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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomImpactPredictor of Bacteria Shift
Age: 20-30Worsen2.48
Age: 60-70Worsen2.56
Autonomic Manifestations: cardiac arrhythmiasWorsen3.5
Comorbid-Mouth: Mouth SoresWorsen2.56
Comorbid: Constipation and Explosions (not diarrohea)Worsen2.56
DePaul University Fatigue Questionnaire : Difficulty falling asleepImproves-2.85
DePaul University Fatigue Questionnaire : Difficulty finding the right wordImproves-2.85
Neurocognitive: Slowness of thoughtWorsen2.48
Neurocognitive: Unable to focus vision and/or attentionWorsen2.56
Neuroendocrine: Feeling like you have a low temperatureWorsen2.74
Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep)Worsen2.56
Neurological-Vision: inability to focus eye/visionWorsen2.56
Neurological: emotional overloadWorsen2.74
Neurological: Executive Decision Making (Difficulty making)Worsen2.42
Neurological: fasciculations Worsen2.74
Neurological: High degree of Empathy before onsetWorsen2.74
Neurological: Impairment of concentrationWorsen2.42
Neurological: Short-term memory issuesWorsen2.74
Neurological: Spatial instability and disorientationWorsen2.74
Onset: less than 02 years since onsetWorsen2.74
Post-exertional malaise: Worsening of symptoms after mild mental activityWorsen2.74

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomImpactPredictor of Bacteria Shift
AcneImproves-2.42
Allergic Rhinitis (Hay Fever)Improves-2.41
AllergiesWorsen2.61
Amyotrophic lateral sclerosis (ALS) Motor NeuronImproves-2.41
Ankylosing spondylitisImproves-2.81
AsthmaWorsen0
AtherosclerosisImproves-4.5
AutismWorsen4.57
Barrett esophagus cancerWorsen2.83
Bipolar DisorderImproves-3.18
Brain TraumaImproves-1.53
CarcinomaImproves-3.69
Celiac DiseaseImproves-3.09
Cerebral PalsyImproves-2.83
Chronic Fatigue SyndromeImproves-3.4
Chronic Kidney DiseaseImproves-2.41
Chronic LymeImproves-2.74
Chronic Urticaria (Hives)Improves-3.62
Colorectal CancerImproves-3.56
COVID-19Improves-3.96
Crohn's DiseaseImproves-4.22
DepressionImproves-4.01
EczemaImproves-3.66
EpilepsyImproves-2.83
Functional constipation / chronic idiopathic constipationImproves-2.63
Gastroesophageal reflux disease (Gerd) including Barrett's esophagusWorsen3.46
Generalized anxiety disorderImproves-3.45
Graves' diseaseWorsen2.74
High Blood PressureWorsen0
Histamine IssuesImproves-2.77
IgA nephropathy (IgAN)Improves-2.74
Inflammatory Bowel DiseaseImproves-4.85
Irritable Bowel SyndromeImproves-3.57
Liver CirrhosisImproves-4.11
ME/CFS with IBSImproves-3.5
ME/CFS without IBSImproves-3.5
Mood DisordersImproves-2.74
Multiple SclerosisImproves-2.83
neuropsychiatric disorders (PANDAS, PANS)Improves-2.42
Nonalcoholic Fatty Liver Disease (nafld) NonalcoholicImproves-4.86
ObesityImproves-4.03
OsteoarthritisImproves-3.3
OsteoporosisImproves-2.41
Parkinson's DiseaseImproves-2.72
PsoriasisImproves-3.94
rheumatoid arthritis (RA),Spondyloarthritis (SpA)Improves-4.45
SchizophreniaImproves-0.16
Sjögren syndromeImproves-3.76
Small Intestinal Bacterial Overgrowth (SIBO)Improves-4.11
Stress / posttraumatic stress disorderImproves-4.55
Systemic Lupus ErythematosusImproves-4.26
Type 1 DiabetesWorsen3.36
Type 2 DiabetesImproves-4.38
Ulcerative colitisImproves-4.67

