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sulfonamide antibiotics ** full range

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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomImpactPredictor of Bacteria Shift
Age: 20-30Worsen6.53
Age: 30-40Improves-4.29
Age: 40-50Improves-3.55
Age: 50-60Improves-5.25
Age: 60-70Improves-7.19
Asymptomatic: Live in house with person with probable microbiome dysfunctionImproves-2.39
Asymptomatic: Minor Health Issues (a few symptoms only)Improves-6.36
Asymptomatic: No Health IssuesImproves-6.13
Autism: Official DiagnosisImproves-8.61
Autonomic Manifestations: cardiac arrhythmiasWorsen8.72
Autonomic Manifestations: Cortisol disorders or irregularity Improves-3.48
Autonomic Manifestations: irritable bowel syndromeWorsen5.68
Autonomic Manifestations: light-headednessImproves-2.56
Autonomic Manifestations: Orthostatic intoleranceWorsen7.65
Autonomic Manifestations: palpitationsWorsen8.4
Autonomic Manifestations: urinary frequency dysfunctionWorsen8.38
Autonomic: Dizziness or faintingImproves-2.77
Autonomic: Heart rate increase after standingWorsen6.58
Autonomic: Inability to tolerate an upright positionImproves-8.14
Autonomic: Irregular heartbeatsImproves-8.25
Autonomic: Ocassional Tachycardia (Rapid heart beat)Worsen6.87
Autonomic: Shortness of breathWorsen5.79
Blood Type: A PositiveWorsen6.39
Blood Type: O PositiveImproves-9.13
Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grindingImproves-7.5
Comorbid-Mouth: Dry MouthWorsen7.68
Comorbid-Mouth: Mouth SoresImproves-7.89
Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndromeImproves-8.12
Comorbid: Constipation and Explosions (not diarrohea)Improves-9.06
Comorbid: FibromyalgiaWorsen7.31
Comorbid: High AnxietyImproves-8.95
Comorbid: Histamine or Mast Cell issuesImproves-8
Comorbid: HypothyroidismImproves-7.85
Comorbid: Inflammatory bowel disease Improves-8.83
Comorbid: MigraineImproves-8.88
Comorbid: Mold Sensitivity / ExposureWorsen6.87
Comorbid: Multiple Chemical SensitivityWorsen6.27
Comorbid: Restless LegImproves-6.91
Comorbid: Snoring (NOT Sleep ApneaImproves-8.53
DePaul University Fatigue Questionnaire : FatigueImproves-9.18
DePaul University Fatigue Questionnaire : Impaired Memory & concentrationImproves-9.4
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired Improves-9.1
Gender: FemaleImproves-6.78
Gender: MaleImproves-3.82
General: DepressionImproves-7.17
General: FatigueWorsen8.12
General: HeadachesWorsen6.12
General: Heavy feeling in arms and legsWorsen4.77
General: Myalgia (pain)Worsen6.34
General: Sinus issues with headachesImproves-6.45
Immune Manifestations: Abdominal PainImproves-7.7
Immune Manifestations: Alcohol IntolerantImproves-5.42
Immune Manifestations: BloatingImproves-5.81
Immune Manifestations: ConstipationWorsen7.41
Immune Manifestations: DiarrheaWorsen7.01
Immune Manifestations: general malaiseWorsen7.85
Immune Manifestations: Hair lossImproves-3.73
Immune Manifestations: Inflammation (General)Improves-8.81
Immune Manifestations: Inflammation of skin, eyes or jointsImproves-5
Immune Manifestations: medication sensitivities.Improves-3.88
Immune Manifestations: Mucus in the stoolImproves-9.07
Immune Manifestations: new food sensitivitiesWorsen7.67
