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Citizen Science Infered Impact

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomFrequency FoundRelative Impact
Age: 0-10Improves-5.98
Age: 20-30Worsen3.97
Age: 40-50Improves-7.41
Age: 60-70Worsen7.64
Asymptomatic: No Health IssuesImproves-3.22
Autonomic Manifestations: irritable bowel syndromeImproves-4.11
Autonomic Manifestations: Orthostatic intoleranceWorsen6.54
Autonomic: Blurred or tunnel vision after standingImproves-6.78
Autonomic: Graying or blacking out after standingImproves-6.78
Autonomic: Heart rate increase after standingWorsen6.43
Autonomic: Irregular heartbeatsWorsen4.69
Autonomic: Shortness of breathImproves-4.48
Blood Type: A PositiveImproves-5.81
Blood Type: O PositiveWorsen6.89
Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grindingWorsen7.58
Comorbid-Mouth: Mouth SoresWorsen3.61
Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndromeWorsen7.66
Comorbid: Constipation and Explosions (not diarrohea)Improves-8.05
Comorbid: High AnxietyWorsen4.01
Comorbid: Histamine or Mast Cell issuesImproves-7.52
Comorbid: HypothyroidismWorsen7.83
Comorbid: Inflammatory bowel disease Improves-8.03
Comorbid: Methylation issues (MTHFR)Worsen2.83
Comorbid: MigraineImproves-7.95
Comorbid: Restless LegWorsen4.23
Comorbid: Small intestinal bacterial overgrowth (SIBO)Worsen6.93
Comorbid: Snoring (NOT Sleep ApneaWorsen6.93
DePaul University Fatigue Questionnaire : FatigueImproves-7.28
DePaul University Fatigue Questionnaire : Impaired Memory & concentrationImproves-8.63
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired Improves-7.14
Gender: FemaleImproves-6.78
Gender: MaleImproves-1.14
General: DepressionWorsen4.41
General: HeadachesWorsen4.89
General: Heavy feeling in arms and legsImproves-4.31
General: Myalgia (pain)Improves-4.94
Immune Manifestations: Abdominal PainWorsen7.54
Immune Manifestations: Alcohol IntolerantWorsen2.95
Immune Manifestations: BloatingImproves-3.42
Immune Manifestations: ConstipationWorsen7.72
Immune Manifestations: DiarrheaWorsen5.55
Immune Manifestations: general malaiseWorsen7.55
Immune Manifestations: Hair lossWorsen4.41
Immune Manifestations: Inflammation (General)Improves-6.55
Immune Manifestations: Inflammation of skin, eyes or jointsImproves-6.81
Immune Manifestations: medication sensitivities.Improves-5.06
Immune Manifestations: Mucus in the stoolWorsen7.66
Immune Manifestations: tender lymph nodesImproves-4.86
Immune: Tender / sore lymph nodesImproves-6.78
Infection: Epstein-Barr virusImproves-6.14
Infection: Parasite - OtherImproves-6.62
Joint: RednessWorsen5.52
Joint: Stiffness and swellingWorsen5.73
Joint: TendernessWorsen7.88
Neurocognitive: Absent-mindedness or forgetfulnessWorsen7.63
Neurocognitive: Brain FogWorsen7.8
Neurocognitive: Can only focus on one thing at a timeImproves-4.67
Neurocognitive: Difficulty paying attention for a long period of timeWorsen7.6
Neurocognitive: Problems remembering thingsWorsen7.61
Neurocognitive: Slowness of thoughtImproves-3.71
Neurocognitive: Unable to focus vision and/or attentionWorsen7.65
Neuroendocrine Manifestations: marked weight change Improves-0.34
Neuroendocrine Manifestations: Muscle weakness Improves-2.75
Neuroendocrine Manifestations: NeuralgiaImproves-7.86
Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin)Improves-3.19
Neuroendocrine Manifestations: subnormal body temperatureWorsen7.6
Neuroendocrine Manifestations: sweating episodesWorsen4.36
Neuroendocrine Manifestations: worsening of symptoms with stress.Worsen3.37
Neuroendocrine: Alcohol intoleranceWorsen7.25
Neuroendocrine: Cold limbs (e.g. arms, legs hands)Worsen4.41
Neuroendocrine: Feeling hot or cold for no reasonWorsen2.83
Neuroendocrine: Feeling like you have a high temperatureWorsen4.23
Neuroendocrine: Feeling like you have a low temperatureWorsen7.86
Neuroendocrine: Temperature fluctuations throughout the dayWorsen3.84
Neurological-Audio: hypersensitivity to noiseWorsen7.62
Neurological-Audio: Tinnitus (ringing in ear)Worsen8.16
Neurological-Sleep: Chaotic diurnal sleep rhythms (Irratic Sleep)Worsen7.59
Neurological-Sleep: InsomniaWorsen1.69
Neurological-Sleep: Night SweatsImproves-4.81
Neurological-Sleep: Sleep ApneaWorsen5.21
Neurological-Vision: inability to focus eye/visionWorsen7.62
Neurological-Vision: photophobia (Light Sensitibity)Worsen6.92
Neurological: Cognitive OverloadImproves-4.7
Neurological: Difficulty readingWorsen7.47
Neurological: DysautonomiaWorsen8.56
Neurological: Executive Decision Making (Difficulty making)Improves-5.94
Neurological: fasciculations Worsen7.5
Neurological: Impairment of concentrationImproves-3.5
Neurological: Joint hypermobilityImproves-6.88
Neurological: Slowed speechWorsen5.29
Neurological: Word-finding problemsWorsen3.57
Official Diagnosis: Allergic Rhinitis (Hay Fever)Improves-6.5
Official Diagnosis: Autoimmune DiseaseImproves-3.97
Official Diagnosis: Chronic Fatigue SyndromeWorsen3.92
Official Diagnosis: FibromyalgiaWorsen4.09
Official Diagnosis: Irritable Bowel SyndromeImproves-7.06
Official Diagnosis: Mast Cell DysfunctionImproves-7.54
Onset: 2010-2020Worsen6.94
Onset: less than 02 years since onsetWorsen4.46
Onset: less than 32 years since onsetImproves-4.56
Other: Sensitivity to moldImproves-7.23
Pain: Aching of the eyes or behind the eyesImproves-6.78
Pain: Myofascial painImproves-2.59
Post-exertional malaise: Muscle fatigue after mild physical activityWorsen5.54
Post-exertional malaise: Next-day soreness after everyday activitiesImproves-6.85
Post-exertional malaise: Physically tired after minimum exerciseWorsen4.08
Post-exertional malaise: Rapid cognitive fatigability, Worsen7.5
Post-exertional malaise: Worsening of symptoms after mild mental activityWorsen7.5
Post-exertional malaise: Worsening of symptoms after mild physical activityWorsen4.47
Sleep: Daytime drowsinessWorsen7.57
Sleep: Problems staying asleepWorsen7.72
Sleep: Waking up early in the morning (e.g. 3 AM)Worsen6.76

