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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomImpactPredictor of Bacteria Shift
Age: 20-30Worsen2.48
Autonomic Manifestations: cardiac arrhythmiasWorsen3.5
Comorbid: FibromyalgiaImproves-3.17
Neurological: Executive Decision Making (Difficulty making)Worsen2.42
Neurological: Impairment of concentrationWorsen2.42
Pain: Sensitivity to painImproves-2.31

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomImpactPredictor of Bacteria Shift
AcneImproves-2.42
Allergic Rhinitis (Hay Fever)Improves-2.41
AllergiesImproves-1.08
Amyotrophic lateral sclerosis (ALS) Motor NeuronImproves-2.61
Ankylosing spondylitisWorsen2.37
AsthmaWorsen2.21
AtherosclerosisImproves-4.62
AutismWorsen4.75
Barrett esophagus cancerWorsen2.83
Bipolar DisorderImproves-2.61
Brain TraumaWorsen2.48
CarcinomaImproves-3.98
Celiac DiseaseImproves-3.09
Cerebral PalsyImproves-2.83
Chronic Fatigue SyndromeImproves-2.86
Chronic Kidney DiseaseImproves-2.41
Chronic Urticaria (Hives)Improves-3.62
Colorectal CancerImproves-3.65
COVID-19Improves-3.88
Crohn's DiseaseImproves-4.03
cystic fibrosisImproves-3.57
DepressionImproves-2.5
EpilepsyImproves-2.83
FibromyalgiaWorsen3.49
Functional constipation / chronic idiopathic constipationImproves-2.63
Gastroesophageal reflux disease (Gerd) including Barrett's esophagusWorsen2.9
Generalized anxiety disorderImproves-3.45
Graves' diseaseImproves-3.62
Hashimoto's thyroiditisImproves-2.42
High Blood PressureWorsen2.69
Histamine IssuesImproves-3.52
hypercholesterolemia (High Cholesterol)Worsen2.69
Inflammatory Bowel DiseaseImproves-4.93
Irritable Bowel SyndromeImproves-3.29
Liver CirrhosisImproves-5.12
ME/CFS with IBSImproves-3.5
ME/CFS without IBSImproves-3.77
Multiple SclerosisImproves-4.49
Multiple system atrophy (MSA)Improves-2.32
neuropsychiatric disorders (PANDAS, PANS)Improves-2.42
Nonalcoholic Fatty Liver Disease (nafld) NonalcoholicImproves-4.47
NonCeliac Gluten SensitivityImproves-2.06
ObesityImproves-3.83
OsteoarthritisImproves-3.3
OsteoporosisImproves-2.41
Parkinson's DiseaseWorsen3.79
PsoriasisImproves-3.94
rheumatoid arthritis (RA),Spondyloarthritis (SpA)Improves-3.99
RosaceaWorsen2.69
SchizophreniaWorsen2.61
Sjögren syndromeImproves-3.76
Small Intestinal Bacterial Overgrowth (SIBO)Improves-4.38
Stress / posttraumatic stress disorderImproves-4.18
Systemic Lupus ErythematosusImproves-4.02
Type 1 DiabetesWorsen4.25
Type 2 DiabetesImproves-3.4
Ulcerative colitisImproves-4.26

Bacteria Impacted

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We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Pasteurellaceae family Decreases 📓 Source Study
Staphylococcaceae family Decreases 📓 Source Study
Streptococcaceae family Decreases 📓 Source Study
Escherichia genus Decreases 📓 Source Study
Haemophilus genus Decreases 📓 Source Study
Klebsiella genus Decreases 📓 Source Study
Kluyvera genus Decreases 📓 Source Study
Pseudomonas genus Decreases 📓 Source Study
Staphylococcus genus Decreases 📓 Source Study
Staphylococcus genus Decreases 📓 Source Study
Streptococcus genus Decreases 📓 Source Study
Actinobacillus genus Decreases 👪 Source Study
Aggregatibacter genus Decreases 👪 Source Study
Auricoccus genus Decreases 👪 Source Study
