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    Citizen Science Infered Impact

    We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

    This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

    SymptomImpactPredictor of Bacteria Shift
    Comorbid-Mouth: Mouth SoresWorsen2.48
    Immune Manifestations: Abdominal PainWorsen2.48
    Neurocognitive: Slowness of thoughtWorsen2.48
    Neuroendocrine Manifestations: worsening of symptoms with stress.Worsen2.48

    Published Science Infered Impact

    We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

    This is according to the microbiome shifts reported in studies. Clinical studies may show different results

    SymptomImpactPredictor of Bacteria Shift
    AllergiesWorsen2.23
    Ankylosing spondylitisWorsen2.44
    AsthmaWorsen0
    AtherosclerosisImproves-2.85
    AutismWorsen0.19
    Celiac DiseaseImproves-2.48
    Chronic Fatigue SyndromeImproves-2.43
    Colorectal CancerWorsen3.04
    Crohn's DiseaseImproves-3.87
    cystic fibrosisImproves-3.57
    EpilepsyImproves-2.54
    Generalized anxiety disorderImproves-2.54
    High Blood PressureWorsen2.54
    Histamine IssuesImproves-3.53
    IgA nephropathy (IgAN)Worsen2.54
    Inflammatory Bowel DiseaseImproves-4.22
    Irritable Bowel SyndromeWorsen1.69
    Liver CirrhosisWorsen3.25
    ME/CFS with IBSWorsen0
    ME/CFS without IBSImproves-2.43
    Multiple SclerosisImproves-3.08
    ObesityWorsen2.48
    PsoriasisImproves-3.04
    Rheumatoid arthritisImproves-2.25
    rheumatoid arthritis (RA),Spondyloarthritis (SpA)Improves-3.53
    Small Intestinal Bacterial Overgrowth (SIBO)Improves-3.76
    Stress / posttraumatic stress disorderImproves-4.38
    Type 1 DiabetesWorsen2.48
    Type 2 DiabetesImproves-1.09
    Ulcerative colitisImproves-2.54

    Bacteria Impacted

    Suggest a missed study:

