Filifactor Details: NCBI 44259, gram-negative or unknown [genus]

| Filifactor| Filifactor Collins et al. 1994

  1. Oral health: Filifactor species are part of the normal oral microbiota, where they contribute to the formation of dental plaque and biofilms. While they are generally considered commensal bacteria, Filifactor species have been associated with periodontal diseases such as gingivitis and periodontitis. These bacteria can proliferate in the gingival sulcus and periodontal pockets, where they contribute to inflammation, tissue destruction, and bone loss characteristic of periodontal diseases.

  2. Respiratory infections: Filifactor species have been detected in the respiratory tract and have been associated with respiratory infections such as pneumonia and chronic obstructive pulmonary disease (COPD). While their exact role in respiratory infections is not fully understood, Filifactor species may contribute to airway inflammation, mucus production, and exacerbations of respiratory conditions. Further research is needed to elucidate the mechanisms by which Filifactor species interact with the respiratory mucosa and contribute to respiratory infections.

  3. Systemic diseases: There is growing evidence linking oral bacteria, including Filifactor species, to systemic diseases such as cardiovascular disease, diabetes, and rheumatoid arthritis. Oral bacteria can enter the bloodstream through oral mucosal lesions, dental procedures, or periodontal pockets, leading to bacteremia and systemic dissemination. Once in the bloodstream, these bacteria may contribute to systemic inflammation, endothelial dysfunction, and the progression of systemic diseases. While the exact role of Filifactor species in systemic diseases requires further investigation, their presence in the oral cavity may have implications for systemic health.

  4. Antibiotic resistance: Some species within the genus Filifactor have been reported to exhibit antibiotic resistance, which may complicate treatment of infections caused by these bacteria. Antibiotic-resistant strains of Filifactor species have been isolated from dental plaque and periodontal pockets, highlighting the importance of antimicrobial stewardship and surveillance of antibiotic resistance in oral bacteria.

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Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Filifactor

Using Kaltoft-Moldrup Heuristic Using uploaded data for Filifactor

Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)
LabKM LowKM Percentile LowKM HighKM Percentile HighLab LowLab HighMean MedianStandard DeviationBox Plot LowBox Plot High
* 4 0 %ile 669 100 %ile 0 410 149 119 133.1 41 239
biomesight 10 0 %ile 110 89.6 %ile 0 7155 276.3 40 3509.6 0 120
thorne 3 0 %ile 67 100 %ile 0 54 21.5 16 16.4 4 34
thryve 1 0 %ile 89 90.7 %ile 0 454 69.9 31 196 9 103
Lab Suggestions for Filifactor
Filifactor (NCBI 44259) per million
Low Boundary High Boundary Low Boundary %age High Boundary %age Lab Samples
4.15 11.67 0.0004 0.0012 Thorne (20/80%ile)
Statistic by Lab Source for Filifactor
These desired values are reported from the lab reports
Lab Frequency Seen Average Standard Deviation Sample Count Lab Samples
BiomeSight 30.601 %   0.025 %  0.31 % 870.0 2843
BiomeSightRdp 3.125 %   0.001 %  % 1.0 32
CerbaLab 66.667 %   0.007 %  0.008 % 2.0 3
custom 15.254 %   0.007 %  0.003 % 9.0 59
es-xenogene 41.379 %   0.007 %  0.003 % 12.0 29
SequentiaBiotech 50 %   0.022 %  0.014 % 18.0 36
Thorne 82.353 %   0.001 %  0.001 % 70.0 85
Thryve 32.101 %   0.007 %  0.018 % 443.0 1380