Avibacterium genus Decreases 👪 Source Study
Basfia genus Decreases 👪 Source Study
Bibersteinia genus Decreases 👪 Source Study
Bisgaardia genus Decreases 👪 Source Study
Gallibacterium genus Decreases 👪 Source Study
Glaesserella genus Decreases 👪 Source Study
Histophilus genus Decreases 👪 Source Study
Jeotgalicoccus genus Decreases 👪 Source Study
Lactovum genus Decreases 👪 Source Study
Macrococcus genus Decreases 👪 Source Study
Mannheimia genus Decreases 👪 Source Study
Necropsobacter genus Decreases 👪 Source Study
Nicoletella genus Decreases 👪 Source Study
Nosocomiicoccus genus Decreases 👪 Source Study
Otariodibacter genus Decreases 👪 Source Study
Pasteurella genus Decreases 👪 Source Study
Pseudomonas chlororaphis group genus Decreases 👪 Source Study
Rodentibacter genus Decreases 👪 Source Study
Salinicoccus genus Decreases 👪 Source Study
Ursidibacter genus Decreases 👪 Source Study
Volucribacter genus Decreases 👪 Source Study
[Clostridium] leptum species Decreases 📓 Source Study
[Eubacterium] cellulosolvens species Decreases 📓 Source Study
[Eubacterium] eligens species Decreases 📓 Source Study
Bacteroides fragilis species Decreases 📓 Source Study
CCUG 46150 species Decreases 📓 Source Study
Escherichia coli species Decreases 📓 Source Study
Eubacterium oxidoreducens species Decreases 📓 Source Study
Haemophilus influenzae species Decreases 📓 Source Study
Haemophilus parainfluenzae species Decreases 📓 Source Study
Pseudomonas aeruginosa species Decreases 📓 Source Study
Pseudomonas aeruginosa group species Decreases 📓 Source Study
Staphylococcus sp. 3348O2 species Decreases 📓 Source Study
Staphylococcus sp. C9I2 species Decreases 📓 Source Study
Streptococcus agalactiae species Decreases 📓 Source Study
Streptococcus australis species Decreases 📓 Source Study
Streptococcus dysgalactiae group species Decreases 📓 Source Study
Streptococcus gordonii species Decreases 📓 Source Study
Streptococcus peroris species Decreases 📓 Source Study
Streptococcus sp. 11aTha1 species Decreases 📓 Source Study
Streptococcus sp. 2011_Ileo_MS_A10 species Decreases 📓 Source Study
Streptococcus sp. 2011_Oral_MS_A3 species Decreases 📓 Source Study
Streptococcus sp. 3244O2 species Decreases 📓 Source Study
Streptococcus sp. BS35a species Decreases 📓 Source Study
Streptococcus sp. GMD6S species Decreases 📓 Source Study
Streptococcus sp. oral taxon G59 species Decreases 📓 Source Study
Streptococcus sp. S16-11 species Decreases 📓 Source Study
[Clostridium] spiroforme species Decreases 👪 Source Study
[Haemophilus] ducreyi species Decreases 👪 Source Study
Achromobacter georgiopolitanum species Decreases 👪 Source Study
ATCC 35469 species Decreases 👪 Source Study
ATCC 35538 species Decreases 👪 Source Study
ATCC 35539 species Decreases 👪 Source Study
ATCC 43138 species Decreases 👪 Source Study
ATCC 43808 species Decreases 👪 Source Study
ATCC 43809 species Decreases 👪 Source Study
ATCC 49168 species Decreases 👪 Source Study
ATCC 49171 species Decreases 👪 Source Study
ATCC 49910 species Decreases 👪 Source Study
ATCC 51365 species Decreases 👪 Source Study
ATCC 700337 species Decreases 👪 Source Study
ATCC 700373 species Decreases 👪 Source Study
CCM 7045 species Decreases 👪 Source Study
CCM 7213 species Decreases 👪 Source Study
CCUG 46149 species Decreases 👪 Source Study