Bacteria Impacted

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We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Bacillaceae family Decreases 📓 Source Study
Enterobacteriaceae family Decreases 📓 Source Study
Staphylococcaceae family Decreases 📓 Source Study
Staphylococcaceae family Decreases 📓 Source Study
Streptococcaceae family Decreases 📓 Source Study
Streptococcaceae family Decreases 📓 Source Study
Bacillus genus Decreases 📓 Source Study
Escherichia genus Decreases 📓 Source Study
Klebsiella genus Decreases 📓 Source Study
Kluyvera genus Decreases 📓 Source Study
Staphylococcus genus Decreases 📓 Source Study
Staphylococcus genus Decreases 📓 Source Study
Streptococcus genus Decreases 📓 Source Study
Streptococcus genus Decreases 📓 Source Study
Aeribacillus genus Decreases 👪 Source Study
Amphibacillus genus Decreases 👪 Source Study
Anaerobacillus genus Decreases 👪 Source Study
Anoxybacillus genus Decreases 👪 Source Study
Atlantibacter genus Decreases 👪 Source Study
Auricoccus genus Decreases 👪 Source Study
Bacillus altitudinis complex genus Decreases 👪 Source Study
Biostraticola genus Decreases 👪 Source Study
Buttiauxella genus Decreases 👪 Source Study
Caldalkalibacillus genus Decreases 👪 Source Study
Candidatus Ishikawaella genus Decreases 👪 Source Study
Candidatus Moranella genus Decreases 👪 Source Study
Candidatus Riesia genus Decreases 👪 Source Study
Cedecea genus Decreases 👪 Source Study
Fictibacillus genus Decreases 👪 Source Study
Geobacillus genus Decreases 👪 Source Study
Gibbsiella genus Decreases 👪 Source Study
Gracilibacillus genus Decreases 👪 Source Study
Halobacillus genus Decreases 👪 Source Study
Halolactibacillus genus Decreases 👪 Source Study
Hydrogenibacillus genus Decreases 👪 Source Study
Jeotgalicoccus genus Decreases 👪 Source Study
Kosakonia genus Decreases 👪 Source Study
Lactovum genus Decreases 👪 Source Study
Leclercia genus Decreases 👪 Source Study
Lelliottia genus Decreases 👪 Source Study
Lentibacillus genus Decreases 👪 Source Study
Limnobaculum genus Decreases 👪 Source Study
Lysinibacillus genus Decreases 👪 Source Study
Macrococcus genus Decreases 👪 Source Study
Marinococcus genus Decreases 👪 Source Study
Metakosakonia genus Decreases 👪 Source Study
Microaerobacter genus Decreases 👪 Source Study
Nosocomiicoccus genus Decreases 👪 Source Study
Oceanobacillus genus Decreases 👪 Source Study
Parageobacillus genus Decreases 👪 Source Study
Paraliobacillus genus Decreases 👪 Source Study
Pluralibacter genus Decreases 👪 Source Study
Pontibacillus genus Decreases 👪 Source Study
Pseudescherichia genus Decreases 👪 Source Study
Psychrobacillus genus Decreases 👪 Source Study
Quasibacillus genus Decreases 👪 Source Study
Raoultella genus Decreases 👪 Source Study
Rosenbergiella genus Decreases 👪 Source Study
Salimicrobium genus Decreases 👪 Source Study
Salinibacillus genus Decreases 👪 Source Study
Salinicoccus genus Decreases 👪 Source Study
Shimwellia genus Decreases 👪 Source Study
Siccibacter genus Decreases 👪 Source Study
Sinibacillus genus Decreases 👪 Source Study
Tepidibacillus genus Decreases 👪 Source Study
Terribacillus genus Decreases 👪 Source Study
Texcoconibacillus genus Decreases 👪 Source Study
Thermolongibacillus genus Decreases 👪 Source Study
Virgibacillus genus Decreases 👪 Source Study