Immune Manifestations: tender lymph nodesWorsen7.81
Immune: Chronic SinusitisWorsen5.21
Immune: Sensitivity to smell/food/medication/chemicalsWorsen5.24
Infection: Epstein-Barr virusImproves-7.59
Infection: Human Herpesvirus 6 (HHV6)Improves-8.04
Infection: LymeImproves-7.81
Infection: MycoplasmaImproves-8.35
Infection: Parasite - OtherImproves-7.63
Joint: RednessImproves-4.55
Joint: Stiffness and swellingImproves-7.24
Joint: Sudden and severe episodes of painWorsen6.28
Joint: TendernessImproves-8.5
Neurocognitive: Absent-mindedness or forgetfulnessWorsen5.35
Neurocognitive: Brain FogWorsen6.09
Neurocognitive: Can only focus on one thing at a timeImproves-6.35
Neurocognitive: Difficulty expressing thoughtsWorsen5.26
Neurocognitive: Difficulty paying attention for a long period of timeImproves-6.01
Neurocognitive: Difficulty understanding thingsWorsen3.35
Neurocognitive: Problems remembering thingsImproves-5.99
Neurocognitive: Slowness of thoughtImproves-6.49
Neurocognitive: Unable to focus vision and/or attentionImproves-6.92
Neuroendocrine Manifestations: Air HungerWorsen6.87
Neuroendocrine Manifestations: cold extremitiesWorsen7.36
Neuroendocrine Manifestations: Dry Eye (Sicca or Sjogren Syndrome)Improves-4.29
Neuroendocrine Manifestations: Excessive adrenalineImproves-7.52
Neuroendocrine Manifestations: intolerance of extremes of heat and coldWorsen7.19
Neuroendocrine Manifestations: marked weight change Improves-0.34
Neuroendocrine Manifestations: Muscle weakness Worsen7.52
Neuroendocrine Manifestations: NeuralgiaImproves-3.52
Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin)Improves-8.51
Neuroendocrine Manifestations: Rapid muscular fatiguabilityWorsen4.43
Neuroendocrine Manifestations: recurrent feelings of feverishnessImproves-3.88
Neuroendocrine Manifestations: subnormal body temperatureWorsen6.61
Neuroendocrine Manifestations: sweating episodesWorsen6.67
Neuroendocrine Manifestations: worsening of symptoms with stress.Worsen7.39
Neuroendocrine: Alcohol intoleranceImproves-5.68
Neuroendocrine: Chills or shiversImproves-4.1
Neuroendocrine: Cold limbs (e.g. arms, legs hands)Improves-4.06
Neuroendocrine: Feeling hot or cold for no reasonWorsen7.95
Neuroendocrine: Feeling like you have a high temperatureWorsen4.23
Neuroendocrine: Feeling like you have a low temperatureWorsen7.5
Neuroendocrine: Lack of appetiteWorsen6.84
Neuroendocrine: Lost or gained weight without tryingWorsen7.57
Neuroendocrine: Sweating handsWorsen2.75
Neurological-Audio: hypersensitivity to noiseWorsen7.36
Neurological-Audio: Tinnitus (ringing in ear)Improves-6.21
Neurological-Sleep: Chaotic diurnal sleep rhythms (Irratic Sleep)Worsen6.96
Neurological-Sleep: InsomniaWorsen4.92
Neurological-Sleep: Night SweatsWorsen3.25
Neurological-Sleep: Sleep ApneaWorsen5.82
Neurological-Sleep: Vivid Dreams/NightmaresWorsen7.64
Neurological-Vision: Blurred VisionWorsen7.56
Neurological-Vision: inability to focus eye/visionImproves-6.29
Neurological-Vision: photophobia (Light Sensitibity)Improves-7.55
Neurological: Cognitive OverloadWorsen6.96
Neurological: Difficulty processing information (Understanding)Worsen7.5
Neurological: Difficulty readingImproves-7.21