Symptoms Associated with Filifactor From Citizen Science Studies

Click on Impact for information if high or low levels are causing the impact

MagnitudeImpactSymptom
1 Reduces Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep)
1 Reduces General: Myalgia (pain)
1 Reduces General: Headaches
1 Reduces Neurological: Confusion
1 Reduces Neurological: Short-term memory issues
1 Reduces Neurological: Disorientation
1 Reduces Neurological-Vision: inability to focus eye/vision
1 Reduces Neurological-Audio: hypersensitivity to noise
1 Reduces Neurological: emotional overload
1 Increases Autonomic Manifestations: Postural orthostatic tachycardia syndrome (POTS)
1 Increases Autonomic Manifestations: nausea
1 Reduces Autonomic Manifestations: irritable bowel syndrome
1 Increases Autonomic Manifestations: bladder dysfunction
1 Increases Autonomic Manifestations: palpitations
1 Reduces Autonomic Manifestations: exertional dyspnea
1 Reduces Neuroendocrine Manifestations: sweating episodes
1 Reduces Neuroendocrine Manifestations: cold extremities
1 Reduces Neuroendocrine Manifestations: intolerance of extremes of heat and cold
1 Increases Neuroendocrine Manifestations: marked weight change
1 Increases Neuroendocrine Manifestations: abnormal appetite
1 Reduces Neuroendocrine Manifestations: loss of adaptability
1 Reduces Neuroendocrine Manifestations: worsening of symptoms with stress.
1 Increases Immune Manifestations: tender lymph nodes
1 Increases Immune Manifestations: recurrent flu-like symptoms
1 Reduces Immune Manifestations: general malaise
1 Increases Immune Manifestations: medication sensitivities.
1 Reduces Onset: Sudden
1 Reduces Infection: Lyme
1 Reduces Infection: Mycoplasma
1 Reduces Comorbid: Multiple Chemical Sensitivity
1 Reduces Comorbid: Fibromyalgia
1 Reduces Neurological: Neuropathy
1 Increases Neurological: Myoclonic jerks or seizures
1 Reduces Neuroendocrine Manifestations: Excessive adrenaline
1 Reduces Neurological: Cognitive/Sensory Overload
1 Increases Neurological: Slowed speech
1 Reduces Neurological-Sleep: Insomnia
1 Reduces Neurological-Sleep: Vivid Dreams/Nightmares
1 Reduces Immune Manifestations: Bloating
1 Reduces Immune Manifestations: Abdominal Pain
1 Reduces Immune Manifestations: Diarrhea
1 Reduces Neuroendocrine Manifestations: Air Hunger
1 Reduces Onset: less than 04 years since onset
1 Reduces Onset: less than 16 years since onset
1 Reduces Onset: less than 32 years since onset
1 Reduces Immune Manifestations: Alcohol Intolerant
1 Reduces Neurological-Sleep: Sleep Apnea
1 Increases Neurological: High degree of Empathy before onset
1 Reduces Neurological: Seasonal Affective Disorder (SAD)
1 Reduces Neuroendocrine Manifestations: Dry Eye (Sicca or Sjogren Syndrome)
1 Reduces Comorbid-Mouth: Dry Mouth
1 Reduces Infection: Parasite - Other
1 Reduces Comorbid: Mold Sensitivity / Exposure
1 Reduces Neurological-Vision: Blurred Vision
1 Reduces Virus: Human Herpesvirus 6 positive (HHV6)
1 Increases Immune Manifestations: Hair loss
1 Reduces Immune Manifestations: Thick blood / Hypercoagulation
1 Reduces Neurological-Sleep: Inability for deep (delta) sleep
1 Reduces Comorbid-Mouth: Gingivits / Gum Disease
1 Reduces Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndrome
1 Reduces Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grinding
1 Increases Autonomic Manifestations: Cortisol disorders or irregularity
1 Reduces Comorbid: Small intestinal bacterial overgrowth (SIBO)
1 Reduces Comorbid: Inflammatory bowel disease
1 Reduces Comorbid: Restless Leg
1 Reduces Asymptomatic: No Health Issues
1 Reduces Comorbid: Histamine or Mast Cell issues
1 Reduces Neurological: Executive Decision Making (Difficulty making)
1 Increases Gender: Male
1 Reduces Gender: Female
1 Increases Onset: 2010-2020
1 Reduces Onset: 2000-2010
1 Reduces Age: 0-10
1 Increases Age: 10-20
1 Reduces Age: 30-40
1 Reduces Sleep: Need to nap daily
1 Reduces Sleep: Problems falling asleep
1 Reduces Sleep: Problems staying asleep
1 Reduces Sleep: Waking up early in the morning (e.g. 3 AM)
1 Reduces Sleep: Daytime drowsiness
1 Reduces Pain: Joint pain
1 Reduces Pain: Eye pain
1 Reduces Pain: Aching of the eyes or behind the eyes
1 Reduces Pain: Sensitivity to pain
1 Reduces Pain: Myofascial pain
1 Reduces Neuroendocrine: Cold limbs (e.g. arms, legs hands)
1 Reduces Neuroendocrine: Feeling hot or cold for no reason
1 Reduces Neuroendocrine: Feeling like you have a high temperature
1 Reduces Neuroendocrine: Alcohol intolerance
1 Reduces Neuroendocrine: Temperature fluctuations throughout the day
1 Reduces Immune: Tender / sore lymph nodes
1 Reduces Immune: Sensitivity to smell/food/medication/chemicals
1 Reduces Immune: Viral infections with prolonged recovery periods
1 Reduces Other: Sensitivity to mold
1 Reduces Other: Sensitivity to vibrations
1 Reduces Neurocognitive: Difficulty expressing thoughts
1 Reduces Neurocognitive: Can only focus on one thing at a time
1 Reduces Neurocognitive: Unable to focus vision and/or attention
1 Reduces Neurocognitive: Feeling disoriented
1 Reduces Post-exertional malaise: Post-exertional malaise
1 Reduces Post-exertional malaise: Next-day soreness after everyday activities
1 Reduces Post-exertional malaise: Mentally tired after the slightest effort
1 Reduces Post-exertional malaise: Physically tired after minimum exercise
1 Reduces Post-exertional malaise: Physically drained or sick after mild activity
1 Reduces Post-exertional malaise: Worsening of symptoms after mild physical activity
1 Reduces Post-exertional malaise: Worsening of symptoms after mild mental activity