CCUG 48363 species Decreases 👪 Source Study
CCUG 51270 species Decreases 👪 Source Study
CCUG 55896 species Decreases 👪 Source Study
CCUG 59809 species Decreases 👪 Source Study
CGMCC 1.15531 species Decreases 👪 Source Study
CGMCC 1.15532 species Decreases 👪 Source Study
CGMCC 1.15533 species Decreases 👪 Source Study
CGMCC 1.15534 species Decreases 👪 Source Study
CGMCC 1.15667 species Decreases 👪 Source Study
CIP 110771 species Decreases 👪 Source Study
DSM 104980 species Decreases 👪 Source Study
DSM 18963 species Decreases 👪 Source Study
DSM 26920 species Decreases 👪 Source Study
DSM 28299 species Decreases 👪 Source Study
DSM 28300 species Decreases 👪 Source Study
DSM 6978 species Decreases 👪 Source Study
Escherichia albertii species Decreases 👪 Source Study
Escherichia coli Biovare species Decreases 👪 Source Study
Escherichia marmotae species Decreases 👪 Source Study
Escherichia sp. species Decreases 👪 Source Study
Escherichia sp. 1_1_43 species Decreases 👪 Source Study
Escherichia sp. 4_1_40B species Decreases 👪 Source Study
Eubacterium uniforme species Decreases 👪 Source Study
fluorescent pseudomonads species Decreases 👪 Source Study
Haemophilus aegyptius species Decreases 👪 Source Study
Haemophilus haemoglobinophilus species Decreases 👪 Source Study
Haemophilus haemolyticus species Decreases 👪 Source Study
Haemophilus parahaemolyticus species Decreases 👪 Source Study
Haemophilus parainfluenzae species Decreases 👪 Source Study
Haemophilus paraphrohaemolyticus species Decreases 👪 Source Study
Haemophilus pittmaniae species Decreases 👪 Source Study
Haemophilus quentini Olsen et al. 2005 species Decreases 👪 Source Study
Haemophilus sp. species Decreases 👪 Source Study
Haemophilus sp. 11p18 species Decreases 👪 Source Study
Haemophilus sp. oral taxon 036 species Decreases 👪 Source Study
Haemophilus sp. oral taxon 851 species Decreases 👪 Source Study
Haemophilus sp. paraurethrae species Decreases 👪 Source Study
Haemophilus sputorum species Decreases 👪 Source Study
KCTC 32541 species Decreases 👪 Source Study
Klebsiella michiganensis species Decreases 👪 Source Study
Klebsiella sp. species Decreases 👪 Source Study
Klebsiella sp. B12 species Decreases 👪 Source Study
Klebsiella sp. FDAARGOS_511 species Decreases 👪 Source Study
Klebsiella sp. M5al species Decreases 👪 Source Study
Klebsiella sp. OBRC7 species Decreases 👪 Source Study
Klebsiella sp. SOR89 species Decreases 👪 Source Study
Klebsiella sp. WCHKl090001 species Decreases 👪 Source Study
Klebsiella variicola species Decreases 👪 Source Study
Kluyvera ascorbata species Decreases 👪 Source Study
Kluyvera cryocrescens species Decreases 👪 Source Study
Kluyvera georgiana species Decreases 👪 Source Study
Kluyvera intermedia species Decreases 👪 Source Study
Kluyvera sp. SR5.1 species Decreases 👪 Source Study
LTH 3734 species Decreases 👪 Source Study
Pseudomonas alcaligenes species Decreases 👪 Source Study
Pseudomonas arsenicoxydans species Decreases 👪 Source Study
Pseudomonas brassicacearum species Decreases 👪 Source Study
Pseudomonas citronellolis species Decreases 👪 Source Study
Pseudomonas denitrificans ATCC 13867 species Decreases 👪 Source Study
Pseudomonas entomophila species Decreases 👪 Source Study
Pseudomonas extremaustralis species Decreases 👪 Source Study
