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    Citizen Science Infered Impact

    We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

    This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

    SymptomImpactPredictor of Bacteria Shift
    Comorbid-Mouth: Dry MouthWorsen2.74
    DePaul University Fatigue Questionnaire : AllergiesWorsen2.8
    DePaul University Fatigue Questionnaire : Anxiety/tensionWorsen2.8
    DePaul University Fatigue Questionnaire : FatigueWorsen2.8
    DePaul University Fatigue Questionnaire : Forgetting what you are trying to sayWorsen2.8
    DePaul University Fatigue Questionnaire : Walking up early in the morning (e.g. 3AM)Worsen2.8
    Neuroendocrine: Feeling like you have a low temperatureWorsen2.74
    Neurological: emotional overloadWorsen2.74
    Neurological: fasciculations Worsen2.74
    Neurological: High degree of Empathy before onsetWorsen2.74
    Neurological: Short-term memory issuesWorsen2.74
    Neurological: Spatial instability and disorientationWorsen2.74
    Post-exertional malaise: GeneralWorsen2.74
    Post-exertional malaise: Mentally tired after the slightest effortWorsen3.48
    Post-exertional malaise: Physically drained or sick after mild activityWorsen2.74
    Post-exertional malaise: Post-exertional malaiseWorsen2.74
    Post-exertional malaise: Rapid cognitive fatigability, Worsen2.74
    Post-exertional malaise: Worsening of symptoms after mild mental activityWorsen2.74

    Published Science Infered Impact

    We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

    This is according to the microbiome shifts reported in studies. Clinical studies may show different results

    SymptomImpactPredictor of Bacteria Shift
    AcneImproves-3.47
    ADHDWorsen3.56
    AllergiesImproves-2.39
    Alzheimer's diseaseImproves-3.56
    Amyotrophic lateral sclerosis (ALS) Motor NeuronWorsen2.74
    Ankylosing spondylitisWorsen3.25
    AsthmaWorsen3.48
    AtherosclerosisWorsen2.89
    AutismImproves-4.48
    Barrett esophagus cancerWorsen1.46
    Brain TraumaWorsen1.29
    CarcinomaWorsen1.32
    Celiac DiseaseImproves-3.34
    Chronic Fatigue SyndromeImproves-4.43
    Chronic Kidney DiseaseImproves-3.14
    Chronic urticaria (Hives)Improves-3.06
    Colorectal CancerImproves-4.32
    Crohn's DiseaseImproves-3.02
    cystic fibrosisWorsen2.39
    DepressionWorsen3.15
    EpilepsyImproves-3.01
    FibromyalgiaImproves-3.47
    gallstone disease (gsd)Improves-0.86
    Gastroesophageal reflux disease (Gerd) including Barrett's esophagusImproves-1.46
    Generalized anxiety disorderImproves-2.86
    Graves' diseaseWorsen2.74
    Hashimoto's thyroiditisImproves-3.51
    High Blood PressureImproves-3.38
    Histamine IssuesWorsen1.58
    Histamine Issues From UbiomeImproves-2.72
    Hyperlipidemia (High Blood Fats)Improves-2.63
    IgA nephropathy (IgAN)Improves-4.07
    Inflammatory Bowel DiseaseWorsen1.55
    Irritable Bowel SyndromeImproves-5.09
    Liver CirrhosisImproves-4.05
    ME/CFS with IBSImproves-2.88
    ME/CFS without IBSImproves-2.88
    Mood DisordersImproves-2.74
    Multiple SclerosisWorsen1.3
    Multiple system atrophy (MSA)Improves-1.3
    neuropsychiatric disorders (PANDAS, PANS)Improves-2.42
    Nonalcoholic Fatty Liver Disease (nafld) NonalcoholicImproves-3.05
    ObesityWorsen2.14
    OsteoporosisWorsen1.63
    Parkinson's DiseaseWorsen4.58
    PsoriasisWorsen2.96
    Rheumatoid arthritisImproves-3.83
    rheumatoid arthritis (RA),Spondyloarthritis (SpA)Worsen4.04
    RosaceaWorsen1.3
    SchizophreniaWorsen4.11
    Sjögren syndromeImproves-3.33
    Small Intestinal Bacterial Overgrowth (SIBO)Worsen1.63
    Stress / posttraumatic stress disorderWorsen2.4
    Systemic Lupus ErythematosusImproves-2.88
    Type 1 DiabetesImproves-2.72
    Type 2 DiabetesWorsen2.74
    Ulcerative colitisImproves-2.67

    Bacteria Impacted

    Suggest a missed study:

