Akkermansiaceae Details: NCBI 1647988, gram-negative or unknown [family]

| Akkermansiaceae| Akkermansiaceae Hedlund and Derrien 2012

  1. Mucin Degradation:

    • Akkermansia muciniphila is recognized for its ability to degrade mucin, a component of the protective mucus layer that lines the gut. The degradation of mucin by Akkermansia may have implications for gut health and the maintenance of the intestinal barrier.
  2. Gut Barrier Function:

    • Akkermansia muciniphila has been associated with the maintenance of a healthy gut barrier. The mucin layer serves as a protective barrier, and its integrity is crucial for preventing the penetration of harmful substances and pathogens into the gut mucosa.
  3. Metabolic Effects:

    • Some studies suggest that Akkermansia muciniphila may have metabolic benefits. It has been associated with improvements in metabolic parameters such as insulin sensitivity, glucose metabolism, and lipid profile in animal models. These findings have led to investigations into the potential role of Akkermansia in metabolic disorders, including obesity and type 2 diabetes.
  4. Anti-Inflammatory Effects:

    • Akkermansia muciniphila has been studied for its potential anti-inflammatory properties. It may modulate immune responses and reduce inflammation in the gut. Chronic inflammation in the gut is associated with various diseases, and maintaining a balanced immune response is crucial for overall health.
  5. Associations with Diet:

    • Diet plays a role in shaping the composition of the gut microbiota, including the abundance of Akkermansia muciniphila. Diets rich in certain fibers, such as those found in fruits and vegetables, have been associated with increased abundance of Akkermansia.
  6. Potential Therapeutic Applications:

    • Due to its beneficial properties, researchers are exploring the therapeutic potential of Akkermansia muciniphila for various health conditions, including metabolic disorders, inflammatory bowel diseases, and other inflammatory conditions.

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Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Akkermansiaceae

Using Kaltoft-Moldrup Heuristic Using uploaded data for Akkermansiaceae

Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)
LabKM LowKM Percentile LowKM HighKM Percentile HighLab LowLab HighMean MedianStandard DeviationBox Plot LowBox Plot High
* 1 0 %ile 25460 92 %ile 0 70223 13546.2 1962 28916.7 0 39493
biomesight 10 0 %ile 16150 91 %ile 0 96205 14127.4 810 41876.3 0 17730
thorne 17 0 %ile 54600 100 %ile 0 25708 4070.1 135 11039.9 0 2683
thryve 32 8.1 %ile 23226 90.6 %ile 0 103980 17096.2 1304 44328.2 0 25954
ubiome 343 8 %ile 58152 91.6 %ile 0 133455 32707.5 10864 51401.6 0 75810
Lab Suggestions for Akkermansiaceae
Akkermansiaceae (NCBI 1647988) per million
Low Boundary High Boundary Low Boundary %age High Boundary %age Lab Samples
600 8600 0.06 0.86 Nirvana/CosmosId
21.48 6714.8 0.0021 0.6715 Thorne (20/80%ile)
Statistic by Lab Source for Akkermansiaceae
These desired values are reported from the lab reports
Lab Frequency Seen Average Standard Deviation Sample Count Lab Samples
AmericanGut 66.667 %   0.996 %  1.074 % 10.0 15
BiomeSight 82.096 %   1.396 %  4.121 % 2334.0 2843
BiomeSightRdp 28.125 %   1.417 %  2.277 % 9.0 32
bugspeak 100 %   0.005 %  % 1.0 1
CerbaLab 100 %   0.017 %  0.005 % 3.0 3
CosmosId 56.25 %   0.266 %  0.301 % 18.0 32
custom 44.068 %   1.671 %  2.047 % 26.0 59
es-xenogene 96.552 %   0.693 %  1.074 % 28.0 29
GanzimmunDiag 100 %   6.818 %  0 % 3.0 3
Medivere 28.571 %   0.002 %  0.001 % 2.0 7
Microba 35.714 %   1.855 %  5.013 % 10.0 28
Microba1 100 %   0.81 %  % 1.0 1
SequentiaBiotech 72.222 %   2.679 %  4.306 % 26.0 36
Thorne 82.353 %   0.23 %  0.796 % 70.0 85
Thryve 77.319 %   1.665 %  4.4 % 1067.0 1380
Tiny 100 %   0.001 %  % 1.0 1
uBiome 61.49 %   3.26 %  5.139 % 487.0 792

Symptoms Associated with Akkermansiaceae From Citizen Science Studies

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Data Contradictions β€” Limits of Certainity

