clindamycin (antibiotic)s ** full range

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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

Symptom	Impact	Predictor of Bacteria Shift
Age: 0-10	Worsen	3.56
Autonomic Manifestations: cardiac arrhythmias	Worsen	2.83
Comorbid: Fibromyalgia	Improves	-2.96
DePaul University Fatigue Questionnaire : Allergies	Worsen	2.51
DePaul University Fatigue Questionnaire : Difficulty staying asleep	Improves	-2.83
DePaul University Fatigue Questionnaire : Fatigue	Improves	-1.93
DePaul University Fatigue Questionnaire : Walking up early in the morning (e.g. 3AM)	Improves	-1.93
Immune Manifestations: Inflammation (General)	Improves	-3.24
Joint: Tenderness	Improves	-2.97
Neuroendocrine Manifestations: Excessive adrenaline	Improves	-2.9
Neurological: Confusion	Worsen	2.97
Official Diagnosis: Autoimmune Disease	Improves	-2.97
Pain: Sensitivity to pain	Improves	-1.71
Post-exertional malaise: Mentally tired after the slightest effort	Improves	-3.56

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

Symptom	Impact	Predictor of Bacteria Shift
Acne	Worsen	3.57
ADHD	Improves	-4.57
Allergic Rhinitis (Hay Fever)	Improves	-2.43
Allergies	Improves	-2.8
Alzheimer's disease	Worsen	3.68
Amyotrophic lateral sclerosis (ALS) Motor Neuron	Improves	-3.78
Ankylosing spondylitis	Worsen	3.43
Asthma	Improves	-3.82
Atherosclerosis	Improves	-4.11
Autism	Worsen	5.14
Barrett esophagus cancer	Worsen	1.8
Bipolar Disorder	Improves	-2.61
Brain Trauma	Improves	-1.98
Carcinoma	Improves	-3.98
Celiac Disease	Worsen	2.42
Cerebral Palsy	Improves	-3.93
Chronic Fatigue Syndrome	Improves	-1.99
Chronic Kidney Disease	Improves	-2.6
Chronic Urticaria (Hives)	Improves	-3.34
Colorectal Cancer	Improves	-4.6
COVID-19	Improves	-3.62
Crohn's Disease	Improves	-4.11
cystic fibrosis	Improves	-3.57
Depression	Improves	-3.41
Epilepsy	Worsen	0.63
Fibromyalgia	Worsen	4.52
Functional constipation / chronic idiopathic constipation	Improves	-3.42
gallstone disease (gsd)	Worsen	2.45
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus	Worsen	1.98
Generalized anxiety disorder	Improves	-3.47
Graves' disease	Improves	-2.96
Hashimoto's thyroiditis	Worsen	2.04
High Blood Pressure	Worsen	3.04
Histamine Issues	Improves	-3.47
hypercholesterolemia (High Cholesterol)	Worsen	2.69
Hyperlipidemia (High Blood Fats)	Improves	-2.88
IgA nephropathy (IgAN)	Worsen	3.56
Inflammatory Bowel Disease	Improves	-3.66
Irritable Bowel Syndrome	Worsen	4.03
Liver Cirrhosis	Improves	-4.49
ME/CFS with IBS	Improves	-3.5
ME/CFS without IBS	Improves	-4.37
Multiple Sclerosis	Improves	-3.37
Multiple system atrophy (MSA)	Worsen	2.88
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic	Improves	-3.3
NonCeliac Gluten Sensitivity	Worsen	2.88
Obesity	Improves	-3.74
Osteoarthritis	Improves	-3.79
Osteoporosis	Improves	-3.34
Parkinson's Disease	Improves	-4.73
Psoriasis	Improves	-4.77
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	Improves	-3.05
Rosacea	Worsen	2.2
Schizophrenia	Worsen	3.78
Sjögren syndrome	Worsen	1.9
Small Intestinal Bacterial Overgrowth (SIBO)	Improves	-4.08
Stress / posttraumatic stress disorder	Improves	-4.54
Systemic Lupus Erythematosus	Improves	-4.34
Type 1 Diabetes	Worsen	4.05
Type 2 Diabetes	Improves	-1.38
Ulcerative colitis	Improves	-2.55

Bacteria Impacted

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.