    We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

    📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
    Taxonomy Rank Effect Citations
    Enterobacteriaceae family Decreases 📓 Source Study
    Bifidobacteriaceae family Increases 📓 Source Study
    Enterococcaceae family Increases 📓 Source Study
    Lactobacillaceae family Increases 📓 Source Study
    Escherichia genus Decreases 📓 Source Study
    Escherichia genus Decreases 📓 Source Study
    Kluyvera genus Decreases 📓 Source Study
    Kluyvera genus Decreases 📓 Source Study
    Atlantibacter genus Decreases 👪 Source Study
    Biostraticola genus Decreases 👪 Source Study
    Buttiauxella genus Decreases 👪 Source Study
    Candidatus Ishikawaella genus Decreases 👪 Source Study
    Cedecea genus Decreases 👪 Source Study
    Gibbsiella genus Decreases 👪 Source Study
    Kosakonia genus Decreases 👪 Source Study
    Leclercia genus Decreases 👪 Source Study
    Lelliottia genus Decreases 👪 Source Study
    Limnobaculum genus Decreases 👪 Source Study
    Metakosakonia genus Decreases 👪 Source Study
    Moranella genus Decreases 👪 Source Study
    Pluralibacter genus Decreases 👪 Source Study
    Pseudescherichia genus Decreases 👪 Source Study
    Raoultella genus Decreases 👪 Source Study
    Riesia genus Decreases 👪 Source Study
    Rosenbergiella genus Decreases 👪 Source Study
    Shimwellia genus Decreases 👪 Source Study
    Siccibacter genus Decreases 👪 Source Study
    Yokenella genus Decreases 👪 Source Study
    Aeriscardovia genus Increases 👪 Source Study
    Alloscardovia genus Increases 👪 Source Study
    Burkholderia cepacia complex genus Increases 👪 Source Study
    Catellicoccus genus Increases 👪 Source Study
    Gardnerella genus Increases 👪 Source Study
    Melissococcus genus Increases 👪 Source Study
    Neoscardovia genus Increases 👪 Source Study
    Parascardovia genus Increases 👪 Source Study
    Pediococcus genus Increases 👪 Source Study
    Pilibacter genus Increases 👪 Source Study
    pseudomallei group genus Increases 👪 Source Study
    Pseudoscardovia genus Increases 👪 Source Study
    Scardovia genus Increases 👪 Source Study
    Sharpea genus Increases 👪 Source Study
    Tetragenococcus genus Increases 👪 Source Study
    Vagococcus genus Increases 👪 Source Study
    Bifidobacterium genus Increases 📓 Source Study
    Burkholderia genus Increases 📓 Source Study
    Enterococcus genus Increases 📓 Source Study
    Enterococcus genus Increases 📓 Source Study
    Klebsiella genus Increases 📓 Source Study
    Lactobacillus genus Increases 📓 Source Study
    Escherichia coli species Decreases 📓 Source Study
    Escherichia coli species Decreases 📓 Source Study
    ATCC 33110 species Decreases 👪 Source Study
    ATCC 35469 species Decreases 👪 Source Study
    Escherichia albertii species Decreases 👪 Source Study
    Escherichia citrophila (Asai et al. 1957) Asai et al. 1962 species Decreases 👪 Source Study
    Escherichia coli Biovare species Decreases 👪 Source Study
    Escherichia marmotae species Decreases 👪 Source Study
    Escherichia sp. species Decreases 👪 Source Study
    Escherichia sp. 1_1_43 species Decreases 👪 Source Study
    Escherichia sp. 4_1_40B species Decreases 👪 Source Study
    Kluyvera ascorbata species Decreases 👪 Source Study
    Kluyvera georgiana species Decreases 👪 Source Study
    Kluyvera sp. SR5.1 species Decreases 👪 Source Study
    ATCC 10248 species Increases 👪 Source Study
    ATCC 25258 species Increases 👪 Source Study
    ATCC 33199 species Increases 👪 Source Study
    ATCC 33617 species Increases 👪 Source Study
    ATCC 35046 species Increases 👪 Source Study
    ATCC 43733 species Increases 👪 Source Study
    ATCC 49062 species Increases 👪 Source Study
    ATCC 49372 species Increases 👪 Source Study
    ATCC 49427 species Increases 👪 Source Study
    ATCC 51266 species Increases 👪 Source Study
    ATCC 700211 species Increases 👪 Source Study
    ATCC 700308 species Increases 👪 Source Study
    ATCC 700934 species Increases 👪 Source Study
    ATCC 8041 species Increases 👪 Source Study
    ATCC BAA-1240 species Increases 👪 Source Study
    ATCC BAA-2403 species Increases 👪 Source Study
    ATCC BAA-350 species Increases 👪 Source Study
    BCRC 17755 species Increases 👪 Source Study
    Bifidobacterium actinocoloniiforme species Increases 👪 Source Study
    Bifidobacterium angulatum species Increases 👪 Source Study
