We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Age: 20-30 | Worsen | 2.48 |
Age: 60-70 | Improves | -2.92 |
Autonomic Manifestations: Orthostatic intolerance | Improves | -2.92 |
Autonomic: Inability to tolerate an upright position | Improves | -2.92 |
Autonomic: Irregular heartbeats | Improves | -2.92 |
Blood Type: A Positive | Improves | -1.86 |
Blood Type: O Positive | Improves | -3.17 |
Comorbid-Mouth: Dry Mouth | Worsen | 2.74 |
Comorbid: Constipation and Explosions (not diarrohea) | Improves | -2.92 |
Comorbid: High Anxiety | Improves | -2.92 |
Comorbid: Inflammatory bowel disease | Improves | -3.17 |
Comorbid: Migraine | Improves | -1.86 |
Comorbid: Multiple Chemical Sensitivity | Worsen | 2.68 |
Comorbid: Snoring (NOT Sleep Apnea | Improves | -2.92 |
DePaul University Fatigue Questionnaire : Allergies | Worsen | 0 |
DePaul University Fatigue Questionnaire : Anxiety/tension | Worsen | 0 |
DePaul University Fatigue Questionnaire : Fatigue | Improves | -3.17 |
DePaul University Fatigue Questionnaire : Forgetting what you are trying to say | Worsen | 0 |
DePaul University Fatigue Questionnaire : Impaired Memory & concentration | Improves | -2.92 |
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired | Improves | -1.86 |
DePaul University Fatigue Questionnaire : Walking up early in the morning (e.g. 3AM) | Worsen | 0 |
General: Headaches | Worsen | 1.62 |
Joint: Stiffness and swelling | Improves | -2.64 |
Joint: Tenderness | Improves | -2.92 |
Neuroendocrine Manifestations: Excessive adrenaline | Worsen | 1.68 |
Neuroendocrine: Alcohol intolerance | Worsen | 1.7 |
Neuroendocrine: Feeling like you have a low temperature | Worsen | 2.74 |
Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep) | Improves | -2.92 |
Neurological-Sleep: Insomnia | Improves | -2.92 |
Neurological-Vision: inability to focus eye/vision | Improves | -2.92 |
Neurological: emotional overload | Worsen | 2.74 |
Neurological: fasciculations | Worsen | 2.74 |
Neurological: High degree of Empathy before onset | Worsen | 2.74 |
Neurological: Joint hypermobility | Improves | -2.92 |
Neurological: Short-term memory issues | Worsen | 2.74 |
Neurological: Slowed speech | Worsen | 1.61 |
Neurological: Spatial instability and disorientation | Worsen | 2.74 |
Official Diagnosis: Autoimmune Disease | Improves | -2.92 |
Official Diagnosis: Irritable Bowel Syndrome | Improves | -2.92 |
Official Diagnosis: Mast Cell Dysfunction | Improves | -2.64 |
Post-exertional malaise: General | Worsen | 2.74 |
Post-exertional malaise: Mentally tired after the slightest effort | Worsen | 3.5 |
Post-exertional malaise: Physically drained or sick after mild activity | Worsen | 2.74 |
Post-exertional malaise: Post-exertional malaise | Worsen | 2.74 |
Post-exertional malaise: Rapid cognitive fatigability, | Worsen | 3.55 |
Post-exertional malaise: Worsening of symptoms after mild mental activity | Worsen | 2.74 |
Sleep: Problems staying asleep | Worsen | 1.7 |
Sleep: Waking up early in the morning (e.g. 3 AM) | Improves | -2.92 |
We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is according to the microbiome shifts reported in studies. Clinical studies may show different results
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Acne | Improves | -3.76 |
ADHD | Worsen | 3.38 |
Allergies | Worsen | 2.13 |
Alzheimer's disease | Improves | -4.26 |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | Worsen | 3.49 |
Ankylosing spondylitis | Worsen | 4.69 |
Asthma | Worsen | 2.64 |
Atherosclerosis | Improves | -4 |
Autism | Improves | -4.92 |
Barrett esophagus cancer | Improves | -3.36 |
Brain Trauma | Improves | -2.76 |
Carcinoma | Improves | -2.41 |
Celiac Disease | Improves | -4.08 |
Chronic Fatigue Syndrome | Improves | -4.52 |
Chronic Kidney Disease | Improves | -3.25 |
Chronic urticaria (Hives) | Improves | -3.7 |
Colorectal Cancer | Improves | -4.36 |
Coronary artery disease | Worsen | 2.32 |
Crohn's Disease | Improves | -5.33 |
cystic fibrosis | Improves | -3.57 |
Depression | Improves | -0.32 |
Epilepsy | Improves | -4.31 |
Fibromyalgia | Improves | -3.72 |
gallstone disease (gsd) | Improves | -3.73 |
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | Improves | -4 |
Generalized anxiety disorder | Improves | -4.54 |
Graves' disease | Worsen | 2.74 |
Hashimoto's thyroiditis | Improves | -2.93 |
High Blood Pressure | Improves | -3.43 |
Histamine Issues | Improves | -3.75 |
Histamine Issues From Ubiome | Improves | -0.77 |
Hyperlipidemia (High Blood Fats) | Improves | -2.05 |
hypertension (High Blood Pressure | Improves | -3.09 |
IgA nephropathy (IgAN) | Improves | -3.56 |
Inflammatory Bowel Disease | Improves | -4.99 |
Irritable Bowel Syndrome | Improves | -5.1 |
Liver Cirrhosis | Improves | -4.41 |
ME/CFS with IBS | Improves | -2.93 |
ME/CFS without IBS | Improves | -3.51 |
Metabolic Syndrome | Improves | -3.01 |
Mood Disorders | Improves | -2.74 |
Multiple Sclerosis | Improves | -3.51 |
Multiple system atrophy (MSA) | Worsen | 1.75 |
neuropsychiatric disorders (PANDAS, PANS) | Improves | -2.42 |
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | Improves | -3.1 |
Obesity | Improves | -4.64 |
Osteoporosis | Improves | -1.78 |
Parkinson's Disease | Worsen | 4.33 |
Psoriasis | Improves | -2.65 |
Rheumatoid arthritis | Improves | -4.11 |
rheumatoid arthritis (RA),Spondyloarthritis (SpA) | Improves | -2.46 |
Rosacea | Worsen | 2.74 |
Schizophrenia | Worsen | 3.77 |
Sclerosis | Improves | -2.56 |
Sjögren syndrome | Improves | -2.26 |
Small Intestinal Bacterial Overgrowth (SIBO) | Improves | -3.96 |
Stress / posttraumatic stress disorder | Improves | -4.93 |
Systemic Lupus Erythematosus | Worsen | 3.71 |
Type 1 Diabetes | Worsen | 3.26 |
Type 2 Diabetes | Worsen | 3.17 |
Ulcerative colitis | Improves | -4.11 |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.