    We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

    📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
    Taxonomy Rank Effect Citations
    Bacillus genus Decreases 📓 Source Study
    Enterococcus genus Decreases 📓 Source Study
    Pseudomonas genus Decreases 📓 Source Study
    Salmonella genus Decreases 📓 Source Study
    Staphylococcus genus Decreases 📓 Source Study
    Yersinia genus Decreases 📓 Source Study
    Bacillus altitudinis complex genus Decreases 👪 Source Study
    Pseudomonas chlororaphis group genus Decreases 👪 Source Study
    Bacillus cereus species Decreases 📓 Source Study
    Bacillus cereus group species Decreases 📓 Source Study
    Enterococcus faecalis species Decreases 📓 Source Study
    Pseudomonas aeruginosa species Decreases 📓 Source Study
    Pseudomonas aeruginosa group species Decreases 📓 Source Study
    Staphylococcus aureus species Decreases 📓 Source Study
    Yersinia enterocolitica species Decreases 📓 Source Study
    [Brevibacterium] frigoritolerans species Decreases 👪 Source Study
    [Clostridium] spiroforme species Decreases 👪 Source Study
    Achromobacter georgiopolitanum species Decreases 👪 Source Study
    anthrax species Decreases 👪 Source Study
    Arthrobacter sp. BDR2P1B1-M species Decreases 👪 Source Study
    ATCC 13674 species Decreases 👪 Source Study
    ATCC 14235 species Decreases 👪 Source Study
    ATCC 27836 species Decreases 👪 Source Study
    ATCC 27848 species Decreases 👪 Source Study
    ATCC 29062 species Decreases 👪 Source Study
    ATCC 29909 species Decreases 👪 Source Study
    ATCC 29974 species Decreases 👪 Source Study
    ATCC 33641 species Decreases 👪 Source Study
    ATCC 35236 species Decreases 👪 Source Study
    ATCC 35538 species Decreases 👪 Source Study
    ATCC 35539 species Decreases 👪 Source Study
    ATCC 43380 species Decreases 👪 Source Study
    ATCC 43808 species Decreases 👪 Source Study
    ATCC 43809 species Decreases 👪 Source Study
    ATCC 43958 species Decreases 👪 Source Study
    ATCC 43975 species Decreases 👪 Source Study
    ATCC 49095 species Decreases 👪 Source Study
    ATCC 49168 species Decreases 👪 Source Study
    ATCC 49171 species Decreases 👪 Source Study
    ATCC 49372 species Decreases 👪 Source Study
    ATCC 49427 species Decreases 👪 Source Study
    ATCC 49910 species Decreases 👪 Source Study
    ATCC 51227 species Decreases 👪 Source Study
    ATCC 51266 species Decreases 👪 Source Study
    ATCC 51365 species Decreases 👪 Source Study
    ATCC 6462 species Decreases 👪 Source Study
    ATCC 700337 species Decreases 👪 Source Study
    ATCC 700373 species Decreases 👪 Source Study
    ATCC BAA-1126 species Decreases 👪 Source Study
    ATCC BAA-1240 species Decreases 👪 Source Study
    ATCC BAA-257 species Decreases 👪 Source Study
    ATCC BAA-350 species Decreases 👪 Source Study
    Bacillus aeolius species Decreases 👪 Source Study
    Bacillus albus species Decreases 👪 Source Study
    Bacillus alcaliinulinus species Decreases 👪 Source Study
    Bacillus asahii species Decreases 👪 Source Study
    Bacillus aurantiacus species Decreases 👪 Source Study
    Bacillus berkeleyi species Decreases 👪 Source Study
    Bacillus beveridgei species Decreases 👪 Source Study
    Bacillus butanolivorans species Decreases 👪 Source Study
    Bacillus canaveralius species Decreases 👪 Source Study
    Bacillus cecembensis species Decreases 👪 Source Study
    Bacillus cellulosilyticus species Decreases 👪 Source Study
    Bacillus chagannorensis species Decreases 👪 Source Study
    Bacillus circulans species Decreases 👪 Source Study
    Bacillus clausii species Decreases 👪 Source Study
    Bacillus coagulans species Decreases 👪 Source Study
    Bacillus filamentosus species Decreases 👪 Source Study
    Bacillus foraminis species Decreases 👪 Source Study
    Bacillus fordii species Decreases 👪 Source Study
    Bacillus fresconis species Decreases 👪 Source Study
    Bacillus funiculus species Decreases 👪 Source Study
    Bacillus glycinifermentans species Decreases 👪 Source Study
    Bacillus gobiensis species Decreases 👪 Source Study
    Bacillus halodurans species Decreases 👪 Source Study
    Bacillus horti species Decreases 👪 Source Study
    Bacillus infantis species Decreases 👪 Source Study
    Bacillus infernus species Decreases 👪 Source Study
    Bacillus kochii species Decreases 👪 Source Study
    Bacillus krulwichiae species Decreases 👪 Source Study
    Bacillus lehensis species Decreases 👪 Source Study
    Bacillus lentus species Decreases 👪 Source Study
    Bacillus litoralis species Decreases 👪 Source Study
    Bacillus luteus species Decreases 👪 Source Study
    Bacillus marmarensis species Decreases 👪 Source Study
    Bacillus megaterium species Decreases 👪 Source Study
    Bacillus mesonae species Decreases 👪 Source Study
    Bacillus methanolicus species Decreases 👪 Source Study
