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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomImpactPredictor of Bacteria Shift
Age: 30-40Worsen1.92
Age: 40-50Worsen2.43
Age: 60-70Improves-2.09
Asymptomatic: Live in house with person with probable microbiome dysfunctionImproves-2.86
Asymptomatic: Minor Health Issues (a few symptoms only)Worsen2.95
Asymptomatic: No Health IssuesWorsen0.94
Autism: Official DiagnosisWorsen0.97
Autonomic Manifestations: cardiac arrhythmiasImproves-1.18
Autonomic Manifestations: Cortisol disorders or irregularity Worsen1.69
Autonomic Manifestations: irritable bowel syndromeWorsen1.21
Autonomic Manifestations: Orthostatic intoleranceImproves-3.45
Autonomic Manifestations: urinary frequency dysfunctionImproves-1.78
Autonomic: Inability to tolerate an upright positionImproves-2.81
Autonomic: Irregular heartbeatsWorsen1.21
Blood Type: A PositiveImproves-3.37
Blood Type: O PositiveWorsen0.09
Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grindingImproves-2.5
Comorbid-Mouth: Dry MouthImproves-1.37
Comorbid-Mouth: Mouth SoresWorsen1.92
Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndromeImproves-2.54
Comorbid: Constipation and Explosions (not diarrohea)Worsen1.87
Comorbid: FibromyalgiaImproves-2.82
Comorbid: High AnxietyWorsen0.45
Comorbid: Histamine or Mast Cell issuesImproves-2.5
Comorbid: HypothyroidismImproves-2.81
Comorbid: Inflammatory bowel disease Improves-3.04
Comorbid: Methylation issues (MTHFR)Improves-2.83
Comorbid: MigraineImproves-2.92
Comorbid: Small intestinal bacterial overgrowth (SIBO)Worsen1.21
Comorbid: Snoring (NOT Sleep ApneaWorsen2.78
Condition: ME/CFS with IBSImproves-1.8
DePaul University Fatigue Questionnaire : Abdomen painImproves-1.02
DePaul University Fatigue Questionnaire : AllergiesImproves-3.24
DePaul University Fatigue Questionnaire : Anxiety/tensionImproves-3.07
DePaul University Fatigue Questionnaire : DepressionWorsen1.24
DePaul University Fatigue Questionnaire : Difficulty falling asleepImproves-1.73
DePaul University Fatigue Questionnaire : Difficulty finding the right wordWorsen2.17
DePaul University Fatigue Questionnaire : Difficulty staying asleepImproves-2.58
DePaul University Fatigue Questionnaire : FatigueImproves-2.39
DePaul University Fatigue Questionnaire : Forgetting what you are trying to sayImproves-3.01
DePaul University Fatigue Questionnaire : Impaired Memory & concentrationWorsen2.57
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired Improves-2.36
DePaul University Fatigue Questionnaire : Walking up early in the morning (e.g. 3AM)Worsen1.55
Gender: FemaleWorsen1.21
Gender: MaleWorsen1.21
General: DepressionWorsen1.21
General: FatigueImproves-1.3
General: HeadachesWorsen2
General: Heavy feeling in arms and legsWorsen1
General: Myalgia (pain)Worsen0.59
General: Sinus issues with headachesWorsen1.21
Immune Manifestations: Abdominal PainWorsen1.21
Immune Manifestations: Alcohol IntolerantWorsen2
Immune Manifestations: BloatingImproves-2.81
Immune Manifestations: ConstipationWorsen1.21
Immune Manifestations: general malaiseWorsen1.21
Immune Manifestations: Hair lossWorsen1.21
Immune Manifestations: Inflammation (General)Worsen0.57
Immune Manifestations: Inflammation of skin, eyes or jointsWorsen1.21
