Roseburia faecis Details: NCBI 301302, gram-negative or unknown [species]

| DSM 16840| NCIMB 14031| Roseburia faecis| Roseburia faecis Duncan et al. 2006| strain M72/1

1. Butyrate Production:

   • Roseburia species, including Roseburia faecis, are butyrate-producing bacteria. Butyrate is a short-chain fatty acid that serves as an energy source for the cells lining the colon and is associated with various health benefits. Butyrate has anti-inflammatory properties and is important for maintaining the health of the intestinal epithelium.

2. Gut Health:

   • Butyrate is known for its role in promoting gut health. It helps to maintain the integrity of the intestinal barrier, which is essential for preventing the leakage of harmful substances from the gut into the bloodstream. A healthy gut barrier is crucial for overall immune function and protection against inflammatory conditions.

3. Anti-Inflammatory Effects:

   • Butyrate has anti-inflammatory effects in the gut, and it can help modulate the immune response. Chronic inflammation in the gut is associated with various gastrointestinal conditions, and the presence of butyrate-producing bacteria like Roseburia faecis may contribute to a balanced inflammatory response.

4. Dietary Fiber Fermentation:

   • Roseburia faecis, like other Roseburia species, is involved in the fermentation of dietary fibers. The breakdown of complex carbohydrates by these bacteria produces SCFAs, including butyrate. A diet rich in fiber provides substrates for these bacteria, supporting their growth and activity.

5. Associations with Health Conditions:

   • Changes in the abundance or activity of Roseburia species, including Roseburia faecis, have been observed in studies of the gut microbiota in various health conditions. Imbalances in the gut microbiota are associated with conditions such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and metabolic disorders.

6. Metabolic Health:

   • Butyrate has been associated with metabolic health benefits. It can influence insulin sensitivity and energy metabolism, potentially playing a role in metabolic disorders such as obesity and type 2 diabetes.

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Roseburia faecis

• Frequency - how often do samples show this bacteria
• UD - An alternative statistical algorithm (which factors in the frequency)
• Kaltoft-Moldrup Heuristic Using uploaded data
• Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)

Lab	Frequency	UD-Low	UD-High	KM Low	KM High	Lab Low	Lab High	Mean	Median	Standard Deviation	Box Plot Low	Box Plot High	KM Percentile Low	KM Percentile High
Other Labs	1.68			17	42660	0	34931	9524.7	3340	12962.5	0	22618	0 %ile	100 %ile
biomesight	92.41	0	20170	720	22740	0	56634	13724.8	6490	21892.7	0	25990	9.9 %ile	91 %ile
thryve	88.54	0	5727	51	9271	0	33284	5919.5	647	13961.6	0	10383	11.5 %ile	90.7 %ile
ubiome	73.38	0	23909	958	139525	0	72882	23889.5	17910	24996.3	0	50196	8 %ile	100 %ile

External Reference Ranges for Roseburia faecis

Roseburia faecis (NCBI 301302) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age

Statistic by Lab Source for Roseburia faecis

These desired values are reported from the lab reports

Lab	Frequency Seen	Average	Standard Deviation	Sample Count	Lab Samples
BiomeSight	98.683 %	1.312 %	2.128 %	2923.0	2962
BiomeSightRdp	29.032 %	3.828 %	4.452 %	9.0	31
bugspeak	100 %	2.178 %	%	1.0	1
CosmosId	28.125 %	0.557 %	1.005 %	9.0	32
custom	21.311 %	1.522 %	1.769 %	13.0	61
Medivere	100 %	0.674 %	0.683 %	7.0	7
Microba	10.714 %	0.617 %	0.52 %	3.0	28
SequentiaBiotech	11.111 %	0.156 %	0.18 %	4.0	36
Thryve	87.977 %	0.67 %	1.879 %	1222.0	1389
Tiny	100 %	0.013 %	%	1.0	1
uBiome	73.106 %	2.396 %	2.502 %	579.0	792

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Data Contradictions — Limits of Certainity