1 Reduces Official Diagnosis: Autism
1 Reduces Official Diagnosis: Chronic Fatigue Syndrome (CFS/ME)
1 Reduces Official Diagnosis: Irritable Bowel Syndrome
1 Reduces Joint: Stiffness and swelling
1 Reduces Joint: Tenderness
1 Reduces Immune Manifestations: Mucus in the stool
1 Reduces Comorbid-Mouth: Mouth Sores
1 Reduces Immune Manifestations: Inflammation of skin, eyes or joints
1 Reduces Neurocognitive: Brain Fog
1 Increases Neuroendocrine Manifestations: Painful menstrual periods
1 Reduces Official Diagnosis: Fibromyalgia
1 Reduces Comorbid-Mouth: Ulcers (mouth)
1 Reduces Immune Manifestations: Inflammation (General)
1 Reduces Comorbid: Carbohydrate intolerance
1 Reduces Comorbid: Methylation issues (MTHFR)
1 Reduces Immune: Chronic Sinusitis
1 Increases Autonomic: Ocassional Tachycardia (Rapid heart beat)
1 Reduces Blood Type: O Positive
1 Increases Blood Type: A Positive
1 Reduces Comorbid: Salicylate sensitive
1 Reduces Comorbid: High Anxiety
1 Reduces Comorbid: Sugars cause sleep or cognitive issues
1 Reduces Comorbid: Mood Swings
1 Reduces Comorbid: Constipation and Explosions (not diarrohea)
1 Reduces Comorbid: Constipation and Diarrohea (not explosions)
1 Reduces Official Diagnosis: Allergic Rhinitis (Hay Fever)
1 Reduces Comorbid: Snoring (NOT Sleep Apnea
1 Reduces Comorbid: Sleep Apnea Diagnosis
1 Reduces Official Diagnosis: Gastroesophageal reflux disease (GERD)
1 Reduces Comorbid: Panic Attacks
1 Increases DePaul University Fatigue Questionnaire : Racing heart
1 Reduces DePaul University Fatigue Questionnaire : Shortness of breath
1 Reduces DePaul University Fatigue Questionnaire : Night sweats
1 Increases DePaul University Fatigue Questionnaire : Chilled or shivery
1 Reduces DePaul University Fatigue Questionnaire : Hot or Cold spells
1 Reduces DePaul University Fatigue Questionnaire : Feeling like you have a temperature
1 Increases DePaul University Fatigue Questionnaire : Temperature lower than normal
1 Increases DePaul University Fatigue Questionnaire : Tingling feeling
1 Increases DePaul University Fatigue Questionnaire : Blurred Vision
1 Increases DePaul University Fatigue Questionnaire : Eye pain
1 Increases DePaul University Fatigue Questionnaire : Rash
1 Reduces DePaul University Fatigue Questionnaire : Feel unsteady on feet
1 Reduces DePaul University Fatigue Questionnaire : Need to nap during each day
1 Reduces DePaul University Fatigue Questionnaire : Difficulty staying asleep
1 Reduces DePaul University Fatigue Questionnaire : Absent-mindedness
1 Reduces DePaul University Fatigue Questionnaire : Confusion/disorientation
1 Reduces DePaul University Fatigue Questionnaire : Difficulty reasoning things out
1 Reduces DePaul University Fatigue Questionnaire : Difficulty following things
1 Reduces DePaul University Fatigue Questionnaire : Frequently loose train of thought
1 Reduces DePaul University Fatigue Questionnaire : Difficulty retaining information
1 Reduces DePaul University Fatigue Questionnaire : Difficulty recalling information
1 Reduces DePaul University Fatigue Questionnaire : Frequently get words or numbers in the wrong order
1 Reduces DePaul University Fatigue Questionnaire : Slow to react
1 Reduces DePaul University Fatigue Questionnaire : New trouble with math
1 Increases DePaul University Fatigue Questionnaire : Concern with driving
1 Reduces DePaul University Fatigue Questionnaire : Anxiety/tension
1 Reduces DePaul University Fatigue Questionnaire : Easily irritated
1 Reduces DePaul University Fatigue Questionnaire : Depression
1 Reduces DePaul University Fatigue Questionnaire : Mood swings
1 Reduces DePaul University Fatigue Questionnaire : Does physical activity make you feel worse
1 Reduces DePaul University Fatigue Questionnaire : Fatigue
1 Increases DePaul University Fatigue Questionnaire : Sore Throat
1 Reduces DePaul University Fatigue Questionnaire : Muscle Pain (i.e., sensations of pain or aching in your muscles. This does not include weakness or pain in other areas such as joints)
1 Increases DePaul University Fatigue Questionnaire : Pain in Multiple Joints without Swelling or Redness
1 Increases DePaul University Fatigue Questionnaire : Nausea
1 Reduces DePaul University Fatigue Questionnaire : Sensitivity to Alcohol
1 Reduces DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired
1 Reduces DePaul University Fatigue Questionnaire : Post-exertional malaise, feeling worse after doing activities that require either physical or mental exertion
1 Reduces Condition: Post-Traumatic Stress Disorder
1 Reduces Condition: Acne
1 Reduces Condition: Generalized anxiety disorder
1 Reduces Condition: Non-Celiac Gluten Sensitivity
1 Reduces Condition: ME/CFS with IBS
1 Reduces Condition: ME/CFS without IBS
1 Reduces Physical: Tonsils removed
1 Reduces Physical: Amalgam fillings
1 Reduces Physical: Eastern European
1 Reduces Physical: Breastfed
1 Reduces Physical: Pets
1 Increases Physical: Good Air Quality
1 Reduces Physical: Work-Sitting
1 Increases Physical: Steps Per Day 2000-4000
1 Reduces Physical: Steps Per Day 4000-8000
1 Reduces Physical: Steps Per Day 8000-16000
1 Reduces Neuroendocrine Manifestations: Poor gut motility
1 Reduces Autism: High Functioning
1 Reduces Official Diagnosis: Hypercholesterolemia (High Cholesterol)
1 Increases Official Diagnosis: COVID19 (Long Hauler)
1 Reduces Immune Manifestations: Chronic Flatus / Flatulence / gas
1 Reduces Neurocognitive: Aphantasia ( inability to visualize mental images)
1 Increases Official Diagnosis: COVID19 (Fully Recovered)
1 Increases General: Anhedonia (inability to feel pleasure)