    Bifidobacterium avesanii species Increases 👪 Source Study
    Bifidobacterium cuniculi species Increases 👪 Source Study
    Bifidobacterium lemurum species Increases 👪 Source Study
    Bifidobacterium sp. 113 species Increases 👪 Source Study
    Bifidobacterium sp. group II-3 species Increases 👪 Source Study
    Bifidobacterium sp. h12 species Increases 👪 Source Study
    Bifidobacterium sp. JCM 6439 species Increases 👪 Source Study
    Bifidobacterium sp. M45 species Increases 👪 Source Study
    Bifidobacterium sp. MC_8 species Increases 👪 Source Study
    Bifidobacterium sp. PL1 species Increases 👪 Source Study
    Burkholderia cordobensis YI23 species Increases 👪 Source Study
    Burkholderia insecticola species Increases 👪 Source Study
    Burkholderia sp. AD24 species Increases 👪 Source Study
    Burkholderia sp. Bp7605 species Increases 👪 Source Study
    Burkholderia sp. CBPB-HIM species Increases 👪 Source Study
    Burkholderia sp. CCGE1003 species Increases 👪 Source Study
    Burkholderia sp. IDO3 species Increases 👪 Source Study
    Burkholderia sp. JP2-270 species Increases 👪 Source Study
    Burkholderia sp. JSC-R3-522-9 species Increases 👪 Source Study
    Burkholderia sp. KK1 species Increases 👪 Source Study
    Burkholderia sp. OLGA172 species Increases 👪 Source Study
    Burkholderia sp. PAMC 26561 species Increases 👪 Source Study
    Burkholderia ultramafica species Increases 👪 Source Study
    CCM 7299 species Increases 👪 Source Study
    CCTCC M 2011381 species Increases 👪 Source Study
    CCUG 48456 species Increases 👪 Source Study
    CCUG 48460 species Increases 👪 Source Study
    CCUG 53174 species Increases 👪 Source Study
    CCUG 59304 species Increases 👪 Source Study
    CCUG 63301 species Increases 👪 Source Study
    CCUG 63631 species Increases 👪 Source Study
    CGMCC 1.15942 species Increases 👪 Source Study
    CIP 106922 species Increases 👪 Source Study
    CIP 110771 species Increases 👪 Source Study
    CRBIP 24.179 species Increases 👪 Source Study
    DSM 16230 species Increases 👪 Source Study
    DSM 19284 species Increases 👪 Source Study
    DSM 19907 species Increases 👪 Source Study
    DSM 24301 species Increases 👪 Source Study
    DSM 26202 species Increases 👪 Source Study
    DSM 28069 species Increases 👪 Source Study
    Enterococcus alcedinis species Increases 👪 Source Study
    Enterococcus asini species Increases 👪 Source Study
    Enterococcus canis species Increases 👪 Source Study
    Enterococcus cecorum species Increases 👪 Source Study
    Enterococcus columbae species Increases 👪 Source Study
    enterococcus durans species Increases 👪 Source Study
    Enterococcus gallinarum species Increases 👪 Source Study
    Enterococcus haemoperoxidus species Increases 👪 Source Study
    Enterococcus hermanniensis species Increases 👪 Source Study
    Enterococcus italicus species Increases 👪 Source Study
    Enterococcus malodoratus species Increases 👪 Source Study
    Enterococcus sp. species Increases 👪 Source Study
    Enterococcus sp. FDAARGOS_375 species Increases 👪 Source Study
    Enterococcus sp. HSIEG1 species Increases 👪 Source Study
    Enterococcus sulfureus species Increases 👪 Source Study
    JCM 1039 species Increases 👪 Source Study
    JCM 11969 species Increases 👪 Source Study
    JCM 18665 species Increases 👪 Source Study
    JCM 31938 species Increases 👪 Source Study
    JCM 32269 species Increases 👪 Source Study
    JCM 8722 species Increases 👪 Source Study
    Klebsiella sp. species Increases 👪 Source Study
    Klebsiella sp. B12 species Increases 👪 Source Study
    Klebsiella sp. FDAARGOS_511 species Increases 👪 Source Study
    Klebsiella sp. M5al species Increases 👪 Source Study
    Klebsiella sp. OBRC7 species Increases 👪 Source Study
    Klebsiella sp. SOR89 species Increases 👪 Source Study
    Klebsiella sp. WCHKl090001 species Increases 👪 Source Study
    Klebsiella variicola species Increases 👪 Source Study
    Lactobacillus acetotolerans species Increases 👪 Source Study
    Lactobacillus acidipiscis species Increases 👪 Source Study
    Lactobacillus agilis species Increases 👪 Source Study
    Lactobacillus alimentarius species Increases 👪 Source Study
    Lactobacillus amylolyticus species Increases 👪 Source Study
    Lactobacillus apis species Increases 👪 Source Study
    Lactobacillus bifermentans species Increases 👪 Source Study
    Lactobacillus bombi species Increases 👪 Source Study