Immune Manifestations: medication sensitivities.Worsen1.21
Immune Manifestations: Mucus in the stoolWorsen1.21
Immune Manifestations: new food sensitivitiesWorsen1.92
Immune: Sensitivity to smell/food/medication/chemicalsWorsen1.92
Infection: Epstein-Barr virusWorsen1.21
Infection: Human Herpesvirus 6 (HHV6)Improves-0.86
Infection: MycoplasmaWorsen1.21
Infection: Parasite - OtherWorsen1.92
Joint: RednessImproves-2.49
Joint: Stiffness and swellingWorsen2.05
Joint: TendernessWorsen1.21
Neurocognitive: Absent-mindedness or forgetfulnessWorsen1.21
Neurocognitive: Brain FogImproves-2.81
Neurocognitive: Can only focus on one thing at a timeWorsen2.05
Neurocognitive: Difficulty expressing thoughtsWorsen1.92
Neurocognitive: Difficulty paying attention for a long period of timeWorsen1.21
Neurocognitive: Difficulty understanding thingsWorsen1.24
Neurocognitive: Problems remembering thingsWorsen1.21
Neurocognitive: Slowness of thoughtWorsen1.21
Neurocognitive: Unable to focus vision and/or attentionImproves-2.81
Neuroendocrine Manifestations: cold extremitiesImproves-0.66
Neuroendocrine Manifestations: Dry Eye (Sicca or Sjogren Syndrome)Improves-2.52
Neuroendocrine Manifestations: Excessive adrenalineWorsen1.68
Neuroendocrine Manifestations: intolerance of extremes of heat and coldImproves-2.34
Neuroendocrine Manifestations: marked weight change Worsen1.92
Neuroendocrine Manifestations: Muscle weakness Worsen1.24
Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin)Improves-2.81
Neuroendocrine Manifestations: Rapid muscular fatiguabilityWorsen1.24
Neuroendocrine Manifestations: subnormal body temperatureWorsen1.21
Neuroendocrine Manifestations: sweating episodesWorsen1.21
Neuroendocrine Manifestations: worsening of symptoms with stress.Worsen1.21
Neuroendocrine: Alcohol intoleranceImproves-2.5
Neuroendocrine: Cold limbs (e.g. arms, legs hands)Worsen1.92
Neuroendocrine: Feeling hot or cold for no reasonWorsen1.24
Neurological-Audio: hypersensitivity to noiseWorsen2.17
Neurological-Audio: Tinnitus (ringing in ear)Improves-2.5
Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep)Improves-2.42
Neurological-Sleep: InsomniaImproves-2.81
Neurological-Sleep: Night SweatsWorsen1.21
Neurological-Sleep: Vivid Dreams/NightmaresWorsen1.64
Neurological-Vision: inability to focus eye/visionImproves-2.81
Neurological-Vision: photophobia (Light Sensitivity)Worsen1.21
Neurological: Cognitive/Sensory OverloadImproves-0.66
Neurological: Difficulty processing information (Understanding)Worsen1.92
Neurological: Difficulty readingWorsen1.21
Neurological: DysautonomiaWorsen1.92
Neurological: emotional overloadWorsen1.92
Neurological: Executive Decision Making (Difficulty making)Worsen1.21
Neurological: Impairment of concentrationWorsen1.21
Neurological: Joint hypermobilityImproves-3.12
Neurological: Seasonal Affective Disorder (SAD)Worsen1.21
Neurological: Short-term memory issuesWorsen1.98
Neurological: Slowed speechWorsen2.38
Neurological: Word-finding problemsImproves-2.61
Official Diagnosis: Allergic Rhinitis (Hay Fever)Improves-1.66
Official Diagnosis: Autoimmune DiseaseWorsen0.57
Official Diagnosis: Chronic Fatigue SyndromeWorsen1.21
Official Diagnosis: Irritable Bowel SyndromeImproves-3.1