    Bacillus nanhaiisediminis species Decreases 👪 Source Study
    Bacillus oceanisediminis species Decreases 👪 Source Study
    Bacillus okuhidaensis species Decreases 👪 Source Study
    Bacillus oleronius species Decreases 👪 Source Study
    Bacillus oshimae species Decreases 👪 Source Study
    Bacillus pseudalcalophilus Nielsen et al. 1995 species Decreases 👪 Source Study
    Bacillus pseudofirmus species Decreases 👪 Source Study
    Bacillus pseudomycoides species Decreases 👪 Source Study
    Bacillus psychrosaccharolyticus species Decreases 👪 Source Study
    Bacillus pumilus species Decreases 👪 Source Study
    Bacillus rhizosphaerae species Decreases 👪 Source Study
    Bacillus simplex species Decreases 👪 Source Study
    Bacillus smithii species Decreases 👪 Source Study
    Bacillus sp. species Decreases 👪 Source Study
    Bacillus sp. 1NLA3E species Decreases 👪 Source Study
    Bacillus sp. 2+3 species Decreases 👪 Source Study
    Bacillus sp. ABP14 species Decreases 👪 Source Study
    Bacillus sp. BT1B_CT2 species Decreases 👪 Source Study
    Bacillus sp. CZb species Decreases 👪 Source Study
    Bacillus sp. DHT-33 species Decreases 👪 Source Study
    Bacillus sp. DU-106 species Decreases 👪 Source Study
    Bacillus sp. FJAT-18017 species Decreases 👪 Source Study
    Bacillus sp. FJAT-22090 species Decreases 👪 Source Study
    Bacillus sp. FJAT-42376 species Decreases 👪 Source Study
    Bacillus sp. FJAT-45348 species Decreases 👪 Source Study
    Bacillus sp. HBCD-sjtu species Decreases 👪 Source Study
    Bacillus sp. HC15 species Decreases 👪 Source Study
    Bacillus sp. HYC-10 species Decreases 👪 Source Study
    Bacillus sp. IHB B 7164 species Decreases 👪 Source Study
    Bacillus sp. JP44SK15 species Decreases 👪 Source Study
    Bacillus sp. LMG 18084 species Decreases 👪 Source Study
    Bacillus sp. Lzh-5 species Decreases 👪 Source Study
    Bacillus sp. N-16 species Decreases 👪 Source Study
    Bacillus sp. NCIM2463 species Decreases 👪 Source Study
    Bacillus sp. Pc3 species Decreases 👪 Source Study
    Bacillus sp. PrMC7 species Decreases 👪 Source Study
    Bacillus sp. SgZ-7 species Decreases 👪 Source Study
    Bacillus sp. SYJ species Decreases 👪 Source Study
    Bacillus sp. T41 species Decreases 👪 Source Study
    Bacillus sp. Wang species Decreases 👪 Source Study
    Bacillus sp. WP8 species Decreases 👪 Source Study
    Bacillus sp. X1(2014) species Decreases 👪 Source Study
    Bacillus sp. Y1 species Decreases 👪 Source Study
    Bacillus thermoamyloliquefaciens species Decreases 👪 Source Study
    Bacillus thuringiensis species Decreases 👪 Source Study
    Bacillus tianmuensis species Decreases 👪 Source Study
    CCM 7045 species Decreases 👪 Source Study
    CCM 7213 species Decreases 👪 Source Study
    CCM 7280 species Decreases 👪 Source Study
    CCM 7299 species Decreases 👪 Source Study
    CCM 7717 species Decreases 👪 Source Study
    CCM 7990 species Decreases 👪 Source Study
    CCTCC AB 2012022 species Decreases 👪 Source Study
    CCTCC AB 207151 species Decreases 👪 Source Study
    CCUG 51270 species Decreases 👪 Source Study
    CCUG 51504 species Decreases 👪 Source Study
    CCUG 51516 species Decreases 👪 Source Study
    CCUG 53116 species Decreases 👪 Source Study
    CCUG 58201 species Decreases 👪 Source Study
    CCUG 59304 species Decreases 👪 Source Study
    CCUG 59809 species Decreases 👪 Source Study
    CCUG 63249 species Decreases 👪 Source Study
    CECT 7670 species Decreases 👪 Source Study
    CECT 7985 species Decreases 👪 Source Study
    CECT 8338 species Decreases 👪 Source Study
    CFBP 11706 species Decreases 👪 Source Study
    CGMCC 1.15942 species Decreases 👪 Source Study
    CIP 109839 species Decreases 👪 Source Study
    CSUR P1224 species Decreases 👪 Source Study
    DSM 101070 species Decreases 👪 Source Study
    DSM 14987 species Decreases 👪 Source Study
    DSM 16611 species Decreases 👪 Source Study
    DSM 17875 species Decreases 👪 Source Study
    DSM 22905 species Decreases 👪 Source Study
    DSM 28040 species Decreases 👪 Source Study
    DSM 28043 species Decreases 👪 Source Study
    DSM 28299 species Decreases 👪 Source Study
    DSM 28300 species Decreases 👪 Source Study
    DSM 6978 species Decreases 👪 Source Study
    Enterococcus alcedinis species Decreases 👪 Source Study
    Enterococcus asini species Decreases 👪 Source Study
    Enterococcus canis species Decreases 👪 Source Study
    Enterococcus cecorum species Decreases 👪 Source Study
    Enterococcus columbae species Decreases 👪 Source Study
    enterococcus durans species Decreases 👪 Source Study
    Enterococcus gallinarum species Decreases 👪 Source Study
    Enterococcus haemoperoxidus species Decreases 👪 Source Study
    Enterococcus hermanniensis species Decreases 👪 Source Study
    Enterococcus italicus species Decreases 👪 Source Study
    Enterococcus malodoratus species Decreases 👪 Source Study