Neurological: DysautonomiaWorsen0
Neurological: emotional overloadWorsen7.77
Neurological: Executive Decision Making (Difficulty making)Improves-7.39
Neurological: fasciculations Worsen7.89
Neurological: High degree of Empathy before onsetWorsen7.49
Neurological: Impairment of concentrationWorsen6.07
Neurological: Joint hypermobilityImproves-8.2
Neurological: Seasonal Affective Disorder (SAD)Improves-7.98
Neurological: Short-term memory issuesWorsen7.76
Neurological: Slowed speechImproves-1.82
Neurological: Spatial instability and disorientationWorsen7.5
Neurological: Word-finding problemsWorsen4.46
Official Diagnosis: Allergic Rhinitis (Hay Fever)Improves-8.8
Official Diagnosis: Autoimmune DiseaseImproves-8.03
Official Diagnosis: Chronic Fatigue SyndromeWorsen4.58
Official Diagnosis: Irritable Bowel SyndromeImproves-8.1
Official Diagnosis: Mast Cell DysfunctionImproves-7.52
Onset: 2000-2010Worsen5.03
Onset: 2010-2020Worsen6.22
Onset: GradualWorsen5.66
Onset: less than 16 years since onsetWorsen0
Other: Sensitivity to moldWorsen6.93
Pain: Chest painImproves-7.16
Pain: Eye painImproves-6.55
Pain: Joint painImproves-3.09
Pain: Myofascial painImproves-4.87
Pain: Pain or aching in musclesWorsen7.82
Pain: Sensitivity to painImproves-8.59
Post-exertional malaise: Difficulty reading after mild physical or mental activityWorsen4.31
Post-exertional malaise: GeneralWorsen7.48
Post-exertional malaise: Inappropriate loss of physical and mental stamina,Improves-2.95
Post-exertional malaise: Mentally tired after the slightest effortImproves-6.4
Post-exertional malaise: Next-day soreness after everyday activitiesWorsen3.42
Post-exertional malaise: Physically drained or sick after mild activityWorsen6.72
Post-exertional malaise: Physically tired after minimum exerciseImproves-6.78
Post-exertional malaise: Rapid cognitive fatigability, Worsen8.16
Post-exertional malaise: Rapid muscular fatigability, Worsen6.43
Post-exertional malaise: Worsening of symptoms after mild mental activityWorsen7.49
Post-exertional malaise: Worsening of symptoms after mild physical activityWorsen6.6
Sleep: Daytime drowsinessWorsen7.63
Sleep: Need to nap dailyImproves-6.36
Sleep: Problems falling asleepWorsen6.87
Sleep: Problems staying asleepWorsen5.91
Sleep: Unrefreshed sleepWorsen8.04
Sleep: Waking up early in the morning (e.g. 3 AM)Improves-7.19

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomImpactPredictor of Bacteria Shift
AcneWorsen5.97
ADHDImproves-8.22
Allergic Rhinitis (Hay Fever)Improves-3.24
AllergiesWorsen7.73
Alzheimer's diseaseWorsen8.83
Amyotrophic lateral sclerosis (ALS) Motor NeuronWorsen7.76
Ankylosing spondylitisWorsen9.22
AsthmaWorsen5.67
AtherosclerosisImproves-9.6
AutismWorsen9.73
Autoimmune DiseaseImproves-3.29
Barrett esophagus cancerImproves-6.03
Brain TraumaImproves-6.89
CarcinomaImproves-9.03
Celiac DiseaseImproves-5.4
Chronic Fatigue SyndromeImproves-7.4
Chronic Kidney DiseaseImproves-7.56
Chronic urticaria (Hives)Improves-8.55
Colorectal CancerImproves-10.61
Crohn's DiseaseImproves-9.75
cystic fibrosisImproves-7.49
DepressionImproves-9.13
EpilepsyWorsen8.25
FibromyalgiaWorsen7.49
Functional constipation / chronic idiopathic constipationImproves-8.21