Official Diagnosis: Mast Cell DysfunctionWorsen2.8
Onset: 2010-2020Worsen1.21
Onset: GradualImproves-1.48
Pain: Chest painWorsen3.21
Pain: Joint painWorsen2.02
Pain: Pain or aching in musclesWorsen1.92
Pain: Sensitivity to painImproves-1.25
Post-exertional malaise: Difficulty reading after mild physical or mental activityImproves-1.69
Post-exertional malaise: GeneralWorsen1.24
Post-exertional malaise: Mentally tired after the slightest effortWorsen1.24
Post-exertional malaise: Muscle fatigue after mild physical activityWorsen1.21
Post-exertional malaise: Physically drained or sick after mild activityWorsen1.92
Post-exertional malaise: Physically tired after minimum exerciseWorsen1.21
Post-exertional malaise: Post-exertional malaiseWorsen1.21
Post-exertional malaise: Rapid cognitive fatigability, Improves-0.66
Post-exertional malaise: Rapid muscular fatigability, Worsen1.24
Post-exertional malaise: Worsening of symptoms after mild mental activityWorsen1.24
Post-exertional malaise: Worsening of symptoms after mild physical activityWorsen1.21
Sleep: Daytime drowsinessImproves-2.81
Sleep: Problems falling asleepWorsen1.92
Sleep: Problems staying asleepWorsen2.05
Sleep: Unrefreshed sleepImproves-1.3
Sleep: Waking up early in the morning (e.g. 3 AM)Improves-2.5

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomImpactPredictor of Bacteria Shift
ADHDWorsen3.59
Allergic Rhinitis (Hay Fever)Improves-2.75
Alzheimer's diseaseWorsen3.7
Amyotrophic lateral sclerosis (ALS) Motor NeuronWorsen4.37
Ankylosing spondylitisImproves-4.1
Anorexia NervosaWorsen1.1
AsthmaImproves-2.52
AtherosclerosisImproves-2.94
AutismWorsen5.57
Barrett esophagus cancerWorsen3.52
Bipolar DisorderImproves-3.12
Brain TraumaImproves-2.86
CarcinomaImproves-2.83
Celiac DiseaseWorsen3.32
Cerebral PalsyImproves-2.83
Chronic Fatigue SyndromeImproves-3.56
Chronic Kidney DiseaseWorsen3.54
Chronic Urticaria (Hives)Improves-2.55
Colorectal CancerImproves-3.86
Coronary artery disease Worsen3.16
COVID-19Improves-2.39
Crohn's DiseaseWorsen0.45
DepressionWorsen3.96
EczemaWorsen3.52
EpilepsyWorsen3.45
FibromyalgiaImproves-1.69
Functional constipation / chronic idiopathic constipationWorsen2.57
gallstone disease (gsd)Improves-2.01
Gastroesophageal reflux disease (Gerd) including Barrett's esophagusWorsen3.46
GoutWorsen2.96
Graves' diseaseWorsen3.53
Hashimoto's thyroiditisImproves-1.95
High Blood PressureImproves-2.3
Histamine IssuesImproves-1.07
Histamine Issues From UbiomeWorsen1.61
hypercholesterolemia (High Cholesterol)Worsen2.85
Hyperlipidemia (High Blood Fats)Improves-3.57
IgA nephropathy (IgAN)Worsen2.83
Inflammatory Bowel DiseaseImproves-3.79
Irritable Bowel SyndromeWorsen2.94
Liver CirrhosisImproves-4.33
ME/CFS with IBSImproves-3.5
ME/CFS without IBSImproves-3.62
Multiple SclerosisImproves-1.56
neuropsychiatric disorders (PANDAS, PANS)Worsen2.85
Nonalcoholic Fatty Liver Disease (nafld) NonalcoholicImproves-4.91
ObesityImproves-3.04
OsteoarthritisImproves-2.83
OsteoporosisWorsen2.76
Parkinson's DiseaseImproves-4.24
PsoriasisImproves-3.78
rheumatoid arthritis (RA),Spondyloarthritis (SpA)Improves-3.96
SchizophreniaWorsen3.29
Sjögren syndromeImproves-2.72
Small Intestinal Bacterial Overgrowth (SIBO)Improves-2.83