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General Substance Specific Substance Effect
Amino Acid and similar acetic acid 1 Studies recorded. The consensus is Increases👪, Click for details.
Amino Acid and similar Conjugated Linoleic Acid 1 Studies recorded. The consensus is Increases👪, Click for details.
Amino Acid and similar Kaempferol 1 Studies recorded. The consensus is Increases👪, Click for details.
Amino Acid and similar melatonin supplement 1 Studies recorded. The consensus is Increases👪, Click for details.
Antibiotics, Antivirals etc azithromycin,(antibiotic)s[CFS] 1 Studies recorded. The consensus is Decreases👪, Click for details.
Antibiotics, Antivirals etc clindamycin (antibiotic)s[CFS] 1 Studies recorded. The consensus is Decreases👪, Click for details.
Antibiotics, Antivirals etc macrolide ((antibiotic)s) 1 Studies recorded. The consensus is Increases👪, Click for details.
Antibiotics, Antivirals etc minocycline (antibiotic)s[CFS] 2 Studies recorded. The consensus is Increases👪, Click for details.
Antibiotics, Antivirals etc vancomycin (antibiotic)[CFS] 1 Studies recorded. The consensus is Increases👪, Click for details.
Common Supplements colostrum 2 Studies recorded. The consensus is Increases👶, Click for details.
Common Supplements sodium butyrate 1 Studies recorded. The consensus is Increases👪, Click for details.
Common Supplements Tudca 1 Studies recorded. The consensus is Increases👪, Click for details.
Diet Style fibre-rich macrobiotic ma-pi 2 diet 1 Studies recorded. The consensus is Increases👪, Click for details.
Diet Style high sugar diet 3 Studies recorded. The consensus is Increases👶👪📓, Click for details.
Diet Style high-fat diets 4 Studies recorded. The consensus is Increases👶👪📓, Click for details.
Diet Style high-protein diet 2 Studies recorded. The consensus is Decreases👪, Click for details.
Diet Style ketogenic diet 2 Studies recorded. The consensus is Increases👪, Click for details.
Diet Style low carbohydrate diet 1 Studies recorded. The consensus is Increases👪, Click for details.
Diet Style low-fat diets 2 Studies recorded. The consensus is Increases👪, Click for details.
Diet Style mediterranean diet 1 Studies recorded. The consensus is Decreases👪, Click for details.
Diet Style Olive Oil 2 Studies recorded. The consensus is Increases👪, Click for details.
flavonoids, polyphenols etc Fisetin 1 Studies recorded. The consensus is Decreases👪, Click for details.
flavonoids, polyphenols etc grape polyphenols 1 Studies recorded. The consensus is Increases👪, Click for details.
flavonoids, polyphenols etc Pterostilbene 1 Studies recorded. The consensus is Increases👪, Click for details.
flavonoids, polyphenols etc quercetin,resveratrol 1 Studies recorded. The consensus is Increases👪, Click for details.
flavonoids, polyphenols etc red wine polyphenols 1 Studies recorded. The consensus is Increases👪, Click for details.
flavonoids, polyphenols etc resveratrol (grape seed/polyphenols/red wine) 5 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) apple 2 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) Astragalus 4 Studies recorded. The consensus is Increases👶👪📓, Click for details.
Food (excluding seasonings) barley 2 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) black raspberries 2 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) blueberry 1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) Caffeine 1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) capsaicin (hot pepper) 1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) Cheese 1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) cherry 1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) Cinnamaldehyde 1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) Cranberry 1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) cranberry bean flour 5 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) ethanol 1 Studies recorded. The consensus is Decreases👪, Click for details.
Food (excluding seasonings) fasting 2 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) fat 2 Studies recorded. The consensus is Decreases👪, Click for details.
Food (excluding seasonings) fish oil 1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) grapes 2 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) green tea 2 Studies recorded. The consensus is Decreases👪, Click for details.
Food (excluding seasonings) Kimchi 1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings) linseed(flaxseed) 1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) mulberry fruit polysaccharide 1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) pomegranate 3 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) red wine 2 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) rhubarb 1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) rye 1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) wheat 1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) wheat bran 1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings) whole grain,bran 1 Studies recorded. The consensus is Increases👪, Click for details.
Herb or Spice berberine 2 Studies recorded. The consensus is Increases👪, Click for details.
Herb or Spice Bofutsushosan 3 Studies recorded. The consensus is Increases👪📓, Click for details.
Herb or Spice cannabinoids 2 Studies recorded. The consensus is Increases👪, Click for details.
Herb or Spice cinnamon (oil. spice) 1 Studies recorded. The consensus is Increases👪, Click for details.
Herb or Spice Codonopsis pilosula 1 Studies recorded. The consensus is Increases👪, Click for details.
Herb or Spice Dangshen 1 Studies recorded. The consensus is Increases👪, Click for details.
Herb or Spice garlic (allium sativum) 2 Studies recorded. The consensus is Increases👶👪, Click for details.
Herb or Spice Ginseng 1 Studies recorded. The consensus is Increases👪, Click for details.
Herb or Spice glycyrrhizic acid (licorice) 1 Studies recorded. The consensus is Increases👪, Click for details.
Herb or Spice grape seed extract 2 Studies recorded. The consensus is Increases👪, Click for details.