    Enterococcus sp. species Decreases 👪 Source Study
    Enterococcus sp. FDAARGOS_375 species Decreases 👪 Source Study
    Enterococcus sp. HSIEG1 species Decreases 👪 Source Study
    Enterococcus sulfureus species Decreases 👪 Source Study
    fluorescent pseudomonads species Decreases 👪 Source Study
    JCM 14963 species Decreases 👪 Source Study
    JCM 2427 species Decreases 👪 Source Study
    JCM 8722 species Decreases 👪 Source Study
    KCTC 32246 species Decreases 👪 Source Study
    KCTC 32541 species Decreases 👪 Source Study
    LTH 3734 species Decreases 👪 Source Study
    PCU:282 species Decreases 👪 Source Study
    Pseudomonas alcaligenes species Decreases 👪 Source Study
    Pseudomonas denitrificans ATCC 13867 species Decreases 👪 Source Study
    Pseudomonas gingeri species Decreases 👪 Source Study
    Pseudomonas mendocina species Decreases 👪 Source Study
    Pseudomonas oryzae species Decreases 👪 Source Study
    Pseudomonas parafulva species Decreases 👪 Source Study
    Pseudomonas putida group species Decreases 👪 Source Study
    Pseudomonas saponiphila species Decreases 👪 Source Study
    Pseudomonas sp. 02C 26 species Decreases 👪 Source Study
    Pseudomonas sp. 31-12 species Decreases 👪 Source Study
    Pseudomonas sp. 7SR1 species Decreases 👪 Source Study
    Pseudomonas sp. a101-18-2 species Decreases 👪 Source Study
    Pseudomonas sp. a111-5 species Decreases 👪 Source Study
    Pseudomonas sp. ACM7 species Decreases 👪 Source Study
    Pseudomonas sp. CC6-YY-74 species Decreases 👪 Source Study
    Pseudomonas sp. CMR12a species Decreases 👪 Source Study
    Pseudomonas sp. CMR5c species Decreases 👪 Source Study
    Pseudomonas sp. DQ-01 species Decreases 👪 Source Study
    Pseudomonas sp. DTU12.3 species Decreases 👪 Source Study
    Pseudomonas sp. DY-1 species Decreases 👪 Source Study
    Pseudomonas sp. G1116 species Decreases 👪 Source Study
    Pseudomonas sp. GmFRB023 species Decreases 👪 Source Study
    Pseudomonas sp. KB23 species Decreases 👪 Source Study
    Pseudomonas sp. KVS86 species Decreases 👪 Source Study
    Pseudomonas sp. LH1G9 species Decreases 👪 Source Study
    Pseudomonas sp. LPH1 species Decreases 👪 Source Study
    Pseudomonas sp. LTJR-52 species Decreases 👪 Source Study
    Pseudomonas sp. MFY143 species Decreases 👪 Source Study
    Pseudomonas sp. MRSN12121 species Decreases 👪 Source Study
    Pseudomonas sp. MT-1 species Decreases 👪 Source Study
    Pseudomonas sp. NS1(2017) species Decreases 👪 Source Study
    Pseudomonas sp. PcFRB072 species Decreases 👪 Source Study
    Pseudomonas sp. PcFRB119 species Decreases 👪 Source Study
    Pseudomonas sp. PONIH3 species Decreases 👪 Source Study
    Pseudomonas sp. ps4-2 species Decreases 👪 Source Study
    Pseudomonas sp. QZS01 species Decreases 👪 Source Study
    Pseudomonas sp. R4-34-07 species Decreases 👪 Source Study
    Pseudomonas sp. R5-89-07 species Decreases 👪 Source Study
    Pseudomonas sp. RU47 species Decreases 👪 Source Study
    Pseudomonas sp. S-6-2 species Decreases 👪 Source Study
    Pseudomonas sp. StFLB209 species Decreases 👪 Source Study
    Pseudomonas sp. SWI36 species Decreases 👪 Source Study
    Pseudomonas sp. TCU-HL1 species Decreases 👪 Source Study
    Pseudomonas sp. TMW 2.1634 species Decreases 👪 Source Study
    Pseudomonas sp. URMO17WK12:I11 species Decreases 👪 Source Study
    Pseudomonas sp. WCS374 species Decreases 👪 Source Study
    Pseudomonas straminea species Decreases 👪 Source Study
    Pseudomonas stutzeri group species Decreases 👪 Source Study
    Pseudomonas syringae group species Decreases 👪 Source Study
    Salmonella sp. 111 species Decreases 👪 Source Study
    Staphylococcus auricularis species Decreases 👪 Source Study
    Staphylococcus capitis species Decreases 👪 Source Study
    Staphylococcus chromogenes species Decreases 👪 Source Study
    Staphylococcus devriesei species Decreases 👪 Source Study
    Staphylococcus haemolyticus species Decreases 👪 Source Study
    Staphylococcus pasteuri species Decreases 👪 Source Study
    Staphylococcus piscifermentans species Decreases 👪 Source Study
    Staphylococcus sp. 3035O2 species Decreases 👪 Source Study
    Staphylococcus sp. 3356O2 species Decreases 👪 Source Study
    Staphylococcus sp. FXY54 species Decreases 👪 Source Study
    Staphylococcus sp. L10 species Decreases 👪 Source Study
    Staphylococcus sp. M0911 species Decreases 👪 Source Study
    Staphylococcus sp. SDB 2975 species Decreases 👪 Source Study
    Staphylococcus sp. WB17-17 species Decreases 👪 Source Study
    Staphylococcus sp. WB18-16 species Decreases 👪 Source Study
    Staphylococcus vitulinus species Decreases 👪 Source Study
    Staphylococcus xylosus species Decreases 👪 Source Study
    strain Alg07 species Decreases 👪 Source Study
    Yersinia ruckeri species Decreases 👪 Source Study

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