of extremes of heat and cold	Worsen	3.09
Neuroendocrine Manifestations: Muscle weakness	Worsen	3.51
Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin)	Improves	-1.85
Neuroendocrine Manifestations: subnormal body temperature	Worsen	2.7
Neuroendocrine: Alcohol intolerance	Improves	-1.7
Neuroendocrine: Cold limbs (e.g. arms, legs hands)	Improves	-2.65
Neuroendocrine: Feeling like you have a low temperature	Worsen	3.61
Neuroendocrine: Lack of appetite	Worsen	0
Neuroendocrine: Lost or gained weight without trying	Worsen	3.65
Neurological-Audio: Tinnitus (ringing in ear)	Improves	-1.7
Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep)	Improves	-1.64
Neurological-Sleep: Sleep Apnea	Worsen	1.86
Neurological-Sleep: Vivid Dreams/Nightmares	Improves	-1.73
Neurological-Vision: inability to focus eye/vision	Improves	-1.8
Neurological: emotional overload	Worsen	2.74
Neurological: Executive Decision Making (Difficulty making)	Worsen	2.42
Neurological: fasciculations	Worsen	2.74
Neurological: High degree of Empathy before onset	Worsen	2.74
Neurological: Impairment of concentration	Worsen	2.42
Neurological: Joint hypermobility	Improves	-1.8
Neurological: Short-term memory issues	Worsen	2.47
Neurological: Slowed speech	Worsen	2.47
Neurological: Spatial instability and disorientation	Worsen	2.74
Neurological: Word-finding problems	Worsen	1.79
Official Diagnosis: Allergic Rhinitis (Hay Fever)	Improves	-2.93
Official Diagnosis: Chronic Fatigue Syndrome	Improves	-2.65
Official Diagnosis: Irritable Bowel Syndrome	Improves	-2.92
Official Diagnosis: Mast Cell Dysfunction	Improves	-2.35
Onset: Gradual	Improves	-2.65
Onset: less than 02 years since onset	Worsen	2.74
Other: Sensitivity to mold	Improves	-1.76
Other: Sensitivity to vibrations	Improves	-2.65
Pain: Sensitivity to pain	Improves	-1.8
Post-exertional malaise: Mentally tired after the slightest effort	Worsen	3.09
Post-exertional malaise: Worsening of symptoms after mild mental activity	Worsen	2.74
Sleep: Problems staying asleep	Improves	-1.7
Sleep: Waking up early in the morning (e.g. 3 AM)	Improves	-1.7

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

Symptom	Impact	Predictor of Bacteria Shift
Acne	Improves	-4.61
ADHD	Worsen	3.48
Allergic Rhinitis (Hay Fever)	Improves	-2.18
Allergies	Improves	-3.57
Alzheimer's disease	Improves	-5.1
Amyotrophic lateral sclerosis (ALS) Motor Neuron	Worsen	3.81
Ankylosing spondylitis	Worsen	5.17
Asthma	Worsen	3.13
Atherosclerosis	Worsen	4.25
Autism	Improves	-4.5
Barrett esophagus cancer	Improves	-4.64
Bipolar Disorder	Improves	-3.02
Brain Trauma	Worsen	3.46
Carcinoma	Improves	-2.93
Celiac Disease	Improves	-3.46
Cerebral Palsy	Worsen	1.55
Chronic Fatigue Syndrome	Improves	-3.88
Chronic Kidney Disease	Improves	-4.45
Chronic Lyme	Improves	-2.74
Chronic Urticaria (Hives)	Improves	-3.89
Colorectal Cancer	Improves	-4.37
Coronary artery disease	Improves	-3.52
COVID-19	Improves	-4.46
Crohn's Disease	Improves	-5.08
Depression	Improves	-3.34
Eczema	Improves	-5.28
Epilepsy	Improves	-4.02
Fibromyalgia	Improves	-4.42
Functional constipation / chronic idiopathic constipation	Worsen	2.25
gallstone disease (gsd)	Improves	-1.58
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus	Improves	-3.01
Generalized anxiety disorder	Improves	-4.55
Gout	Improves	-2.84
Graves' disease	Improves	-2.88
Hashimoto's thyroiditis	Improves	-2.86
High Blood Pressure	Improves	-3.68
Histamine Issues	Improves	-3.4
Histamine Issues From Ubiome	Improves	-2.96
hypercholesterolemia (High Cholesterol)	Improves	-2.76
Hyperlipidemia (High Blood Fats)	Improves	-4.38
hypertension (High Blood Pressure	Improves	-2.84
IgA nephropathy (IgAN)	Improves	-4.05
Inflammatory Bowel Disease	Improves	-5.56
Insomnia	Worsen	2.76
Irritable Bowel Syndrome	Improves	-5.62
Liver Cirrhosis	Worsen	1.51
ME/CFS with IBS	Improves	-2.77
ME/CFS without IBS	Worsen	2.03
Metabolic Syndrome	Improves	-1.09
Mood Disorders	Improves	-2.74
Multiple Sclerosis	Improves	-4.36
Multiple system atrophy (MSA)	Improves	-2.39
neuropsychiatric disorders (PANDAS, PANS)	Improves	-3.12
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic	Improves	-4.71
NonCeliac Gluten Sensitivity	Improves	-2.88
Obesity	Improves	-4.28
Osteoarthritis	Worsen	1
Osteoporosis	Worsen	3.48
Parkinson's Disease	Worsen	4.32
Psoriasis	Improves	-4.56
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	Improves	-5.53
Rosacea	Improves	-1.11
Schizophrenia	Worsen	4.64
Sjögren syndrome	Improves	-4.77
Small Intestinal Bacterial Overgrowth (SIBO)	Improves	-4.32
Stress / posttraumatic stress disorder	Improves	-4.98
Systemic Lupus Erythematosus	Improves	-4.99
Type 1 Diabetes	Improves	-4.47
Type 2 Diabetes	Worsen	3.69
Ulcerative colitis	Improves	-4.31

Bacteria Impacted

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.