Yokenella genus Decreases 👪 Source Study
[Clostridium] leptum species Decreases 📓 Source Study
[Clostridium] leptum species Decreases 📓 Source Study
Escherichia coli species Decreases 📓 Source Study
Streptococcus agalactiae species Decreases 📓 Source Study
Streptococcus agalactiae species Decreases 📓 Source Study
[Brevibacterium] frigoritolerans species Decreases 👪 Source Study
[Clostridium] spiroforme species Decreases 👪 Source Study
ATCC 35469 species Decreases 👪 Source Study
ATCC 35538 species Decreases 👪 Source Study
ATCC 35539 species Decreases 👪 Source Study
ATCC 43138 species Decreases 👪 Source Study
ATCC 43808 species Decreases 👪 Source Study
ATCC 43809 species Decreases 👪 Source Study
ATCC 49168 species Decreases 👪 Source Study
ATCC 49171 species Decreases 👪 Source Study
ATCC 49910 species Decreases 👪 Source Study
ATCC 51365 species Decreases 👪 Source Study
ATCC 700337 species Decreases 👪 Source Study
ATCC 700373 species Decreases 👪 Source Study
ATCC BAA-1126 species Decreases 👪 Source Study
Bacillus aeolius species Decreases 👪 Source Study
Bacillus alcaliinulinus species Decreases 👪 Source Study
Bacillus asahii species Decreases 👪 Source Study
Bacillus aurantiacus species Decreases 👪 Source Study
Bacillus berkeleyi species Decreases 👪 Source Study
Bacillus beveridgei species Decreases 👪 Source Study
Bacillus butanolivorans species Decreases 👪 Source Study
Bacillus canaveralius species Decreases 👪 Source Study
Bacillus cecembensis species Decreases 👪 Source Study
Bacillus cellulosilyticus species Decreases 👪 Source Study
Bacillus chagannorensis species Decreases 👪 Source Study
Bacillus circulans species Decreases 👪 Source Study
Bacillus clausii species Decreases 👪 Source Study
Bacillus coagulans species Decreases 👪 Source Study
Bacillus cohnii species Decreases 👪 Source Study
Bacillus filamentosus species Decreases 👪 Source Study
Bacillus flexus species Decreases 👪 Source Study
Bacillus foraminis species Decreases 👪 Source Study
Bacillus fordii species Decreases 👪 Source Study
Bacillus funiculus species Decreases 👪 Source Study
Bacillus glycinifermentans species Decreases 👪 Source Study
Bacillus gobiensis species Decreases 👪 Source Study
Bacillus halodurans species Decreases 👪 Source Study
Bacillus horti species Decreases 👪 Source Study
Bacillus infantis species Decreases 👪 Source Study
Bacillus infernus species Decreases 👪 Source Study
Bacillus kochii species Decreases 👪 Source Study
Bacillus krulwichiae species Decreases 👪 Source Study
Bacillus lehensis species Decreases 👪 Source Study
Bacillus lentus species Decreases 👪 Source Study
Bacillus litoralis species Decreases 👪 Source Study
Bacillus luteus species Decreases 👪 Source Study
Bacillus marisflavi species Decreases 👪 Source Study
Bacillus marmarensis species Decreases 👪 Source Study
Bacillus megaterium species Decreases 👪 Source Study
Bacillus mesonae species Decreases 👪 Source Study
Bacillus methanolicus species Decreases 👪 Source Study
Bacillus muralis species Decreases 👪 Source Study
Bacillus nanhaiisediminis species Decreases 👪 Source Study
Bacillus oceanisediminis species Decreases 👪 Source Study
Bacillus okuhidensis species Decreases 👪 Source Study
Bacillus oleronius species Decreases 👪 Source Study