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Foods Containing the Filifactor bacteria

Data comes from FoodMicrobionet. For the meaning of weight, see that site. The bacteria does not need to be alive to have an effect.

Passito wine Weight: 0.0645 Tej, Ethiopia Weight: 0.0294 Palm wine Weight: 0.003876

I would like to know what can change the quality that I have

Data Contradictions β€” Limits of Certainity

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General Substance Specific Substance Effect
Amino Acid and similar l-proline 1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc doxycycline (antibiotic)s[CFS] 1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc metronidazole (antibiotic)s[CFS] 1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc minocycline (antibiotic)s[CFS] 1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc Rapamycin 1 Studies recorded. The consensus is Decreases📓, Click for details.
Common Supplements Tributyrin 1 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style high sugar diet 1 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style high-fat diets 1 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style Olive Oil 1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings) Cranberry 1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings) cranberry bean flour 2 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings) ku ding cha tea 1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings) Nicotine, Nicotine Patch 1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings) plantain bananas 1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings) rare meat 1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings) safflower oil 1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings) tea 1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice berberine 1 Studies recorded. The consensus is Increases📓, Click for details.
Herb or Spice Carthamus tinctorius L,Safflower 1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice oregano (origanum vulgare, oil) | 1 Studies recorded. The consensus is Increases📓, Click for details.
Miscellaneous, food additives, and other odd items bile (acid/salts) 2 Studies recorded. The consensus is Decreases📓, Click for details.
Miscellaneous, food additives, and other odd items Bismuth Salts 2 Studies recorded. The consensus is Decreases📓, Click for details.
Miscellaneous, food additives, and other odd items Polyethylene glycol 1 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar fructo-oligosaccharides (prebiotic) 1 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar resistant starch 1 Studies recorded. The consensus is Decreases📓, Click for details.
Prescription - Other metformin (prescription) 1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics bifidobacterium longum,lactobacillus helveticus (probiotics) 1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics lactobacillus reuteri (probiotics) 1 Studies recorded. The consensus is Decreases📓, Click for details.
Sugar and similar d-trehalose (sugar) 1 Studies recorded. The consensus is Increases📓, Click for details.
Sugar and similar glucose (sugar) 1 Studies recorded. The consensus is Increases📓, Click for details.
Sugar and similar saccharin 1 Studies recorded. The consensus is Increases📓, Click for details.

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