We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Age: 20-30 | Worsen | 2.48 |
Comorbid-Mouth: Dry Mouth | Worsen | 2.74 |
Neuroendocrine: Feeling like you have a low temperature | Worsen | 2.74 |
Neurological: emotional overload | Worsen | 2.74 |
Neurological: Executive Decision Making (Difficulty making) | Worsen | 2.42 |
Neurological: fasciculations | Worsen | 2.74 |
Neurological: High degree of Empathy before onset | Worsen | 2.74 |
Neurological: Short-term memory issues | Worsen | 2.74 |
Neurological: Spatial instability and disorientation | Worsen | 2.74 |
Post-exertional malaise: General | Worsen | 2.74 |
Post-exertional malaise: Mentally tired after the slightest effort | Worsen | 2.74 |
Post-exertional malaise: Physically drained or sick after mild activity | Worsen | 2.74 |
Post-exertional malaise: Post-exertional malaise | Worsen | 2.74 |
Post-exertional malaise: Rapid cognitive fatigability, | Worsen | 2.74 |
Post-exertional malaise: Worsening of symptoms after mild mental activity | Worsen | 2.74 |
We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is according to the microbiome shifts reported in studies. Clinical studies may show different results
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Allergies | Worsen | 2.61 |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | Worsen | 2.74 |
Ankylosing spondylitis | Worsen | 3.91 |
Asthma | Worsen | 2.74 |
Atherosclerosis | Improves | -3.87 |
Autism | Worsen | 0.19 |
Brain Trauma | Improves | -2.74 |
Carcinoma | Improves | -2.41 |
Celiac Disease | Improves | -3.1 |
Chronic Fatigue Syndrome | Improves | -2.43 |
Chronic Kidney Disease | Improves | -2.41 |
Chronic urticaria (Hives) | Improves | -3.06 |
Colorectal Cancer | Improves | -2.25 |
Crohn's Disease | Improves | -4.73 |
cystic fibrosis | Improves | -3.57 |
Depression | Improves | -3 |
Epilepsy | Improves | -2.54 |
Generalized anxiety disorder | Improves | -3.82 |
Graves' disease | Worsen | 2.74 |
High Blood Pressure | Worsen | 2.54 |
Histamine Issues | Improves | -3.86 |
IgA nephropathy (IgAN) | Improves | -1.35 |
Inflammatory Bowel Disease | Improves | -4.77 |
Irritable Bowel Syndrome | Improves | -4.23 |
Liver Cirrhosis | Improves | -3.69 |
ME/CFS with IBS | Worsen | 0 |
ME/CFS without IBS | Improves | -2.43 |
Mood Disorders | Improves | -2.74 |
Multiple Sclerosis | Improves | -2.43 |
neuropsychiatric disorders (PANDAS, PANS) | Improves | -2.42 |
Obesity | Improves | -3.24 |
Osteoporosis | Improves | -2.41 |
Parkinson's Disease | Improves | -2.74 |
Psoriasis | Improves | -3.44 |
Rheumatoid arthritis | Improves | -2.25 |
rheumatoid arthritis (RA),Spondyloarthritis (SpA) | Improves | -3.53 |
Schizophrenia | Worsen | 2.74 |
Sjögren syndrome | Improves | -2.41 |
Small Intestinal Bacterial Overgrowth (SIBO) | Improves | -3.95 |
Stress / posttraumatic stress disorder | Improves | -4.78 |
Type 1 Diabetes | Worsen | 2.48 |
Type 2 Diabetes | Improves | -3.32 |
Ulcerative colitis | Improves | -3.5 |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.