Systemic Lupus ErythematosusImproves-3.05
Type 1 DiabetesWorsen4.61
Type 2 DiabetesWorsen2.32
Ulcerative colitisImproves-4.34

Bacteria Impacted

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Lachnospiraceae family Decreases 📓 Source Study
Ruminococcaceae family Decreases 📓 Source Study
Streptococcaceae family Decreases 📓 Source Study
Veillonellaceae family Decreases 📓 Source Study
Porphyromonadaceae family Increases 📓 Source Study
Prevotellaceae family Increases 📓 Source Study
Dialister genus Decreases 📓 Source Study
Eisenbergiella genus Decreases 📓 Source Study
Streptococcus genus Decreases 📓 Source Study
Subdoligranulum genus Decreases 📓 Source Study
Acetanaerobacterium genus Decreases 👪 Source Study
Acetatifactor genus Decreases 👪 Source Study
Acetitomaculum genus Decreases 👪 Source Study
Agathobacter genus Decreases 👪 Source Study
Agathobaculum genus Decreases 👪 Source Study
Allisonella genus Decreases 👪 Source Study
Anaerobium genus Decreases 👪 Source Study
Anaerobutyricum genus Decreases 👪 Source Study
Anaerocolumna genus Decreases 👪 Source Study
Anaerofilum genus Decreases 👪 Source Study
Anaeroglobus genus Decreases 👪 Source Study
Anaeromassilibacillus genus Decreases 👪 Source Study
Anaerosporobacter genus Decreases 👪 Source Study
Anaerotaenia genus Decreases 👪 Source Study
Anaerotignum genus Decreases 👪 Source Study
Angelakisella genus Decreases 👪 Source Study
Bittarella genus Decreases 👪 Source Study
Candidatus Soleaferrea genus Decreases 👪 Source Study
Caproiciproducens genus Decreases 👪 Source Study
Catonella genus Decreases 👪 Source Study
Cellulosilyticum genus Decreases 👪 Source Study
Eisenbergiella genus Decreases 👪 Source Study
Ethanoligenens genus Decreases 👪 Source Study
Faecalicatena genus Decreases 👪 Source Study
Flavonifractor genus Decreases 👪 Source Study
Fournierella genus Decreases 👪 Source Study
Fusicatenibacter genus Decreases 👪 Source Study
Gemmiger genus Decreases 👪 Source Study
Gorbachella genus Decreases 👪 Source Study
Herbinix genus Decreases 👪 Source Study
Hespellia genus Decreases 👪 Source Study
Hydrogenoanaerobacterium genus Decreases 👪 Source Study
Johnsonella genus Decreases 👪 Source Study
Lachnoanaerobaculum genus Decreases 👪 Source Study
Lachnobacterium genus Decreases 👪 Source Study
Lachnotalea genus Decreases 👪 Source Study
Lactovum genus Decreases 👪 Source Study
Merdimonas genus Decreases 👪 Source Study
Mobilitalea genus Decreases 👪 Source Study
Moryella genus Decreases 👪 Source Study
Murimonas genus Decreases 👪 Source Study
Negativibacillus genus Decreases 👪 Source Study
Negativicoccus genus Decreases 👪 Source Study
Neglecta genus Decreases 👪 Source Study
Oribacterium genus Decreases 👪 Source Study
Papillibacter genus Decreases 👪 Source Study
Parasporobacterium genus Decreases 👪 Source Study
Phocea genus Decreases 👪 Source Study
Pseudoflavonifractor genus Decreases 👪 Source Study
Robinsoniella genus Decreases 👪 Source Study
Ruthenibacterium genus Decreases 👪 Source Study
Sellimonas genus Decreases 👪 Source Study
Shuttleworthia genus Decreases 👪 Source Study
Sporobacter genus Decreases 👪 Source Study
Sporobacterium genus Decreases 👪 Source Study
Stomatobaculum genus Decreases 👪 Source Study
Syntrophococcus genus Decreases 👪 Source Study
