We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Age: 20-30 | Worsen | 2.48 |
Asymptomatic: Minor Health Issues (a few symptoms only) | Improves | -1.85 |
Asymptomatic: No Health Issues | Improves | -1.6 |
Autism: Official Diagnosis | Worsen | 1.76 |
Autonomic: Graying or blacking out after standing | Improves | -1.76 |
Autonomic: Inability to tolerate an upright position | Worsen | 3.17 |
Blood Type: A Positive | Worsen | 2.42 |
Blood Type: O Positive | Worsen | 3.52 |
Comorbid-Mouth: Dry Mouth | Worsen | 2.37 |
Comorbid: Constipation and Explosions (not diarrohea) | Worsen | 2.38 |
Comorbid: High Anxiety | Worsen | 3.16 |
Comorbid: Histamine or Mast Cell issues | Worsen | 2.95 |
Comorbid: Inflammatory bowel disease | Worsen | 3.4 |
Comorbid: Migraine | Worsen | 3.38 |
Comorbid: Snoring (NOT Sleep Apnea | Worsen | 1.8 |
DePaul University Fatigue Questionnaire : Allergies | Worsen | 3.53 |
DePaul University Fatigue Questionnaire : Anxiety/tension | Worsen | 2.8 |
DePaul University Fatigue Questionnaire : Fatigue | Worsen | 3.89 |
DePaul University Fatigue Questionnaire : Forgetting what you are trying to say | Worsen | 3.51 |
DePaul University Fatigue Questionnaire : Impaired Memory & concentration | Worsen | 3.52 |
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired | Worsen | 3.52 |
DePaul University Fatigue Questionnaire : Walking up early in the morning (e.g. 3AM) | Worsen | 2.92 |
General: Headaches | Improves | -1.62 |
General: Sinus issues with headaches | Worsen | 1.8 |
Immune Manifestations: Abdominal Pain | Worsen | 2.48 |
Immune Manifestations: Diarrhea | Worsen | 1.93 |
Immune Manifestations: Inflammation (General) | Worsen | 3.87 |
Immune Manifestations: Mucus in the stool | Worsen | 2.92 |
Immune Manifestations: tender lymph nodes | Improves | -2.9 |
Immune: Tender / sore lymph nodes | Worsen | 2.88 |
Infection: Human Herpesvirus 6 (HHV6) | Worsen | 1.76 |
Joint: Stiffness and swelling | Worsen | 0.46 |
Joint: Sudden and severe episodes of pain | Improves | -1.85 |
Joint: Tenderness | Worsen | 1.85 |
Neurocognitive: Can only focus on one thing at a time | Worsen | 3.47 |
Neurocognitive: Slowness of thought | Worsen | 2.48 |
Neuroendocrine Manifestations: Excessive adrenaline | Worsen | 2.63 |
Neuroendocrine Manifestations: intolerance of extremes of heat and cold | Worsen | 1.58 |
Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin) | Worsen | 3.17 |
Neuroendocrine Manifestations: worsening of symptoms with stress. | Worsen | 3.47 |
Neuroendocrine: Alcohol intolerance | Worsen | 3.32 |
Neuroendocrine: Feeling like you have a low temperature | Worsen | 2.74 |
Neurological-Vision: inability to focus eye/vision | Worsen | 1.8 |
Neurological: Cognitive/Sensory Overload | Improves | -1.64 |
Neurological: emotional overload | Worsen | 2.74 |
Neurological: Executive Decision Making (Difficulty making) | Worsen | 2.42 |
Neurological: fasciculations | Worsen | 2.74 |
Neurological: High degree of Empathy before onset | Worsen | 2.74 |
Neurological: Joint hypermobility | Worsen | 1.8 |
Neurological: Short-term memory issues | Worsen | 2.47 |
Neurological: Slowed speech | Improves | -1.61 |
Neurological: Spatial instability and disorientation | Worsen | 2.74 |
Official Diagnosis: Allergic Rhinitis (Hay Fever) | Worsen | 3.35 |
Official Diagnosis: Autoimmune Disease | Worsen | 3.61 |
Official Diagnosis: Irritable Bowel Syndrome | Worsen | 3.16 |