Bacillus oshimensis species Decreases 👪 Source Study
Bacillus pseudalcaliphilus species Decreases 👪 Source Study
Bacillus pseudofirmus species Decreases 👪 Source Study
Bacillus psychrosaccharolyticus species Decreases 👪 Source Study
Bacillus pumilus species Decreases 👪 Source Study
Bacillus rhizosphaerae species Decreases 👪 Source Study
Bacillus simplex species Decreases 👪 Source Study
Bacillus smithii species Decreases 👪 Source Study
Bacillus sp. species Decreases 👪 Source Study
Bacillus sp. 1NLA3E species Decreases 👪 Source Study
Bacillus sp. 2+3 species Decreases 👪 Source Study
Bacillus sp. BT1B_CT2 species Decreases 👪 Source Study
Bacillus sp. CZb species Decreases 👪 Source Study
Bacillus sp. DHT-33 species Decreases 👪 Source Study
Bacillus sp. DU-106 species Decreases 👪 Source Study
Bacillus sp. FJAT-18017 species Decreases 👪 Source Study
Bacillus sp. FJAT-22090 species Decreases 👪 Source Study
Bacillus sp. FJAT-42376 species Decreases 👪 Source Study
Bacillus sp. FJAT-45348 species Decreases 👪 Source Study
Bacillus sp. HC15 species Decreases 👪 Source Study
Bacillus sp. HYC-10 species Decreases 👪 Source Study
Bacillus sp. IHB B 7164 species Decreases 👪 Source Study
Bacillus sp. Lzh-5 species Decreases 👪 Source Study
Bacillus sp. N-16 species Decreases 👪 Source Study
Bacillus sp. NCIM2463 species Decreases 👪 Source Study
Bacillus sp. Pc3 species Decreases 👪 Source Study
Bacillus sp. PrMC7 species Decreases 👪 Source Study
Bacillus sp. SgZ-7 species Decreases 👪 Source Study
Bacillus sp. SYJ species Decreases 👪 Source Study
Bacillus sp. T41 species Decreases 👪 Source Study
Bacillus sp. WP8 species Decreases 👪 Source Study
Bacillus sp. X1(2014) species Decreases 👪 Source Study
Bacillus sp. Y1 species Decreases 👪 Source Study
Bacillus thermoamyloliquefaciens species Decreases 👪 Source Study
Bacillus thermoamylovorans species Decreases 👪 Source Study
Bacillus tianmuensis species Decreases 👪 Source Study
Bacillus weihaiensis species Decreases 👪 Source Study
CCM 7045 species Decreases 👪 Source Study
CCM 7213 species Decreases 👪 Source Study
CCUG 46149 species Decreases 👪 Source Study
CCUG 48363 species Decreases 👪 Source Study
CCUG 51270 species Decreases 👪 Source Study
CCUG 55896 species Decreases 👪 Source Study
CCUG 59809 species Decreases 👪 Source Study
CGMCC 1.15531 species Decreases 👪 Source Study
CGMCC 1.15532 species Decreases 👪 Source Study
CGMCC 1.15533 species Decreases 👪 Source Study
CGMCC 1.15534 species Decreases 👪 Source Study
CGMCC 1.15667 species Decreases 👪 Source Study
CIP 110771 species Decreases 👪 Source Study
DSM 104980 species Decreases 👪 Source Study
DSM 18963 species Decreases 👪 Source Study
DSM 26920 species Decreases 👪 Source Study
DSM 28299 species Decreases 👪 Source Study
DSM 28300 species Decreases 👪 Source Study
Escherichia albertii species Decreases 👪 Source Study
Escherichia coli Biovare species Decreases 👪 Source Study
Escherichia marmotae species Decreases 👪 Source Study
Escherichia sp. species Decreases 👪 Source Study
Escherichia sp. 1_1_43 species Decreases 👪 Source Study
Escherichia sp. 4_1_40B species Decreases 👪 Source Study
Eubacterium uniforme species Decreases 👪 Source Study
Klebsiella michiganensis species Decreases 👪 Source Study
Klebsiella sp. species Decreases 👪 Source Study