Gastro-esophageal reflux disease (Gerd) including Barrett's esophagusWorsen7.3
Generalized anxiety disorderImproves-8.69
GoutImproves-6.12
Graves' diseaseWorsen6.97
Hashimoto's thyroiditisImproves-7.8
High Blood PressureWorsen8.63
Histamine IssuesImproves-8.9
Histamine Issues From UbiomeWorsen6.01
hypercholesterolemia (High Cholesterol)Improves-7.01
IgA nephropathy (IgAN)Worsen8.52
Inflammatory Bowel DiseaseImproves-9.07
Irritable Bowel SyndromeImproves-9.4
Juvenile idiopathic arthritisWorsen5.45
Liver CirrhosisImproves-9.14
ME/CFS with IBSImproves-8.5
ME/CFS without IBSImproves-9.27
Metabolic SyndromeWorsen7.16
Mood DisordersImproves-7.57
Multiple SclerosisImproves-8.86
neuropsychiatric disorders (PANDAS, PANS)Improves-8.02
Non-alcoholic Fatty Liver Disease (nafld) NonalcoholicImproves-6.8
Non-Celiac Gluten SensitivityWorsen1.35
ObesityImproves-9.07
Parkinson's DiseaseImproves-8.14
PsoriasisImproves-9.34
Rheumatoid arthritisWorsen8.15
rheumatoid arthritis (RA) and Spondyloarthritis (SpA)Improves-8.43
SchizophreniaWorsen7.86
SclerosisWorsen6.54
Sjögren syndromeImproves-8.4
Small Intestinal Bacterial Overgrowth (SIBO)Improves-9.08
Stress / post-traumatic stress disorderImproves-9.85
Systemic Lupus ErythematosusImproves-8.95
Type 1 DiabetesImproves-7.25
Type 2 DiabetesImproves-8.21
Ulcerative colitisWorsen8.38

Bacteria Impacted

Suggest a missed study:

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Gammaproteobacteria class Increases 📓 Source Study
Enterobacteriaceae family Increases 📓 Source Study
Mycobacteriaceae family Increases 📓 Source Study
Pasteurellaceae family Increases 📓 Source Study
Pseudomonadaceae family Increases 📓 Source Study
Actinobacillus genus Increases 👪 Source Study
Aggregatibacter genus Increases 👪 Source Study
Atlantibacter genus Increases 👪 Source Study
Avibacterium genus Increases 👪 Source Study
Basfia genus Increases 👪 Source Study
Bibersteinia genus Increases 👪 Source Study
Biostraticola genus Increases 👪 Source Study
Bisgaardia genus Increases 👪 Source Study
Buttiauxella genus Increases 👪 Source Study
Candidatus Ishikawaella genus Increases 👪 Source Study
Cedecea genus Increases 👪 Source Study
Gallibacterium genus Increases 👪 Source Study
Gibbsiella genus Increases 👪 Source Study
Glaesserella genus Increases 👪 Source Study
Histophilus genus Increases 👪 Source Study
Hoyosella genus Increases 👪 Source Study
Kosakonia genus Increases 👪 Source Study
Leclercia genus Increases 👪 Source Study
Lelliottia genus Increases 👪 Source Study
Limnobaculum genus Increases 👪 Source Study
MAC genus Increases 👪 Source Study
Mannheimia genus Increases 👪 Source Study
Metakosakonia genus Increases 👪 Source Study
Moranella genus Increases 👪 Source Study
Mycobacterium chelonae complex genus Increases 👪 Source Study
Mycobacterium complex genus Increases 👪 Source Study
Mycobacterium fortuitum complex genus Increases 👪 Source Study
Mycobacterium terrae complex genus Increases 👪 Source Study
Necropsobacter genus Increases 👪 Source Study
Nicoletella genus Increases 👪 Source Study
Oblitimonas genus Increases 👪 Source Study
Otariodibacter genus Increases 👪 Source Study
Pasteurella genus Increases 👪 Source Study
Permianibacter genus Increases 👪 Source Study
Pluralibacter genus Increases 👪 Source Study
