azithromycin,(antibiotic)s ** full range

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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

Symptom	Impact	Predictor of Bacteria Shift
Age: 0-10	Worsen	1.91
Age: 20-30	Worsen	3.28
Age: 60-70	Worsen	3.31
Autism: Official Diagnosis	Improves	-3.38
Autonomic Manifestations: cardiac arrhythmias	Improves	-2.75
Autonomic Manifestations: Cortisol disorders or irregularity	Worsen	1.7
Autonomic Manifestations: irritable bowel syndrome	Worsen	2.39
Autonomic Manifestations: Orthostatic intolerance	Worsen	1.79
Autonomic Manifestations: palpitations	Worsen	3.59
Autonomic: Graying or blacking out after standing	Worsen	2.92
Autonomic: Heart rate increase after standing	Worsen	3.21
Autonomic: Shortness of breath	Improves	-2.84
Blood Type: A Positive	Improves	-2.42
Blood Type: O Positive	Improves	-0.3
Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grinding	Worsen	2.39
Comorbid-Mouth: Dry Mouth	Worsen	3.05
Comorbid-Mouth: Gingivits / Gum Disease	Worsen	2.27
Comorbid-Mouth: Mouth Sores	Worsen	2.56
Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndrome	Worsen	1.62
Comorbid: Constipation and Diarrohea (not explosions)	Improves	-2.93
Comorbid: Constipation and Explosions (not diarrohea)	Worsen	3.67
Comorbid: High Anxiety	Worsen	1.8
Comorbid: Histamine or Mast Cell issues	Worsen	3
Comorbid: Inflammatory bowel disease	Improves	-3.3
Comorbid: Migraine	Improves	-3.16
Comorbid: Mold Sensitivity / Exposure	Worsen	1.82
Comorbid: Multiple Chemical Sensitivity	Worsen	3.55
Comorbid: Snoring (NOT Sleep Apnea	Worsen	2.38
Condition: ME/CFS with IBS	Improves	-2.8
DePaul University Fatigue Questionnaire : Abdomen pain	Improves	-3.95
DePaul University Fatigue Questionnaire : Allergies	Improves	-3.54
DePaul University Fatigue Questionnaire : Anxiety/tension	Improves	-4.04
DePaul University Fatigue Questionnaire : Depression	Improves	-3.98
DePaul University Fatigue Questionnaire : Difficulty falling asleep	Improves	-3.66
DePaul University Fatigue Questionnaire : Difficulty finding the right word	Improves	-3.57
DePaul University Fatigue Questionnaire : Difficulty staying asleep	Improves	-3.59
DePaul University Fatigue Questionnaire : Fatigue	Improves	-4.48
DePaul University Fatigue Questionnaire : Forgetting what you are trying to say	Improves	-3.95
DePaul University Fatigue Questionnaire : Impaired Memory & concentration	Improves	-4.14
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired	Improves	-4.23
DePaul University Fatigue Questionnaire : Walking up early in the morning (e.g. 3AM)	Improves	-3.87
Gender: Female	Improves	-2.92
General: Fatigue	Worsen	3.55
General: Headaches	Worsen	2.7
Immune Manifestations: Abdominal Pain	Worsen	2.48
Immune Manifestations: Alcohol Intolerant	Worsen	2.7
Immune Manifestations: Bloating	Worsen	3.32
Immune Manifestations: Constipation	Worsen	3.32
Immune Manifestations: general malaise	Worsen	2.39
Infection: Epstein-Barr virus	Improves	-1.83
Infection: Human Herpesvirus 6 (HHV6)	Worsen	1.75
Joint: Stiffness and swelling	Worsen	2.73
Neurocognitive: Absent-mindedness or forgetfulness	Worsen	2.39
Neurocognitive: Brain Fog	Worsen	2.39
Neurocognitive: Can only focus on one thing at a time	Worsen	2.73
Neurocognitive: Slowness of thought	Worsen	3.08
Neurocognitive: Unable to focus vision and/or attention	Worsen	2.56
Neuroendocrine Manifestations: Excessive adrenaline	Improves	-2.63
Neuroendocrine Manifestations: intolerance of extremes of heat and cold	Worsen	3.43
Neuroendocrine Manifestations: Muscle weakness	Worsen	4.21
Neuroendocrine Manifestations: subnormal body temperature	Worsen	2.39
Neuroendocrine Manifestations: sweating episodes	Improves	-3.2
Neuroendocrine Manifestations: worsening of symptoms with stress.	Worsen	2.69
Neuroendocrine: Alcohol intolerance	Worsen	2.73
Neuroendocrine: Cold limbs (e.g. arms, legs hands)	Worsen	3.27
Neuroendocrine: Feeling like you have a low temperature	Worsen	3.11
Neuroendocrine: Lack of appetite	Worsen	2.87
Neuroendocrine: Lost or gained weight without trying	Worsen	3.65
Neurological-Audio: hypersensitivity to noise	Worsen	2.39
Neurological-Audio: Tinnitus (ringing in ear)	Worsen	1.7
Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep)	Worsen	3.3
Neurological-Sleep: Vivid Dreams/Nightmares	Worsen	1.73
Neurological-Vision: Blurred Vision	Worsen	3.59
Neurological-Vision: inability to focus eye/vision	Worsen	3.68
Neurological: Confusion	Worsen	2.63
Neurological: Difficulty processing information (Understanding)	Worsen	3.12
Neurological: Difficulty reading	Worsen	2.39
Neurological: emotional overload	Worsen	3.12
Neurological: Executive Decision Making (Difficulty making)	Worsen	2.71
Neurological: fasciculations	Worsen	3.71
Neurological: High degree of Empathy before onset	Worsen	0
Neurological: Impairment of concentration	Worsen	3.22
Neurological: Joint hypermobility	Improves	-1.83
Neurological: Short-term memory issues	Worsen	3.27
Neurological: Slowed speech	Worsen	2.99
Neurological: Spatial instability and disorientation	Worsen	0
Neurological: Word-finding problems	Worsen	1.79
Official Diagnosis: Allergic Rhinitis (Hay Fever)	Worsen	2.38
Official Diagnosis: Chronic Fatigue Syndrome	Worsen	1.53
Official Diagnosis: Irritable Bowel Syndrome	Worsen	2.39
Official Diagnosis: Mast Cell Dysfunction	Worsen	2.73
Onset: 2010-2020	Worsen	3.32
Onset: Gradual	Worsen	3.58
Onset: less than 02 years since onset	Worsen	0
Other: Sensitivity to mold	Worsen	1.76
Other: Sensitivity to vibrations	Worsen	1.53
Pain: Myofascial pain	Worsen	1.53
Pain: Sensitivity to pain	Improves	-1.83
Post-exertional malaise: Mentally tired after the slightest effort	Improves	-1.13
Post-exertional malaise: Worsening of symptoms after mild mental activity	Worsen	0
Sleep: Daytime drowsiness	Worsen	3.32
Sleep: Problems staying asleep	Worsen	3.47
Sleep: Waking up early in the morning (e.g. 3 AM)	Worsen	2.73