    Lactobacillus brantae species Increases 👪 Source Study
    Lactobacillus ceti species Increases 👪 Source Study
    Lactobacillus coleohominis species Increases 👪 Source Study
    Lactobacillus composti species Increases 👪 Source Study
    Lactobacillus coryniformis species Increases 👪 Source Study
    Lactobacillus equi species Increases 👪 Source Study
    Lactobacillus equigenerosi species Increases 👪 Source Study
    Lactobacillus fermentum species Increases 👪 Source Study
    Lactobacillus floricola species Increases 👪 Source Study
    Lactobacillus fuchuensis species Increases 👪 Source Study
    Lactobacillus hamsteri species Increases 👪 Source Study
    Lactobacillus harbinensis species Increases 👪 Source Study
    Lactobacillus hayakitensis species Increases 👪 Source Study
    Lactobacillus helveticus species Increases 👪 Source Study
    Lactobacillus hilgardii species Increases 👪 Source Study
    Lactobacillus ingluviei species Increases 👪 Source Study
    Lactobacillus intestinalis species Increases 👪 Source Study
    Lactobacillus johnsonii species Increases 👪 Source Study
    Lactobacillus kalixensis species Increases 👪 Source Study
    Lactobacillus kefiranofaciens species Increases 👪 Source Study
    lactobacillus kefiri species Increases 👪 Source Study
    Lactobacillus lindneri species Increases 👪 Source Study
    Lactobacillus malefermentans species Increases 👪 Source Study
    Lactobacillus mellifer species Increases 👪 Source Study
    Lactobacillus mellis species Increases 👪 Source Study
    Lactobacillus murinus species Increases 👪 Source Study
    Lactobacillus namurensis species Increases 👪 Source Study
    Lactobacillus nodensis species Increases 👪 Source Study
    Lactobacillus oligofermentans species Increases 👪 Source Study
    Lactobacillus oryzae species Increases 👪 Source Study
    Lactobacillus ozensis species Increases 👪 Source Study
    Lactobacillus pantheris species Increases 👪 Source Study
    Lactobacillus parabuchneri species Increases 👪 Source Study
    Lactobacillus parafarraginis species Increases 👪 Source Study
    Lactobacillus paralimentarius species Increases 👪 Source Study
    Lactobacillus perolens species Increases 👪 Source Study
    Lactobacillus plajomi species Increases 👪 Source Study
    Lactobacillus pontis species Increases 👪 Source Study
    Lactobacillus psittaci species Increases 👪 Source Study
    Lactobacillus rodentium species Increases 👪 Source Study
    Lactobacillus sakei species Increases 👪 Source Study
    Lactobacillus selangorensis species Increases 👪 Source Study
    Lactobacillus songhuajiangensis species Increases 👪 Source Study
    Lactobacillus sp. species Increases 👪 Source Study
    Lactobacillus sp. 7_1_47FAA species Increases 👪 Source Study
    Lactobacillus sp. Akhmro1 species Increases 👪 Source Study
    Lactobacillus sp. BHWM-4 species Increases 👪 Source Study
    Lactobacillus sp. C30An8 species Increases 👪 Source Study
    Lactobacillus sp. C4I1 species Increases 👪 Source Study
    Lactobacillus sp. C4I18 species Increases 👪 Source Study
    Lactobacillus sp. CBA3606 species Increases 👪 Source Study
    Lactobacillus sp. H7_2_4MCO2 species Increases 👪 Source Study
    Lactobacillus sp. H7_6_6MCO2 species Increases 👪 Source Study
    Lactobacillus sp. HBUAS52074 species Increases 👪 Source Study
    Lactobacillus sp. HSLZ-75 species Increases 👪 Source Study
    Lactobacillus sp. MYMRS/TEN2 species Increases 👪 Source Study
    Lactobacillus sp. NRCT-KU 1 species Increases 👪 Source Study
    Lactobacillus sp. S16 species Increases 👪 Source Study
    Lactobacillus sp. T059 species Increases 👪 Source Study
    Lactobacillus sp. TAB-22 species Increases 👪 Source Study
    Lactobacillus sp. TAB-29 species Increases 👪 Source Study
    Lactobacillus tucceti species Increases 👪 Source Study
    Lactobacillus vaccinostercus species Increases 👪 Source Study
    Lactobacillus vaginalis species Increases 👪 Source Study
    Lactobacillus vini species Increases 👪 Source Study
    Lactobacillus yamanashiensis species Increases 👪 Source Study
    Lactobacillus zymae species Increases 👪 Source Study
    Lactobacterium buchneri species Increases 👪 Source Study
    LMG:9200 species Increases 👪 Source Study
    LMG:9496 species Increases 👪 Source Study
    not JCM 16719 species Increases 👪 Source Study
    PCU:282 species Increases 👪 Source Study

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