Pseudomonas frederiksbergensis species Decreases 👪 Source Study
Pseudomonas gingeri species Decreases 👪 Source Study
Pseudomonas graminis species Decreases 👪 Source Study
Pseudomonas granadensis species Decreases 👪 Source Study
Pseudomonas guangdongensis species Decreases 👪 Source Study
Pseudomonas koreensis species Decreases 👪 Source Study
Pseudomonas litoralis species Decreases 👪 Source Study
Pseudomonas mendocina species Decreases 👪 Source Study
Pseudomonas moraviensis species Decreases 👪 Source Study
Pseudomonas oryzae species Decreases 👪 Source Study
Pseudomonas parafulva species Decreases 👪 Source Study
Pseudomonas pohangensis species Decreases 👪 Source Study
Pseudomonas prosekii species Decreases 👪 Source Study
Pseudomonas psychrotolerans species Decreases 👪 Source Study
Pseudomonas putida group species Decreases 👪 Source Study
Pseudomonas reinekei species Decreases 👪 Source Study
Pseudomonas resinovorans species Decreases 👪 Source Study
Pseudomonas sabulinigri species Decreases 👪 Source Study
Pseudomonas salegens species Decreases 👪 Source Study
Pseudomonas saponiphila species Decreases 👪 Source Study
Pseudomonas saudiphocaensis species Decreases 👪 Source Study
Pseudomonas sihuiensis species Decreases 👪 Source Study
Pseudomonas soli species Decreases 👪 Source Study
Pseudomonas sp. 02C 26 species Decreases 👪 Source Study
Pseudomonas sp. 31-12 species Decreases 👪 Source Study
Pseudomonas sp. 7SR1 species Decreases 👪 Source Study
Pseudomonas sp. a101-18-2 species Decreases 👪 Source Study
Pseudomonas sp. a111-5 species Decreases 👪 Source Study
Pseudomonas sp. ACM7 species Decreases 👪 Source Study
Pseudomonas sp. CC6-YY-74 species Decreases 👪 Source Study
Pseudomonas sp. CMR12a species Decreases 👪 Source Study
Pseudomonas sp. CMR5c species Decreases 👪 Source Study
Pseudomonas sp. DQ-01 species Decreases 👪 Source Study
Pseudomonas sp. DTU12.3 species Decreases 👪 Source Study
Pseudomonas sp. DY-1 species Decreases 👪 Source Study
Pseudomonas sp. G1116 species Decreases 👪 Source Study
Pseudomonas sp. GmFRB023 species Decreases 👪 Source Study
Pseudomonas sp. KB23 species Decreases 👪 Source Study
Pseudomonas sp. KVS86 species Decreases 👪 Source Study
Pseudomonas sp. LH1G9 species Decreases 👪 Source Study
Pseudomonas sp. LPH1 species Decreases 👪 Source Study
Pseudomonas sp. LTJR-52 species Decreases 👪 Source Study
Pseudomonas sp. MFY143 species Decreases 👪 Source Study
Pseudomonas sp. MRSN12121 species Decreases 👪 Source Study
Pseudomonas sp. MT-1 species Decreases 👪 Source Study
Pseudomonas sp. NS1(2017) species Decreases 👪 Source Study
Pseudomonas sp. PcFRB072 species Decreases 👪 Source Study
Pseudomonas sp. PcFRB119 species Decreases 👪 Source Study
Pseudomonas sp. PONIH3 species Decreases 👪 Source Study
Pseudomonas sp. ps4-2 species Decreases 👪 Source Study
Pseudomonas sp. QZS01 species Decreases 👪 Source Study
Pseudomonas sp. R4-34-07 species Decreases 👪 Source Study
Pseudomonas sp. R5-89-07 species Decreases 👪 Source Study
Pseudomonas sp. RU47 species Decreases 👪 Source Study
Pseudomonas sp. S-6-2 species Decreases 👪 Source Study
Pseudomonas sp. StFLB209 species Decreases 👪 Source Study
Pseudomonas sp. SWI36 species Decreases 👪 Source Study
Pseudomonas sp. TCU-HL1 species Decreases 👪 Source Study