Klebsiella sp. B12 species Decreases 👪 Source Study
Klebsiella sp. FDAARGOS_511 species Decreases 👪 Source Study
Klebsiella sp. M5al species Decreases 👪 Source Study
Klebsiella sp. OBRC7 species Decreases 👪 Source Study
Klebsiella sp. SOR89 species Decreases 👪 Source Study
Klebsiella sp. WCHKl090001 species Decreases 👪 Source Study
Klebsiella variicola species Decreases 👪 Source Study
Kluyvera ascorbata species Decreases 👪 Source Study
Kluyvera cryocrescens species Decreases 👪 Source Study
Kluyvera georgiana species Decreases 👪 Source Study
Kluyvera intermedia species Decreases 👪 Source Study
Kluyvera sp. SR5.1 species Decreases 👪 Source Study
LTH 3734 species Decreases 👪 Source Study
Staphylococcus auricularis species Decreases 👪 Source Study
Staphylococcus capitis species Decreases 👪 Source Study
Staphylococcus chromogenes species Decreases 👪 Source Study
Staphylococcus cohnii species Decreases 👪 Source Study
Staphylococcus devriesei species Decreases 👪 Source Study
Staphylococcus equorum species Decreases 👪 Source Study
Staphylococcus haemolyticus species Decreases 👪 Source Study
Staphylococcus pasteuri species Decreases 👪 Source Study
Staphylococcus piscifermentans species Decreases 👪 Source Study
Staphylococcus saprophyticus species Decreases 👪 Source Study
Staphylococcus sciuri species Decreases 👪 Source Study
Staphylococcus simulans species Decreases 👪 Source Study
Staphylococcus sp. 3035O2 species Decreases 👪 Source Study
Staphylococcus sp. 3356O2 species Decreases 👪 Source Study
Staphylococcus sp. FXY54 species Decreases 👪 Source Study
Staphylococcus sp. L10 species Decreases 👪 Source Study
Staphylococcus sp. M0911 species Decreases 👪 Source Study
Staphylococcus sp. SDB 2975 species Decreases 👪 Source Study
Staphylococcus sp. WB17-17 species Decreases 👪 Source Study
Staphylococcus sp. WB18-16 species Decreases 👪 Source Study
Staphylococcus stepanovicii species Decreases 👪 Source Study
Staphylococcus vitulinus species Decreases 👪 Source Study
Staphylococcus warneri species Decreases 👪 Source Study
Staphylococcus xylosus species Decreases 👪 Source Study
Streptococcus acidominimus species Decreases 👪 Source Study
Streptococcus anginosus group species Decreases 👪 Source Study
Streptococcus canis species Decreases 👪 Source Study
Streptococcus cristatus species Decreases 👪 Source Study
Streptococcus danieliae species Decreases 👪 Source Study
Streptococcus dentapri species Decreases 👪 Source Study
Streptococcus dentasini species Decreases 👪 Source Study
Streptococcus didelphis species Decreases 👪 Source Study
Streptococcus entericus species Decreases 👪 Source Study
Streptococcus G418 species Decreases 👪 Source Study
Streptococcus gallolyticus species Decreases 👪 Source Study
Streptococcus hyointestinalis species Decreases 👪 Source Study
Streptococcus hyovaginalis species Decreases 👪 Source Study
Streptococcus infantarius species Decreases 👪 Source Study
Streptococcus infantis species Decreases 👪 Source Study
Streptococcus iniae species Decreases 👪 Source Study
Streptococcus marimammalium species Decreases 👪 Source Study
Streptococcus massiliensis species Decreases 👪 Source Study
Streptococcus merionis species Decreases 👪 Source Study
Streptococcus milleri species Decreases 👪 Source Study
