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🍽️ doxylamine succinate,(prescription) [Can cause cognitive issues]

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  1. Sleep Aid: Doxylamine succinate is primarily used to promote sleep and relieve occasional insomnia. It works by blocking the action of histamine, a neurotransmitter involved in wakefulness, thereby inducing drowsiness and facilitating sleep initiation.

  2. Allergy Relief: It may be used to alleviate symptoms of allergic rhinitis, hay fever, and other allergic reactions, such as sneezing, itching, watery eyes, and runny nose, by blocking the effects of histamine.

  3. Nausea and Vomiting: Doxylamine succinate is sometimes used to relieve nausea and vomiting associated with motion sickness or morning sickness during pregnancy. It exerts antiemetic effects by acting on the vomiting center in the brain.

  4. Cough and Cold: It may be included in over-the-counter cold and cough medications to help relieve symptoms such as nasal congestion, coughing, and sneezing, as well as to promote sleep in individuals with cold or flu symptoms.

  5. Motion Sickness: Doxylamine succinate may be used to prevent and alleviate symptoms of motion sickness, such as nausea and vomiting, by exerting its sedative and antiemetic effects.

  6. Morning Sickness: In pregnant women experiencing morning sickness, doxylamine succinate, often combined with pyridoxine (vitamin B6), is sometimes used to alleviate nausea and vomiting during pregnancy.

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Data Contradictions β€” Limits of Certainity

Impacted of doxylamine succinate,(prescription) [Can cause cognitive issues] On Probiotics

Rank Probiotic Impact
species Akkermansia muciniphila Reduces
species Bifidobacterium adolescentis Reduces
species Bifidobacterium longum Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by doxylamine succinate,(prescription) [Can cause cognitive issues]

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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Taxonomy Rank Effect Citations Notation
Agathobacter genus Decreases 👪 Source Study
Bifidobacterium genus Decreases 👪 Source Study
Mediterraneibacter genus Decreases 👪 Source Study
Dorea genus Decreases 👪 Source Study
Collinsella genus Decreases 👪 Source Study proinflammatory
Bacteroides genus Decreases 👪 Source Study
Enterocloster genus Decreases 👪 Source Study
Blautia genus Decreases 👪 Source Study
Odoribacter genus Decreases 👪 Source Study
Eggerthella genus Decreases 👪 Source Study
Roseburia genus Decreases 👪 Source Study
Veillonella genus Decreases 👪 Source Study
Bilophila genus Decreases 👪 Source Study High Level Cause Brain Fog(Cognitive impairment)
Coprococcus genus Decreases 👪 Source Study
Akkermansia genus Decreases 👪 Source Study
Streptococcus genus Decreases 👪 Source Study
Parabacteroides genus Decreases 👪 Source Study BMI, fat percent,blood pressure
Phocaeicola genus Decreases 👪 Source Study
Clostridioides genus Decreases 👪 Source Study
unclassified Robinsoniella no rank Decreases ⚗️ Source Study
unclassified Fusobacterium no rank Decreases ⚗️ Source Study
unclassified Negativicoccus no rank Decreases ⚗️ Source Study
Eggerthellales order Decreases ⚗️ Source Study
Bifidobacterium longum species Decreases 📓 Source Study
[Ruminococcus] torques species Decreases 📓 Source Study
Agathobacter rectalis species Decreases 📓 Source Study
Bacteroides caccae species Decreases 📓 Source Study
Dorea formicigenerans species Decreases 📓 Source Study
Bifidobacterium adolescentis species Decreases 📓 Source Study
Collinsella aerofaciens species Decreases 📓 Source Study
Bacteroides xylanisolvens species Decreases 📓 Source Study
Enterocloster bolteae species Decreases 📓 Source Study
Blautia obeum species Decreases 📓 Source Study
Odoribacter splanchnicus species Decreases 📓 Source Study
Eggerthella lenta species Decreases 📓 Source Study
[Ruminococcus] gnavus species Decreases 📓 Source Study
Anaerofustis stercorihominis species Decreases ⚗️ Source Study
Asaccharospora irregularis species Decreases ⚗️ Source Study
Roseburia hominis species Decreases 📓 Source Study
Veillonella parvula species Decreases 📓 Source Study
Bilophila wadsworthia species Decreases 📓 Source Study
Negativicoccus sp. S5-A15 species Decreases ⚗️ Source Study
Paraprevotella clara species Decreases ⚗️ Source Study
Slackia sp. NATTS species Decreases ⚗️ Source Study
Bacteroides ovatus species Decreases 📓 Source Study
Pseudoflavonifractor capillosus species Decreases ⚗️ Source Study
[Collinsella] massiliensis species Decreases ⚗️ Source Study
Parvibacter caecicola species Decreases ⚗️ Source Study
Coprococcus comes species Decreases 📓 Source Study
Akkermansia muciniphila species Decreases 📓 Source Study
Streptococcus parasanguinis species Decreases 📓 Source Study
Parabacteroides merdae species Decreases 📓 Source Study Infectious bacteria
Phocaeicola vulgatus species Decreases 📓 Source Study
Clostridioides difficile species Decreases 📓 Source Study Colitis
Coriobacterineae suborder Decreases ⚗️ Source Study
Bifidobacterium longum subsp. infantis subspecies Decreases 👶 Source Study
Bifidobacterium longum subsp. longum subspecies Decreases 👶 Source Study
Bifidobacterium longum subsp. suillum subspecies Decreases 👶 Source Study
Chlamydiae/Verrucomicrobia group superphylum Decreases ⚗️ Source Study