Pseudescherichia genus Increases 👪 Source Study
Pseudomonas chlororaphis group genus Increases 👪 Source Study
Raoultella genus Increases 👪 Source Study
Riesia genus Increases 👪 Source Study
Rodentibacter genus Increases 👪 Source Study
Rosenbergiella genus Increases 👪 Source Study
Rugamonas genus Increases 👪 Source Study
Shimwellia genus Increases 👪 Source Study
Siccibacter genus Increases 👪 Source Study
Ursidibacter genus Increases 👪 Source Study
Volucribacter genus Increases 👪 Source Study
Yokenella genus Increases 👪 Source Study
Actinobacillus genus Increases 📓 Source Study
Levinea Young et al. 1971 genus Increases 📓 Source Study
Mycobacterium genus Increases 📓 Source Study
Pseudomonas genus Increases 📓 Source Study
Achromobacter georgiopolitanum species Increases 👪 Source Study
Actinobacillus arthritidis species Increases 👪 Source Study
Actinobacillus delphinicola species Increases 👪 Source Study
Actinobacillus pleuropneumoniae species Increases 👪 Source Study
Actinobacillus porcinus species Increases 👪 Source Study
Actinobacillus porcitonsillarum species Increases 👪 Source Study
Actinobacillus scotiae species Increases 👪 Source Study
Actinobacillus succinogenes species Increases 👪 Source Study
Actinobacillus suis species Increases 👪 Source Study
AJ 2129 species Increases 👪 Source Study
Arthrobacter sp. BDR2P1B1-M species Increases 👪 Source Study
ATCC 12478 species Increases 👪 Source Study
ATCC 29548 species Increases 👪 Source Study
ATCC 51112 species Increases 👪 Source Study
ATCC BAA-257 species Increases 👪 Source Study
CCM 7280 species Increases 👪 Source Study
CCM 7990 species Increases 👪 Source Study
CCTCC AB 2012022 species Increases 👪 Source Study
CCTCC AB 207151 species Increases 👪 Source Study
CCUG 51504 species Increases 👪 Source Study
CCUG 51516 species Increases 👪 Source Study
CCUG 53116 species Increases 👪 Source Study
CCUG 58201 species Increases 👪 Source Study
CCUG 63249 species Increases 👪 Source Study
CECT 7670 species Increases 👪 Source Study
CECT 7985 species Increases 👪 Source Study
CECT 8338 species Increases 👪 Source Study
CFBP 11706 species Increases 👪 Source Study
CIP 109839 species Increases 👪 Source Study
Citrobacter amalonaticus species Increases 👪 Source Study
Citrobacter sp. species Increases 👪 Source Study
Citrobacter sp. BW4 species Increases 👪 Source Study
Citrobacter sp. HD4.9 species Increases 👪 Source Study
CSUR P1224 species Increases 👪 Source Study
DSM 101070 species Increases 👪 Source Study
DSM 16611 species Increases 👪 Source Study
DSM 17875 species Increases 👪 Source Study
DSM 28040 species Increases 👪 Source Study
DSM 28043 species Increases 👪 Source Study
DSM 5568 species Increases 👪 Source Study
DSM 6978 species Increases 👪 Source Study
fluorescent pseudomonads species Increases 👪 Source Study
JCM 14963 species Increases 👪 Source Study
JCM 1658 species Increases 👪 Source Study
JCM 18565 species Increases 👪 Source Study
KCTC 32246 species Increases 👪 Source Study
KCTC 32541 species Increases 👪 Source Study
Mycobacterium simiae complex species Increases 👪 Source Study
Mycobacterium sp. BJC15-C31 species Increases 👪 Source Study
Mycobacterium sp. CRRI 4 species Increases 👪 Source Study