Published Science Infered Impact

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomFrequency FoundRelative Impact
Allergic Rhinitis (Hay Fever)Improves-3.24
Alzheimer's diseaseWorsen8.76
Amyotrophic lateral sclerosis (ALS) Motor NeuronWorsen6.78
Ankylosing spondylitisWorsen9.22
Autoimmune DiseaseImproves-3.29
Barrett esophagus cancerImproves-6.03
Brain TraumaImproves-6.89
Celiac DiseaseImproves-6.81
Chronic Fatigue SyndromeImproves-7.4
Chronic Kidney DiseaseImproves-7.56
Chronic urticaria (Hives)Improves-8.55
Colorectal CancerImproves-10.61
Crohn's DiseaseImproves-7.72
cystic fibrosisImproves-7.49
Functional constipation / chronic idiopathic constipationImproves-8.2
Gastro-esophageal reflux disease (Gerd) including Barrett's esophagusWorsen7.3
Generalized anxiety disorderImproves-8.69
Graves' diseaseWorsen6.97
Hashimoto's thyroiditisImproves-7.8
High Blood PressureWorsen8.63
Histamine IssuesImproves-8.9
Histamine Issues From UbiomeWorsen6.01
hypercholesterolemia (High Cholesterol)Improves-7.01
IgA nephropathy (IgAN)Worsen8.52
Inflammatory Bowel DiseaseImproves-9.04
Irritable Bowel SyndromeImproves-8.93
Juvenile idiopathic arthritisWorsen5.45
Liver CirrhosisWorsen5.21
ME/CFS with IBSImproves-8.5
ME/CFS without IBSImproves-9.27
Metabolic SyndromeWorsen7.16
Mood DisordersImproves-7.57
Multiple SclerosisImproves-8.86
neuropsychiatric disorders (PANDAS, PANS)Improves-8.02
Non-alcoholic Fatty Liver Disease (nafld) NonalcoholicImproves-6.8
Non-Celiac Gluten SensitivityWorsen1.35
Parkinson's DiseaseImproves-8.14
Rheumatoid arthritisWorsen8.56
rheumatoid arthritis (RA) and Spondyloarthritis (SpA)Improves-8.43
Sjögren syndromeImproves-8.4
Small Intestinal Bacterial Overgrowth (SIBO)Improves-8.7
Stress / post-traumatic stress disorderImproves-9.85
Systemic Lupus ErythematosusImproves-8.95
Type 1 DiabetesImproves-7.25
Type 2 DiabetesWorsen9.27
Ulcerative colitisWorsen8.39

Bacteria Impacted

Suggest a missed study:

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Actinobacillus genus Decreases 📓 Source Study
Citrobacter genus Increases 📓 Source Study
Actinobacillus arthritidis species Decreases 👪 Source Study
Actinobacillus delphinicola species Decreases 👪 Source Study
Actinobacillus pleuropneumoniae species Decreases 👪 Source Study
Actinobacillus porcinus species Decreases 👪 Source Study
Actinobacillus porcitonsillarum species Decreases 👪 Source Study
Actinobacillus scotiae species Decreases 👪 Source Study
Actinobacillus succinogenes species Decreases 👪 Source Study
Actinobacillus suis species Decreases 👪 Source Study
DSM 5568 species Decreases 👪 Source Study
Prevotella sp. 109 species Decreases 👪 Source Study
ATCC 51112 species Increases 👪 Source Study
Citrobacter amalonaticus species Increases 👪 Source Study
Citrobacter sp. species Increases 👪 Source Study
Citrobacter sp. BW4 species Increases 👪 Source Study
Citrobacter sp. HD4.9 species Increases 👪 Source Study
JCM 1658 species Increases 👪 Source Study