Impact of doxylamine succinate,(prescription) [Can cause cognitive issues] on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.1 0.1
Acne 0.3 -0.3
ADHD 2 0.2 9
Age-Related Macular Degeneration and Glaucoma 0.3 0 0
Allergic Rhinitis (Hay Fever) 0.4 1.3 -2.25
Allergies 1.9 0.5 2.8
Allergy to milk products 0.1 0.3 -2
Alopecia (Hair Loss) 0.5 0.5
Alzheimer's disease 0.9 2.6 -1.89
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0.8 0.1 7
Ankylosing spondylitis 0.9 0.4 1.25
Anorexia Nervosa 0 0.6 0
Antiphospholipid syndrome (APS) 0 0.1 0
Asthma 0.5 0.4 0.25
Atherosclerosis 0.4 0.4 0
Atrial fibrillation 1.2 0.5 1.4
Autism 2.9 3 -0.03
Barrett esophagus cancer 0.1 0 0
Bipolar Disorder 0.3 0.4 -0.33
Brain Trauma 0.4 0.2 1
Carcinoma 1.3 1.1 0.18
Celiac Disease 0.4 1.8 -3.5
Cerebral Palsy 0.5 0.4 0.25
Chronic Fatigue Syndrome 1.7 1.9 -0.12
Chronic Kidney Disease 1.2 0.9 0.33
Chronic Lyme 0.2 -0.2
Chronic Obstructive Pulmonary Disease (COPD) 0.2 0.1 1
Chronic Urticaria (Hives) 0.1 0.1 0
Coagulation / Micro clot triggering bacteria 0.1 0.3 -2
Colorectal Cancer 0.7 0.7 0
Constipation 0.2 0.2 0
Coronary artery disease 0.7 0.3 1.33
COVID-19 3.6 4.1 -0.14
Crohn's Disease 1.8 1.8 0
cystic fibrosis 0.5 -0.5
deep vein thrombosis 0.1 -0.1
Depression 3.5 3.2 0.09
Dermatomyositis 0 0.3 0
Eczema 0.3 0.3 0
Endometriosis 0.9 0.2 3.5
Eosinophilic Esophagitis 0.1 -0.1
Epilepsy 0.8 0.8 0
Fibromyalgia 0.5 0.5 0
Functional constipation / chronic idiopathic constipation 1.3 1.6 -0.23
gallstone disease (gsd) 0.5 0.4 0.25
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.1 0.3 -2
Generalized anxiety disorder 0.4 1.2 -2
Glioblastoma 0 0
Gout 0.1 -0.1
Graves' disease 0.6 0.6 0
Halitosis 0.2 0 0
Hashimoto's thyroiditis 1.6 0.5 2.2
Hidradenitis Suppurativa 0.1 0.1 0
Histamine Issues,Mast Cell Issue, DAO Insufficiency 1.6 0.6 1.67
hypercholesterolemia (High Cholesterol) 0.1 0.1 0
hyperglycemia 0.7 -0.7
Hyperlipidemia (High Blood Fats) 0.5 0.2 1.5
hypersomnia 0.2 -0.2
hypertension (High Blood Pressure 0.7 2 -1.86
Hypothyroidism 0.6 -0.6
Hypoxia 0.2 0.2
IgA nephropathy (IgAN) 0.6 -0.6
Inflammatory Bowel Disease 1 2.7 -1.7
Insomnia 0.3 0.2 0.5
Intelligence 0.1 0.1
Intracranial aneurysms 0.3 0.2 0.5
Irritable Bowel Syndrome 1.1 0.9 0.22
Liver Cirrhosis 1.3 1 0.3
Long COVID 2.5 3.3 -0.32
Low bone mineral density 0.1 -0.1
Lung Cancer 0.4 0.5 -0.25
ME/CFS with IBS 0.3 1.2 -3
ME/CFS without IBS 0.8 1 -0.25
Menopause 1.2 1.2
Metabolic Syndrome 2.5 2.9 -0.16
Mood Disorders 4.1 3.3 0.24
multiple chemical sensitivity [MCS] 0.2 0.1 1
Multiple Sclerosis 2.1 0.8 1.63
Multiple system atrophy (MSA) 0.5 0.4 0.25
Neuropathy (all types) 0.2 0.2
neuropsychiatric disorders (PANDAS, PANS) 0.1 0.1
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 0.6 2.7 -3.5
NonCeliac Gluten Sensitivity 0.3 -0.3
Obesity 3.8 1.3 1.92
obsessive-compulsive disorder 0.8 2.2 -1.75
Osteoarthritis 0.4 0.4
Osteoporosis 0.4 0.4 0
pancreatic cancer 0.2 0.2
Parkinson's Disease 0.9 0.7 0.29
Polycystic ovary syndrome 0.3 0.5 -0.67
Postural orthostatic tachycardia syndrome 0.3 -0.3
Premenstrual dysphoric disorder 0.6 0 0
primary biliary cholangitis 0.2 0.2 0
Psoriasis 1.4 0.4 2.5
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 2 1.2 0.67
Rosacea 0.9 0.1 8
Schizophrenia 2.4 0.6 3
scoliosis 0.1 0.1 0
Sjögren syndrome 0.6 1.4 -1.33
Sleep Apnea 0.5 0.6 -0.2
Small Intestinal Bacterial Overgrowth (SIBO) 0 0.7 0
Stress / posttraumatic stress disorder 0.8 1.1 -0.38
Systemic Lupus Erythematosus 1.1 0.6 0.83
Tic Disorder 0.2 0.6 -2
Tourette syndrome 0.1 0.1 0
Type 1 Diabetes 0.7 0.6 0.17
Type 2 Diabetes 2.5 1.4 0.79
Ulcerative colitis 0.8 1.1 -0.38
Unhealthy Ageing 1.8 1.1 0.64

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