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

Symptom	Impact	Predictor of Bacteria Shift
Acne	Improves	-2.01
ADHD	Improves	-3.51
Allergic Rhinitis (Hay Fever)	Improves	-3.19
Allergies	Worsen	4.53
Alzheimer's disease	Improves	-4.76
Amyotrophic lateral sclerosis (ALS) Motor Neuron	Improves	-3.18
Ankylosing spondylitis	Improves	-4.41
Asthma	Improves	-1.18
Atherosclerosis	Improves	-5.03
Autism	Improves	-3.84
Barrett esophagus cancer	Improves	-1.75
Bipolar Disorder	Improves	-2.9
Brain Trauma	Worsen	2.93
Carcinoma	Worsen	1.59
Celiac Disease	Worsen	4.5
Cerebral Palsy	Worsen	2.98
Chronic Fatigue Syndrome	Worsen	3.33
Chronic Kidney Disease	Worsen	2.97
Chronic Lyme	Worsen	0
Chronic Urticaria (Hives)	Worsen	2.15
Colorectal Cancer	Improves	-5.56
Coronary artery disease	Worsen	3.16
COVID-19	Improves	-0.1
Crohn's Disease	Improves	-4.47
cystic fibrosis	Improves	-2.21
Depression	Improves	-3.62
Epilepsy	Worsen	2.82
Fibromyalgia	Improves	-2.84
Functional constipation / chronic idiopathic constipation	Worsen	3.91
gallstone disease (gsd)	Improves	-3.07
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus	Improves	-4.26
Generalized anxiety disorder	Improves	-3.89
Gout	Worsen	2.84
Graves' disease	Improves	-3.31
Hashimoto's thyroiditis	Worsen	3.23
High Blood Pressure	Worsen	3.66
Histamine Issues	Improves	-2.94
Histamine Issues From Ubiome	Worsen	2.96
hypercholesterolemia (High Cholesterol)	Worsen	1.03
Hyperlipidemia (High Blood Fats)	Worsen	3.3
hypertension (High Blood Pressure	Improves	-3.68
IgA nephropathy (IgAN)	Worsen	3.87
Inflammatory Bowel Disease	Worsen	3.91
Insomnia	Worsen	2.76
Irritable Bowel Syndrome	Improves	-5.21
Liver Cirrhosis	Worsen	3
ME/CFS with IBS	Worsen	0.69
ME/CFS without IBS	Improves	-1.15
Metabolic Syndrome	Worsen	2.47
Mood Disorders	Improves	-2.97
Multiple Sclerosis	Improves	-3.94
Multiple system atrophy (MSA)	Improves	-3.49
neuropsychiatric disorders (PANDAS, PANS)	Improves	-2.82
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic	Worsen	5
NonCeliac Gluten Sensitivity	Improves	-2.06
Obesity	Worsen	2.64
Osteoarthritis	Improves	-2.51
Osteoporosis	Improves	-4.13
Parkinson's Disease	Improves	-5.74
Psoriasis	Improves	-2.1
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	Improves	-4.36
Rosacea	Worsen	3.07
Schizophrenia	Improves	-4.98
Sjögren syndrome	Worsen	1.82
Small Intestinal Bacterial Overgrowth (SIBO)	Improves	-2.67
Stress / posttraumatic stress disorder	Improves	-4.21
Systemic Lupus Erythematosus	Worsen	4.42
Type 1 Diabetes	Worsen	3.67
Type 2 Diabetes	Improves	-3.76
Ulcerative colitis	Worsen	4.11

Bacteria Impacted

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.