Streptococcus mitis species Decreases 👪 Source Study
Streptococcus oralis species Decreases 👪 Source Study
Streptococcus orisasini species Decreases 👪 Source Study
Streptococcus orisratti species Decreases 👪 Source Study
Streptococcus parauberis species Decreases 👪 Source Study
Streptococcus pharyngis species Decreases 👪 Source Study
Streptococcus phocae species Decreases 👪 Source Study
Streptococcus pluranimalium species Decreases 👪 Source Study
Streptococcus plurextorum species Decreases 👪 Source Study
Streptococcus porcorum species Decreases 👪 Source Study
Streptococcus pseudopneumoniae species Decreases 👪 Source Study
Streptococcus pseudoporcinus species Decreases 👪 Source Study
Streptococcus rupicaprae species Decreases 👪 Source Study
Streptococcus sanguinis species Decreases 👪 Source Study
Streptococcus seminale species Decreases 👪 Source Study
Streptococcus sobrinus species Decreases 👪 Source Study
Streptococcus sp. 2_1_36FAA species Decreases 👪 Source Study
Streptococcus sp. 2011_Ileo_MS_A12 species Decreases 👪 Source Study
Streptococcus sp. 2011_Ileo_MS_C3 species Decreases 👪 Source Study
Streptococcus sp. 2011_Oral_MS_B3 species Decreases 👪 Source Study
Streptococcus sp. 2011_Oral_MS_D12 species Decreases 👪 Source Study
Streptococcus sp. 2011_Oral_MS_E1 species Decreases 👪 Source Study
Streptococcus sp. A12 species Decreases 👪 Source Study
Streptococcus sp. AS14 species Decreases 👪 Source Study
Streptococcus sp. BS35b species Decreases 👪 Source Study
Streptococcus sp. canine oral taxon 279 species Decreases 👪 Source Study
Streptococcus sp. F0441 species Decreases 👪 Source Study
Streptococcus sp. F0442 species Decreases 👪 Source Study
Streptococcus sp. FDAARGOS_192 species Decreases 👪 Source Study
Streptococcus sp. HPA1 species Decreases 👪 Source Study
Streptococcus sp. HPH0090 species Decreases 👪 Source Study
Streptococcus sp. HSISB1 species Decreases 👪 Source Study
Streptococcus sp. HSISM1 species Decreases 👪 Source Study
Streptococcus sp. HSISS1 species Decreases 👪 Source Study
Streptococcus sp. HSISS2 species Decreases 👪 Source Study
Streptococcus sp. I-G2 species Decreases 👪 Source Study
Streptococcus sp. JS71 species Decreases 👪 Source Study
Streptococcus sp. M143 species Decreases 👪 Source Study
Streptococcus sp. NPS 308 species Decreases 👪 Source Study
Streptococcus sp. oral taxon 064 species Decreases 👪 Source Study
Streptococcus sp. oral taxon 071 species Decreases 👪 Source Study
Streptococcus sp. oral taxon 431 species Decreases 👪 Source Study
Streptococcus sp. oral taxon G62 species Decreases 👪 Source Study
Streptococcus sp. oral taxon G63 species Decreases 👪 Source Study
Streptococcus sp. S16-08 species Decreases 👪 Source Study
Streptococcus sp. TM013 species Decreases 👪 Source Study
Streptococcus sp. Z15 species Decreases 👪 Source Study
Streptococcus suis species Decreases 👪 Source Study
Streptococcus troglodytae species Decreases 👪 Source Study
Streptococcus troglodytidis species Decreases 👪 Source Study
Streptococcus uberis species Decreases 👪 Source Study
Streptococcus urinalis species Decreases 👪 Source Study
Streptococcus vestibularis species Decreases 👪 Source Study
Streptococcus viridans species Decreases 👪 Source Study

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