spectinomycin (antibiotic)s ** full range

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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

Symptom	Impact	Predictor of Bacteria Shift
Age: 0-10	Worsen	2.88
Neuroendocrine: Feeling like you have a low temperature	Improves	-2.74
Neurological: emotional overload	Improves	-2.74
Neurological: fasciculations	Improves	-2.74
Neurological: High degree of Empathy before onset	Improves	-2.74
Neurological: Short-term memory issues	Improves	-2.74
Neurological: Spatial instability and disorientation	Improves	-2.74
Onset: less than 02 years since onset	Improves	-2.74
Post-exertional malaise: Mentally tired after the slightest effort	Improves	-2.88
Post-exertional malaise: Worsening of symptoms after mild mental activity	Improves	-2.74

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

Symptom	Impact	Predictor of Bacteria Shift
Acne	Worsen	3.94
ADHD	Improves	-3.99
Allergic Rhinitis (Hay Fever)	Worsen	2.88
Allergies	Improves	-2.57
Alzheimer's disease	Worsen	1.95
Amyotrophic lateral sclerosis (ALS) Motor Neuron	Improves	-3.07
Ankylosing spondylitis	Improves	-4.25
Asthma	Improves	-2.88
Atherosclerosis	Improves	-4.05
Autism	Worsen	4.43
Barrett esophagus cancer	Improves	-1.46
Bipolar Disorder	Improves	-2.43
Brain Trauma	Worsen	3.39
Carcinoma	Worsen	0
Celiac Disease	Worsen	3.94
Cerebral Palsy	Improves	-1.82
Chronic Fatigue Syndrome	Worsen	4.77
Chronic Kidney Disease	Worsen	2.72
Chronic Lyme	Worsen	2.74
Colorectal Cancer	Improves	-1.44
COVID-19	Worsen	3.25
Crohn's Disease	Worsen	3.77
cystic fibrosis	Worsen	2.43
Depression	Worsen	3.79
Epilepsy	Worsen	3.78
Fibromyalgia	Worsen	3.89
Functional constipation / chronic idiopathic constipation	Improves	-2.88
gallstone disease (gsd)	Worsen	2.88
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus	Worsen	1.46
Generalized anxiety disorder	Worsen	2.71
Graves' disease	Improves	-2.74
Hashimoto's thyroiditis	Worsen	2.88
High Blood Pressure	Worsen	1.25
Histamine Issues	Worsen	3.03
Histamine Issues From Ubiome	Worsen	2.72
hypercholesterolemia (High Cholesterol)	Worsen	2.39
Hyperlipidemia (High Blood Fats)	Improves	-1.3
IgA nephropathy (IgAN)	Worsen	3.55
Inflammatory Bowel Disease	Worsen	3.33
Irritable Bowel Syndrome	Worsen	4.69
Liver Cirrhosis	Worsen	3.86
ME/CFS with IBS	Worsen	2.88
ME/CFS without IBS	Worsen	3.65
Mood Disorders	Worsen	2.74
Multiple Sclerosis	Improves	-2.37
Multiple system atrophy (MSA)	Worsen	1.3
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic	Worsen	4.47
NonCeliac Gluten Sensitivity	Worsen	2.88
Obesity	Worsen	2.78
Osteoporosis	Improves	-2.72
Parkinson's Disease	Improves	-4.08
Psoriasis	Improves	-3.62
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	Worsen	4.27
Rosacea	Improves	-2.65
Schizophrenia	Improves	-4.65
Sjögren syndrome	Worsen	3.75
Small Intestinal Bacterial Overgrowth (SIBO)	Worsen	2.54
Stress / posttraumatic stress disorder	Worsen	4.14
Systemic Lupus Erythematosus	Worsen	4.25
Type 1 Diabetes	Worsen	3.78
Type 2 Diabetes	Worsen	1.77
Ulcerative colitis	Worsen	3.45

Bacteria Impacted

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.