Official Diagnosis: Mast Cell Dysfunction | Worsen | 0.47 |
Onset: Gradual | Improves | -1.95 |
Pain: Sensitivity to pain | Worsen | 1.8 |
Post-exertional malaise: General | Worsen | 2.74 |
Post-exertional malaise: Mentally tired after the slightest effort | Worsen | 3.48 |
Post-exertional malaise: Physically drained or sick after mild activity | Worsen | 2.74 |
Post-exertional malaise: Post-exertional malaise | Worsen | 2.74 |
Post-exertional malaise: Rapid cognitive fatigability, | Worsen | 2.74 |
Post-exertional malaise: Rapid muscular fatigability, | Worsen | 1.63 |
Post-exertional malaise: Worsening of symptoms after mild mental activity | Worsen | 2.74 |
Sleep: Problems staying asleep | Improves | -1.7 |
We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is according to the microbiome shifts reported in studies. Clinical studies may show different results
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Acne | Improves | -3.47 |
ADHD | Worsen | 3.56 |
Allergies | Improves | -2.98 |
Alzheimer's disease | Improves | -4.48 |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | Worsen | 2.48 |
Ankylosing spondylitis | Worsen | 4.92 |
Asthma | Worsen | 3.9 |
Atherosclerosis | Improves | -3.98 |
Autism | Improves | -3.63 |
Barrett esophagus cancer | Improves | -2.15 |
Brain Trauma | Improves | -2.32 |
Carcinoma | Improves | -3.18 |
Celiac Disease | Improves | -3.66 |
Chronic Fatigue Syndrome | Improves | -4.49 |
Chronic Kidney Disease | Improves | -3.61 |
Chronic urticaria (Hives) | Improves | -2.11 |
Colorectal Cancer | Worsen | 3.04 |
Coronary artery disease | Improves | -2.95 |
Crohn's Disease | Improves | -4.49 |
cystic fibrosis | Improves | -3.57 |
Depression | Improves | -2.88 |
Epilepsy | Improves | -3.78 |
Fibromyalgia | Improves | -3.9 |
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | Improves | -2.72 |
Generalized anxiety disorder | Improves | -4.4 |
Graves' disease | Worsen | 2.74 |
Hashimoto's thyroiditis | Improves | -3.48 |
High Blood Pressure | Improves | -3.09 |
Histamine Issues | Improves | -4.49 |
Histamine Issues From Ubiome | Improves | -2.96 |
Hyperlipidemia (High Blood Fats) | Improves | -2.63 |
IgA nephropathy (IgAN) | Improves | -3.95 |
Inflammatory Bowel Disease | Improves | -5.04 |
Irritable Bowel Syndrome | Improves | -4.84 |
Liver Cirrhosis | Improves | -4.82 |
ME/CFS with IBS | Worsen | 0.26 |
ME/CFS without IBS | Worsen | 3.03 |
Mood Disorders | Improves | -2.74 |
Multiple Sclerosis | Improves | -2.94 |
Multiple system atrophy (MSA) | Improves | -1.3 |
neuropsychiatric disorders (PANDAS, PANS) | Improves | -2.42 |
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | Improves | -1.37 |
Obesity | Worsen | 2.22 |
Osteoporosis | Worsen | 2.55 |
Parkinson's Disease | Worsen | 4.62 |
Psoriasis | Worsen | 2.14 |
Rheumatoid arthritis | Improves | -4.63 |
rheumatoid arthritis (RA),Spondyloarthritis (SpA) | Improves | -3.2 |
Rosacea | Improves | -2.26 |
Schizophrenia | Worsen | 3.78 |
Sclerosis | Improves | -3.37 |
Sjögren syndrome | Improves | -3.62 |
Small Intestinal Bacterial Overgrowth (SIBO) | Improves | -4.54 |
Stress / posttraumatic stress disorder | Improves | -4.72 |
Systemic Lupus Erythematosus | Improves | -2.81 |
Type 1 Diabetes | Improves | -2.22 |
Type 2 Diabetes | Improves | -4.53 |
Ulcerative colitis | Improves | -3.73 |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.