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Digestive Health: MCC is not digested or absorbed in the human digestive tract and passes through the gastrointestinal system largely unchanged. As a result, it can contribute to regular bowel movements and may help alleviate symptoms of constipation by adding bulk to stool. However, it does not directly influence gut microbiota composition or fermentation processes like prebiotic fibers.
Weight Management: MCC is often used as a filler in weight management supplements or medications. While it does not have direct effects on weight loss or metabolism, it can contribute to the volume of a supplement or medication, potentially promoting feelings of fullness and reducing appetite when consumed with sufficient water.
Blood Glucose Regulation: Since MCC is not metabolized in the body, it does not directly impact blood glucose levels or insulin sensitivity. However, it may be used as an inert carrier in pharmaceutical formulations designed to control the release of active ingredients, including those used to manage blood sugar levels in diabetes.
Cholesterol Reduction: MCC itself does not have cholesterol-lowering properties. However, it may be used in formulations of medications or dietary supplements intended to support cardiovascular health, where other active ingredients may target cholesterol reduction.
Gastrointestinal Disorders: In some cases, individuals with certain gastrointestinal disorders, such as Crohn's disease or ulcerative colitis, may have difficulty tolerating MCC due to its bulking effects. In these cases, consumption of MCC-containing supplements or medications may exacerbate symptoms such as bloating or abdominal discomfort.
Safety Considerations: MCC is generally regarded as safe for consumption and is widely used in pharmaceuticals and dietary supplements. However, individuals with known sensitivities or allergies to cellulose derivatives should exercise caution when using products containing MCC. Additionally, excessive consumption of MCC without adequate fluid intake may lead to gastrointestinal issues such as obstruction or constipation.
| Rank | Probiotic | Impact |
|---|
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Allergies | 0.5 | 0.5 | |
| Alopecia (Hair Loss) | 0.4 | 0.4 | |
| Alzheimer's disease | 0.5 | 0.5 | 0 |
| Ankylosing spondylitis | 0.2 | 0.2 | |
| Atherosclerosis | 0.2 | 0.2 | |
| Atrial fibrillation | 0.2 | 0.2 | |
| Autism | 0.2 | 0.2 | |
| Barrett esophagus cancer | 0.5 | 0.5 | |
| Brain Trauma | 0.2 | 0.2 | |
| Breast Cancer | 0.3 | -0.3 | |
| Carcinoma | 0.7 | 0.7 | 0 |
| Celiac Disease | 0.2 | -0.2 | |
| Chronic Kidney Disease | 0.2 | -0.2 | |
| Colorectal Cancer | 0.2 | -0.2 | |
| Constipation | 0.3 | -0.3 | |
| Coronary artery disease | 0.2 | 0.2 | |
| COVID-19 | 0.8 | -0.8 | |
| Crohn's Disease | 0.7 | 0.2 | 2.5 |
| Depression | 0.3 | 0.2 | 0.5 |
| Endometriosis | 0.5 | 0.5 | |
| Epilepsy | 0.2 | 0.2 | |
| erectile dysfunction | 0.2 | 0.2 | |
| Functional constipation / chronic idiopathic constipation | 0.3 | -0.3 | |
| Graves' disease | 0.9 | 0.2 | 3.5 |
| hypercholesterolemia (High Cholesterol) | 0.5 | 0.5 | |
| hyperglycemia | 0.5 | 0.5 | |
| Hyperlipidemia (High Blood Fats) | 0.2 | 0.2 | 0 |
| hypersomnia | 0.3 | -0.3 | |
| hypertension (High Blood Pressure | 0.7 | 0.7 | |
| Inflammatory Bowel Disease | 0.2 | 0.2 | 0 |
| Intelligence | 0.5 | -0.5 | |
| Intracranial aneurysms | 0.2 | -0.2 | |
| Liver Cirrhosis | 0.5 | 0.5 | |
| Long COVID | 1.7 | 1.2 | 0.42 |
| Metabolic Syndrome | 1.2 | 1.2 | |
| Mood Disorders | 0.4 | 0.7 | -0.75 |
| Multiple Sclerosis | 0.5 | -0.5 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 0.2 | 0.2 | |
| Obesity | 1.2 | 0.2 | 5 |
| pancreatic cancer | 0.2 | -0.2 | |
| Parkinson's Disease | 0.7 | 0.7 | |
| Premenstrual dysphoric disorder | 0.2 | 0.2 | |
| primary biliary cholangitis | 0.3 | 0.2 | 0.5 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 0.2 | 0.2 | 0 |
| Schizophrenia | 0.2 | 0.5 | -1.5 |
| Stress / posttraumatic stress disorder | 0.5 | 0.8 | -0.6 |
| Tic Disorder | 0.2 | -0.2 | |
| Type 2 Diabetes | 1.2 | 1.2 | |
| Ulcerative colitis | 0.3 | 0.7 | -1.33 |
| Unhealthy Ageing | 0.5 | -0.5 |
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