Pseudomonas sp. TMW 2.1634 species Decreases 👪 Source Study
Pseudomonas sp. URMO17WK12:I11 species Decreases 👪 Source Study
Pseudomonas sp. WCS374 species Decreases 👪 Source Study
Pseudomonas straminea species Decreases 👪 Source Study
Pseudomonas stutzeri group species Decreases 👪 Source Study
Pseudomonas syringae group species Decreases 👪 Source Study
Pseudomonas umsongensis species Decreases 👪 Source Study
Pseudomonas versuta species Decreases 👪 Source Study
Pseudomonas xinjiangensis species Decreases 👪 Source Study
Pseudomonas yamanorum species Decreases 👪 Source Study
Staphylococcus auricularis species Decreases 👪 Source Study
Staphylococcus capitis species Decreases 👪 Source Study
Staphylococcus chromogenes species Decreases 👪 Source Study
Staphylococcus cohnii species Decreases 👪 Source Study
Staphylococcus devriesei species Decreases 👪 Source Study
Staphylococcus equorum species Decreases 👪 Source Study
Staphylococcus haemolyticus species Decreases 👪 Source Study
Staphylococcus pasteuri species Decreases 👪 Source Study
Staphylococcus piscifermentans species Decreases 👪 Source Study
Staphylococcus saprophyticus species Decreases 👪 Source Study
Staphylococcus sciuri species Decreases 👪 Source Study
Staphylococcus simulans species Decreases 👪 Source Study
Staphylococcus sp. 3035O2 species Decreases 👪 Source Study
Staphylococcus sp. 3356O2 species Decreases 👪 Source Study
Staphylococcus sp. FXY54 species Decreases 👪 Source Study
Staphylococcus sp. L10 species Decreases 👪 Source Study
Staphylococcus sp. M0911 species Decreases 👪 Source Study
Staphylococcus sp. SDB 2975 species Decreases 👪 Source Study
Staphylococcus sp. WB17-17 species Decreases 👪 Source Study
Staphylococcus sp. WB18-16 species Decreases 👪 Source Study
Staphylococcus stepanovicii species Decreases 👪 Source Study
Staphylococcus vitulinus species Decreases 👪 Source Study
Staphylococcus warneri species Decreases 👪 Source Study
Staphylococcus xylosus species Decreases 👪 Source Study
Streptococcus acidominimus species Decreases 👪 Source Study
Streptococcus anginosus group species Decreases 👪 Source Study
Streptococcus canis species Decreases 👪 Source Study
Streptococcus cristatus species Decreases 👪 Source Study
Streptococcus danieliae species Decreases 👪 Source Study
Streptococcus dentapri species Decreases 👪 Source Study
Streptococcus dentasini species Decreases 👪 Source Study
Streptococcus didelphis species Decreases 👪 Source Study
Streptococcus dysgalactiae species Decreases 👪 Source Study
Streptococcus entericus species Decreases 👪 Source Study
Streptococcus equi species Decreases 👪 Source Study
Streptococcus G418 species Decreases 👪 Source Study
Streptococcus gallolyticus species Decreases 👪 Source Study
Streptococcus hyointestinalis species Decreases 👪 Source Study
Streptococcus hyovaginalis species Decreases 👪 Source Study
Streptococcus infantarius species Decreases 👪 Source Study
Streptococcus infantis species Decreases 👪 Source Study
Streptococcus iniae species Decreases 👪 Source Study
Streptococcus marimammalium species Decreases 👪 Source Study
Streptococcus massiliensis species Decreases 👪 Source Study
Streptococcus merionis species Decreases 👪 Source Study
Streptococcus milleri species Decreases 👪 Source Study
