ofloxacin (antibiotic)s ** full range

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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

Symptom	Impact	Predictor of Bacteria Shift
DePaul University Fatigue Questionnaire : Difficulty staying asleep	Improves	-2.83
Neurological: Executive Decision Making (Difficulty making)	Worsen	2.42
Neurological: Impairment of concentration	Worsen	2.42

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

Symptom	Impact	Predictor of Bacteria Shift
Acne	Improves	-3.3
Allergic Rhinitis (Hay Fever)	Improves	-2.41
Allergies	Improves	-1.17
Alzheimer's disease	Worsen	0
Amyotrophic lateral sclerosis (ALS) Motor Neuron	Improves	-3.85
Ankylosing spondylitis	Worsen	3.9
Asthma	Worsen	0
Atherosclerosis	Improves	-4.27
Autism	Worsen	3.24
Bipolar Disorder	Improves	-3.14
Brain Trauma	Improves	-0.61
Carcinoma	Improves	-3.18
Celiac Disease	Improves	-3.63
Chronic Fatigue Syndrome	Improves	-3.58
Chronic Kidney Disease	Improves	-3.02
Chronic Urticaria (Hives)	Improves	-1.68
Colorectal Cancer	Improves	-3.13
COVID-19	Improves	-3.43
Crohn's Disease	Improves	-4.17
cystic fibrosis	Improves	-3.57
Depression	Worsen	2.88
Eczema	Improves	-1.52
Functional constipation / chronic idiopathic constipation	Worsen	1.36
Generalized anxiety disorder	Improves	-3.92
Hashimoto's thyroiditis	Improves	-2.42
High Blood Pressure	Worsen	1.98
Histamine Issues	Improves	-4.58
Inflammatory Bowel Disease	Improves	-4.82
Irritable Bowel Syndrome	Improves	-2.41
Liver Cirrhosis	Improves	-4.71
ME/CFS without IBS	Improves	-2.43
Multiple Sclerosis	Worsen	4.06
neuropsychiatric disorders (PANDAS, PANS)	Improves	-2.42
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic	Improves	-3.48
Obesity	Improves	-4.31
Osteoarthritis	Improves	-2.41
Osteoporosis	Improves	-3.02
Parkinson's Disease	Worsen	4.11
Psoriasis	Improves	-1.4
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	Improves	-4.3
Rosacea	Worsen	2.44
Schizophrenia	Worsen	1.35
Sjögren syndrome	Improves	-3.02
Small Intestinal Bacterial Overgrowth (SIBO)	Improves	-3.92
Stress / posttraumatic stress disorder	Improves	-4.22
Systemic Lupus Erythematosus	Improves	-3.9
Type 1 Diabetes	Improves	-1.64
Type 2 Diabetes	Improves	-4.84
Ulcerative colitis	Improves	-4.5

Bacteria Impacted

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.