Mycobacterium sp. djl-10 species Increases 👪 Source Study
Mycobacterium sp. DL90 species Increases 👪 Source Study
Mycobacterium sp. EPa45 species Increases 👪 Source Study
Mycobacterium sp. FI 1033 species Increases 👪 Source Study
Mycobacterium sp. JS623 species Increases 👪 Source Study
Mycobacterium sp. KNUC287 species Increases 👪 Source Study
Mycobacterium sp. KNUC297 species Increases 👪 Source Study
Mycobacterium sp. MS1601 species Increases 👪 Source Study
Mycobacterium sp. UNC410CL29Cvi84 species Increases 👪 Source Study
Prevotella sp. 109 species Increases 👪 Source Study
Pseudomonas denitrificans ATCC 13867 species Increases 👪 Source Study
Pseudomonas gingeri species Increases 👪 Source Study
Pseudomonas oryzae species Increases 👪 Source Study
Pseudomonas putida group species Increases 👪 Source Study
Pseudomonas saponiphila species Increases 👪 Source Study
Pseudomonas sp. 02C 26 species Increases 👪 Source Study
Pseudomonas sp. 31-12 species Increases 👪 Source Study
Pseudomonas sp. 7SR1 species Increases 👪 Source Study
Pseudomonas sp. a101-18-2 species Increases 👪 Source Study
Pseudomonas sp. a111-5 species Increases 👪 Source Study
Pseudomonas sp. ACM7 species Increases 👪 Source Study
Pseudomonas sp. CC6-YY-74 species Increases 👪 Source Study
Pseudomonas sp. CMR12a species Increases 👪 Source Study
Pseudomonas sp. CMR5c species Increases 👪 Source Study
Pseudomonas sp. DQ-01 species Increases 👪 Source Study
Pseudomonas sp. DTU12.3 species Increases 👪 Source Study
Pseudomonas sp. DY-1 species Increases 👪 Source Study
Pseudomonas sp. G1116 species Increases 👪 Source Study
Pseudomonas sp. GmFRB023 species Increases 👪 Source Study
Pseudomonas sp. KB23 species Increases 👪 Source Study
Pseudomonas sp. KVS86 species Increases 👪 Source Study
Pseudomonas sp. LH1G9 species Increases 👪 Source Study
Pseudomonas sp. LPH1 species Increases 👪 Source Study
Pseudomonas sp. LTJR-52 species Increases 👪 Source Study
Pseudomonas sp. MFY143 species Increases 👪 Source Study
Pseudomonas sp. MRSN12121 species Increases 👪 Source Study
Pseudomonas sp. MT-1 species Increases 👪 Source Study
Pseudomonas sp. NS1(2017) species Increases 👪 Source Study
Pseudomonas sp. PcFRB072 species Increases 👪 Source Study
Pseudomonas sp. PcFRB119 species Increases 👪 Source Study
Pseudomonas sp. PONIH3 species Increases 👪 Source Study
Pseudomonas sp. ps4-2 species Increases 👪 Source Study
Pseudomonas sp. QZS01 species Increases 👪 Source Study
Pseudomonas sp. R4-34-07 species Increases 👪 Source Study
Pseudomonas sp. R5-89-07 species Increases 👪 Source Study
Pseudomonas sp. RU47 species Increases 👪 Source Study
Pseudomonas sp. S-6-2 species Increases 👪 Source Study
Pseudomonas sp. StFLB209 species Increases 👪 Source Study
Pseudomonas sp. SWI36 species Increases 👪 Source Study
Pseudomonas sp. TCU-HL1 species Increases 👪 Source Study
Pseudomonas sp. TMW 2.1634 species Increases 👪 Source Study
Pseudomonas sp. URMO17WK12:I11 species Increases 👪 Source Study
Pseudomonas sp. WCS374 species Increases 👪 Source Study
Pseudomonas stutzeri group species Increases 👪 Source Study
Pseudomonas syringae group species Increases 👪 Source Study
strain PH-06 species Increases 👪 Source Study

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