Streptococcus mitis species Decreases 👪 Source Study
Streptococcus oralis species Decreases 👪 Source Study
Streptococcus orisasini species Decreases 👪 Source Study
Streptococcus orisratti species Decreases 👪 Source Study
Streptococcus parauberis species Decreases 👪 Source Study
Streptococcus pharyngis species Decreases 👪 Source Study
Streptococcus phocae species Decreases 👪 Source Study
Streptococcus pluranimalium species Decreases 👪 Source Study
Streptococcus plurextorum species Decreases 👪 Source Study
Streptococcus porcorum species Decreases 👪 Source Study
Streptococcus pseudopneumoniae species Decreases 👪 Source Study
Streptococcus pseudoporcinus species Decreases 👪 Source Study
Streptococcus rupicaprae species Decreases 👪 Source Study
Streptococcus sanguinis species Decreases 👪 Source Study
Streptococcus seminale species Decreases 👪 Source Study
Streptococcus sobrinus species Decreases 👪 Source Study
Streptococcus sp. 2_1_36FAA species Decreases 👪 Source Study
Streptococcus sp. 2011_Ileo_MS_A12 species Decreases 👪 Source Study
Streptococcus sp. 2011_Ileo_MS_C3 species Decreases 👪 Source Study
Streptococcus sp. 2011_Oral_MS_B3 species Decreases 👪 Source Study
Streptococcus sp. 2011_Oral_MS_D12 species Decreases 👪 Source Study
Streptococcus sp. 2011_Oral_MS_E1 species Decreases 👪 Source Study
Streptococcus sp. A12 species Decreases 👪 Source Study
Streptococcus sp. AS14 species Decreases 👪 Source Study
Streptococcus sp. BS35b species Decreases 👪 Source Study
Streptococcus sp. canine oral taxon 279 species Decreases 👪 Source Study
Streptococcus sp. F0441 species Decreases 👪 Source Study
Streptococcus sp. F0442 species Decreases 👪 Source Study
Streptococcus sp. FDAARGOS_192 species Decreases 👪 Source Study
Streptococcus sp. HPA1 species Decreases 👪 Source Study
Streptococcus sp. HPH0090 species Decreases 👪 Source Study
Streptococcus sp. HSISB1 species Decreases 👪 Source Study
Streptococcus sp. HSISM1 species Decreases 👪 Source Study
Streptococcus sp. HSISS1 species Decreases 👪 Source Study
Streptococcus sp. HSISS2 species Decreases 👪 Source Study
Streptococcus sp. I-G2 species Decreases 👪 Source Study
Streptococcus sp. JS71 species Decreases 👪 Source Study
Streptococcus sp. M143 species Decreases 👪 Source Study
Streptococcus sp. NPS 308 species Decreases 👪 Source Study
Streptococcus sp. oral taxon 064 species Decreases 👪 Source Study
Streptococcus sp. oral taxon 071 species Decreases 👪 Source Study
Streptococcus sp. oral taxon 431 species Decreases 👪 Source Study
Streptococcus sp. oral taxon G62 species Decreases 👪 Source Study
Streptococcus sp. oral taxon G63 species Decreases 👪 Source Study
Streptococcus sp. S16-08 species Decreases 👪 Source Study
Streptococcus sp. TM013 species Decreases 👪 Source Study
Streptococcus sp. Z15 species Decreases 👪 Source Study
Streptococcus suis species Decreases 👪 Source Study
Streptococcus troglodytae species Decreases 👪 Source Study
Streptococcus troglodytidis species Decreases 👪 Source Study
Streptococcus uberis species Decreases 👪 Source Study
Streptococcus urinalis species Decreases 👪 Source Study
Streptococcus vestibularis species Decreases 👪 Source Study
Streptococcus viridans species Decreases 👪 Source Study

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