beta lactam (antibiotic)s ** full range

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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

Symptom	Impact	Predictor of Bacteria Shift
Comorbid: Fibromyalgia	Improves	-2.96
DePaul University Fatigue Questionnaire : Difficulty falling asleep	Improves	-2.96
DePaul University Fatigue Questionnaire : Difficulty finding the right word	Improves	-1.71
Neuroendocrine: Feeling like you have a low temperature	Improves	-2.74
Neurological: emotional overload	Improves	-2.74
Neurological: Executive Decision Making (Difficulty making)	Worsen	2.42
Neurological: fasciculations	Improves	-2.74
Neurological: High degree of Empathy before onset	Improves	-2.74
Neurological: Impairment of concentration	Worsen	2.42
Neurological: Short-term memory issues	Improves	-2.74
Neurological: Spatial instability and disorientation	Improves	-2.74
Onset: less than 02 years since onset	Improves	-2.74
Pain: Sensitivity to pain	Improves	-1.71
Post-exertional malaise: Worsening of symptoms after mild mental activity	Improves	-2.74

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

Symptom	Impact	Predictor of Bacteria Shift
Acne	Improves	-2.42
Allergic Rhinitis (Hay Fever)	Improves	-2.41
Allergies	Improves	-2.86
Amyotrophic lateral sclerosis (ALS) Motor Neuron	Improves	-2.41
Ankylosing spondylitis	Worsen	2.63
Asthma	Worsen	2.21
Atherosclerosis	Improves	-2.82
Autism	Worsen	2.91
Bipolar Disorder	Improves	-2.93
Brain Trauma	Worsen	3.28
Carcinoma	Improves	-3.63
Celiac Disease	Improves	-3.1
Chronic Fatigue Syndrome	Worsen	2.45
Chronic Kidney Disease	Improves	-2.41
Chronic Lyme	Worsen	2.74
Chronic Urticaria (Hives)	Improves	-3.06
Colorectal Cancer	Improves	-3.46
COVID-19	Improves	-0.54
Crohn's Disease	Improves	-3.51
cystic fibrosis	Improves	-3.94
Depression	Worsen	3.93
Eczema	Worsen	3.88
Fibromyalgia	Worsen	3.17
Functional constipation / chronic idiopathic constipation	Improves	-2.63
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus	Improves	-2.69
Generalized anxiety disorder	Improves	-3.45
Graves' disease	Improves	-3.52
Hashimoto's thyroiditis	Improves	-2.42
High Blood Pressure	Worsen	1.59
Histamine Issues	Improves	-3.75
hypercholesterolemia (High Cholesterol)	Worsen	2.69
IgA nephropathy (IgAN)	Worsen	2.74
Inflammatory Bowel Disease	Improves	-4.7
Irritable Bowel Syndrome	Worsen	2.65
Liver Cirrhosis	Improves	-4.36
ME/CFS without IBS	Worsen	1.82
Mood Disorders	Worsen	2.74
Multiple Sclerosis	Improves	-3.74
neuropsychiatric disorders (PANDAS, PANS)	Improves	-2.42
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic	Worsen	3.5
Obesity	Improves	-3.09
Osteoarthritis	Improves	-2.41
Osteoporosis	Improves	-2.41
Parkinson's Disease	Worsen	3.92
Psoriasis	Improves	-2.97
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	Improves	-4.28
Rosacea	Worsen	2.69
Schizophrenia	Improves	-0.07
Sjögren syndrome	Improves	-2.41
Small Intestinal Bacterial Overgrowth (SIBO)	Improves	-4.26
Stress / posttraumatic stress disorder	Improves	-3.58
Systemic Lupus Erythematosus	Improves	-2.24
Type 1 Diabetes	Worsen	3.69
Type 2 Diabetes	Improves	-3.23
Ulcerative colitis	Improves	-4.02

Bacteria Impacted

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.