Herb or Spice Papain 1 Studies recorded. The consensus is Increases👪, Click for details.
Herb or Spice Perilla frutescens(shiso) 1 Studies recorded. The consensus is Increases👪, Click for details.
Herb or Spice Rhubarb Peony Decoction 1 Studies recorded. The consensus is Increases👪, Click for details.
Herb or Spice Shen Ling Bai Zhu San 1 Studies recorded. The consensus is Increases👪, Click for details.
Herb or Spice triphala 1 Studies recorded. The consensus is Decreases👪, Click for details.
Miscellaneous, food additives, and other odd items bisphenol a (bpa) 1 Studies recorded. The consensus is Increases👪, Click for details.
Miscellaneous, food additives, and other odd items glycerol monolaurate (Monolaurin) 1 Studies recorded. The consensus is Decreases👪, Click for details.
Miscellaneous, food additives, and other odd items Polyethylene glycol 1 Studies recorded. The consensus is Increases👪, Click for details.
Not Classified Nitrogen Dioxide (Urban air pollutant) 1 Studies recorded. The consensus is Decreases👪, Click for details.
Prebiotics and similar arabinogalactan (prebiotic) 1 Studies recorded. The consensus is Increases👪, Click for details.
Prebiotics and similar chitooligosaccharides (prebiotic) 1 Studies recorded. The consensus is Increases👪, Click for details.
Prebiotics and similar fructo-oligosaccharides (prebiotic) 3 Studies recorded. The consensus is Increases👪, Click for details.
Prebiotics and similar galacto-oligosaccharides (prebiotic) 2 Studies recorded. The consensus is Decreases👪, Click for details.
Prebiotics and similar Glucomannan 1 Studies recorded. The consensus is Increases👪, Click for details.
Prebiotics and similar grape fiber 1 Studies recorded. The consensus is Increases👪, Click for details.
Prebiotics and similar Human milk oligosaccharides (prebiotic, Holigos, Stachyose) 2 Studies recorded. The consensus is Decreases👪, Click for details.
Prebiotics and similar inulin (prebiotic) 4 Studies recorded. The consensus is Increases👪, Click for details.
Prebiotics and similar oligofructose-enriched inulin (prebiotic) 1 Studies recorded. The consensus is Increases👪, Click for details.
Prebiotics and similar resistant starch 1 Studies recorded. The consensus is Decreases👪, Click for details.
Prebiotics and similar xylooligosaccharide (prebiotic) 1 Studies recorded. The consensus is Increases👪, Click for details.
Prescription - Other amlodipine,(prescription) 1 Studies recorded. The consensus is Increases👪, Click for details.
Prescription - Other epicor 1 Studies recorded. The consensus is Increases👪, Click for details.
Prescription - Other estradiol valerate,(prescription) 1 Studies recorded. The consensus is Increases👪, Click for details.
Prescription - Other ethinylestradiol,(prescription) 1 Studies recorded. The consensus is Increases👪, Click for details.
Prescription - Other heparin 1 Studies recorded. The consensus is Decreases👪, Click for details.
Prescription - Other metformin (prescription) 7 Studies recorded. The consensus is Increases👪, Click for details.
Prescription - Other Morphine 1 Studies recorded. The consensus is Decreases👪, Click for details.
Probiotics Akkermansia muciniphila (probiotic) 3 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics Bacillus clausii (Probiotics) 1 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics bacillus coagulans (probiotics) 2 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics bacillus licheniformis,(probiotics) 2 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics bacillus subtilis (probiotics) 2 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics bifidobacterium animalis lactis (probiotics) 3 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics bifidobacterium lactis bb12 (probiotics) 1 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics bifidobacterium lactis,streptococcus thermophilus probiotic 1 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics bifidobacterium longum (probiotics) 1 Studies recorded. The consensus is Decreases👪, Click for details.
Probiotics bifidobacterium longum bb536 (probiotics) 1 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics enterococcus faecium (probiotic) 1 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics lactobacillus kefiri (NOT KEFIR) 1 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics lactobacillus plantarum (probiotics) 5 Studies recorded. The consensus is Decreases👶👪, Click for details.
Probiotics lactobacillus reuteri (probiotics) 1 Studies recorded. The consensus is Decreases👪, Click for details.
Probiotics lactobacillus rhamnosus (probiotics) 2 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics lactobacillus rhamnosus gg (probiotics) 1 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics lactobacillus rhamnosus gg,lactobacillus,rhamnosus,propionibacterium freudenreichii,bifidobacterium breve (probiotics) 1 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics Limosilactobacillus fermentum (probiotic) 3 Studies recorded. The consensus is Increases👪, Click for details.
Sugar and similar chitosan,(sugar) 2 Studies recorded. The consensus is Increases👪, Click for details.
Sugar and similar lactulose 1 Studies recorded. The consensus is Increases👪, Click for details.
Sugar and similar polydextrose 1 Studies recorded. The consensus is Increases👪, Click for details.
Sugar and similar stevia 1 Studies recorded. The consensus is Increases👪, Click for details.
Vitamins, Minerals and similar chlorine 1 Studies recorded. The consensus is Increases👪, Click for details.
Vitamins, Minerals and similar Ferric citrate 1 Studies recorded. The consensus is Increases👪, Click for details.
Vitamins, Minerals and similar magnesium 1 Studies recorded. The consensus is Increases👪, Click for details.
Vitamins, Minerals and similar vitamin a 2 Studies recorded. The consensus is Increases👪, Click for details.
Vitamins, Minerals and similar vitamin d 2 Studies recorded. The consensus is Increases👪, Click for details.

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