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General Substance	Specific Substance	Effect
Amino Acid and similar	Conjugated Linoleic Acid	1 Studies recorded. The consensus is Increases📓, Click for details.
Amino Acid and similar	punicic acid	1 Studies recorded. The consensus is Increases📓, Click for details.
Antibiotics, Antivirals etc	amoxicillin (antibiotic)s[CFS]	1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc	Rapamycin	1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc	rifaximin (antibiotic)s	2 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc	tetracycline (antibiotic)s	1 Studies recorded. The consensus is Increases📓, Click for details.
Antibiotics, Antivirals etc	trimethoprim (antibiotic)s	1 Studies recorded. The consensus is Increases📓, Click for details.
Diet Style	dietary fiber	1 Studies recorded. The consensus is Increases👶, Click for details.
Diet Style	fibre-rich macrobiotic ma-pi 2 diet	1 Studies recorded. The consensus is Increases📓, Click for details.
Diet Style	gluten-free diet	1 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	high animal protein diet	1 Studies recorded. The consensus is Decreases👶, Click for details.
Diet Style	high fiber diet	2 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	high-fat diets	1 Studies recorded. The consensus is Increases📓, Click for details.
Diet Style	high-protein diet	1 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	ketogenic diet	1 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	low carbohydrate diet	2 Studies recorded. The consensus is Decreases👶📓, Click for details.
Diet Style	low-fat diets	1 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	low-fat high-complex carbohydrate diet	1 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	mediterranean diet	1 Studies recorded. The consensus is Increases📓, Click for details.
Drug or "Non-drug"	epinephrine	1 Studies recorded. The consensus is Decreases👶, Click for details.
flavonoids, polyphenols etc	Methionine	1 Studies recorded. The consensus is Decreases📓, Click for details.
flavonoids, polyphenols etc	nobiletin	1 Studies recorded. The consensus is Increases📓, Click for details.
flavonoids, polyphenols etc	polyphenols	1 Studies recorded. The consensus is Increases📓, Click for details.
flavonoids, polyphenols etc	quercetin,resveratrol	1 Studies recorded. The consensus is Decreases📓, Click for details.
flavonoids, polyphenols etc	resveratrol (grape seed/polyphenols/red wine)	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	almonds/ almond skins	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	barley	4 Studies recorded. The consensus is Increases👶📓, Click for details.
Food (excluding seasonings)	barley,oat	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	blueberry	2 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	cranberry bean flour	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	gluten	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	Goji (berry,juice)	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	high red meat	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	laminaria digitata,oarweed - seaweed	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	linseed(flaxseed)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	lupin seeds (anaphylaxis risk, toxic if not prepared properly)	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	nuts	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	omega-3 fatty acids	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Oyster Mushroom	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	pea (fiber, protein)	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	Peanut	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	pectin	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	Pork	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	Pulses	2 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	soy	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	vegetarians	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	walnuts	3 Studies recorded. The consensus is Increases👶📓, Click for details.
Food (excluding seasonings)	wheat	3 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	wheat bran	2 Studies recorded. The consensus is Increases👶📓, Click for details.
Food (excluding seasonings)	white button mushrooms	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	whole grain,bran	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	whole-grain barley	1 Studies recorded. The consensus is Increases📓, Click for details.
Herb or Spice	Baicalin	1 Studies recorded. The consensus is Increases📓, Click for details.
Herb or Spice	berberine	2 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	cannabinoids	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	cinnamon (oil. spice)	1 Studies recorded. The consensus is Increases📓, Click for details.
Herb or Spice	Citrus Fruit Extract	1 Studies recorded. The consensus is Increases📓, Click for details.
Herb or Spice	Moringa Oleifera	1 Studies recorded. The consensus is Increases📓, Click for details.
Herb or Spice	polygonatum kingianum(Orange Flower Solomon's Seal.)	1 Studies recorded. The consensus is Increases📓, Click for details.
Herb or Spice	Shen Ling Bai Zhu San	1 Studies recorded. The consensus is Increases📓, Click for details.
Herb or Spice	Slippery Elm	2 Studies recorded. The consensus is Increases👶, Click for details.
Prebiotics and similar	arabinogalactan (prebiotic)	3 Studies recorded. The consensus is Increases📓, Click for details.
Prebiotics and similar	chitooligosaccharides (prebiotic)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar	fructo-oligosaccharides (prebiotic)	1 Studies recorded. The consensus is Decreases👶, Click for details.
Prebiotics and similar	galacto-oligosaccharides (prebiotic)	1 Studies recorded. The consensus is Increases📓, Click for details.
Prebiotics and similar	Human milk oligosaccharides (prebiotic, Holigos, Stachyose)	2 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar	inulin (prebiotic)	2 Studies recorded. The consensus is Increases📓, Click for details.
Prebiotics and similar	oligofructose-enriched inulin (prebiotic)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar	partially hydrolyzed guar gum	2 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar	Psyllium (Plantago Ovata Husk)	1 Studies recorded. The consensus is Increases📓, Click for details.
Prebiotics and similar	resistant starch	2 Studies recorded. The consensus is Increases👶📓, Click for details.
Prebiotics and similar	ß-glucan	1 Studies recorded. The consensus is Increases👶, Click for details.
Prebiotics and similar	xylan (prebiotic)	2 Studies recorded. The consensus is Increases📓, Click for details.
Prescription - Other	dopamine (prescription)	1 Studies recorded. The consensus is Increases👶, Click for details.
Prescription - Other	loperamide hydrochloride,(prescription)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Prescription - Other	polymannuronic acid	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	bacillus (probiotics)	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	bifidobacterium bifidum (probiotics)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	bifidobacterium longum bb536 (probiotics)	1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics	candida albicans (prescription)	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	lactobacillus acidophilus (probiotics)	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	lactobacillus paracasei (probiotics)	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	lactobacillus plantarum (probiotics)	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	lactobacillus rhamnosus (probiotics)	1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics	lactobacillus rhamnosus gg (probiotics)	2 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	lactobacillus salivarius (probiotics)	2 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	Limosilactobacillus fermentum (probiotic)	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	saccharomyces boulardii (probiotics)	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	spirulina(cyanobacteria)	1 Studies recorded. The consensus is Increases📓, Click for details.
Sugar and similar	chitosan,(sugar)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Sugar and similar	n-acetyl-d-glucosamine	1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar	Ferric citrate	1 Studies recorded. The consensus is Increases📓, Click for details.
Vitamins, Minerals and similar	fluorine	1 Studies recorded. The consensus is Decreases📓, Click for details.
Vitamins, Minerals and similar	iron	1 Studies recorded. The consensus is Increases📓, Click for details.
Vitamins, Minerals and similar	vitamin a	1 Studies recorded. The consensus is Increases📓, Click for details.
Vitamins, Minerals and similar	vitamin b2,Riboflavin	1 Studies recorded. The consensus is Decreases📓, Click for details.
Vitamins, Minerals and similar	Vitamin B9,folic acid	1 Studies recorded. The consensus is Decreases📓, Click for details.
Vitamins, Minerals and similar	Vitamin C (ascorbic acid)	1 Studies recorded. The consensus is Increases📓, Click for details.
Vitamins, Minerals and similar	vitamin d	2 Studies recorded. The consensus is Increases👶📓, Click for details.
Vitamins, Minerals and similar	Vitamin E	1 Studies recorded. The consensus is Increases📓, Click for details.

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