Tyzzerella genus Decreases 👪 Source Study
Alloprevotella genus Increases 👪 Source Study
Falsiporphyromonas genus Increases 👪 Source Study
Fermentimonas genus Increases 👪 Source Study
Gabonibacter genus Increases 👪 Source Study
Massiliprevotella genus Increases 👪 Source Study
Metaprevotella genus Increases 👪 Source Study
Microbacter genus Increases 👪 Source Study
Paraprevotella genus Increases 👪 Source Study
Petrimonas genus Increases 👪 Source Study
Prevotellamassilia genus Increases 👪 Source Study
Sanguibacteroides genus Increases 👪 Source Study
Barnesiella genus Increases 📓 Source Study
Odoribacter genus Increases 📓 Source Study
Paraprevotella genus Increases 📓 Source Study
Firmicutes phylum Decreases 📓 Source Study
Bacteroidota phylum Increases 📓 Source Study
Cyanobacteria phylum Increases 📓 Source Study
ATCC 43138 species Decreases 👪 Source Study
CCUG 46149 species Decreases 👪 Source Study
CCUG 48363 species Decreases 👪 Source Study
CCUG 55896 species Decreases 👪 Source Study
CGMCC 1.15531 species Decreases 👪 Source Study
CGMCC 1.15532 species Decreases 👪 Source Study
CGMCC 1.15533 species Decreases 👪 Source Study
CGMCC 1.15534 species Decreases 👪 Source Study
CGMCC 1.15667 species Decreases 👪 Source Study
Dialister invisus species Decreases 👪 Source Study
Dialister micraerophilus species Decreases 👪 Source Study
Dialister pneumosintes species Decreases 👪 Source Study
Dialister propionicifaciens species Decreases 👪 Source Study
Dialister sp. species Decreases 👪 Source Study
Dialister sp. E2_20 species Decreases 👪 Source Study
Dialister sp. Marseille-P5638 species Decreases 👪 Source Study
Dialister sp. S4-23 species Decreases 👪 Source Study
Dialister sp. S7MSR5 species Decreases 👪 Source Study
Dialister succinatiphilus species Decreases 👪 Source Study
DSM 104980 species Decreases 👪 Source Study
DSM 18963 species Decreases 👪 Source Study
DSM 26920 species Decreases 👪 Source Study
Eisenbergiella massiliensis species Decreases 👪 Source Study
Eisenbergiella sp. species Decreases 👪 Source Study
Eisenbergiella tayi species Decreases 👪 Source Study
Eubacterium uniforme species Decreases 👪 Source Study
Streptococcus acidominimus species Decreases 👪 Source Study
Streptococcus anginosus group species Decreases 👪 Source Study
Streptococcus canis species Decreases 👪 Source Study
Streptococcus cristatus species Decreases 👪 Source Study
Streptococcus danieliae species Decreases 👪 Source Study
Streptococcus dentapri species Decreases 👪 Source Study
Streptococcus dentasini species Decreases 👪 Source Study
Streptococcus didelphis species Decreases 👪 Source Study
Streptococcus entericus species Decreases 👪 Source Study
Streptococcus G418 species Decreases 👪 Source Study
Streptococcus gallolyticus species Decreases 👪 Source Study
Streptococcus hyointestinalis species Decreases 👪 Source Study
Streptococcus hyovaginalis species Decreases 👪 Source Study
Streptococcus infantarius species Decreases 👪 Source Study
Streptococcus infantis species Decreases 👪 Source Study
Streptococcus iniae species Decreases 👪 Source Study
Streptococcus marimammalium species Decreases 👪 Source Study
Streptococcus massiliensis species Decreases 👪 Source Study
Streptococcus merionis species Decreases 👪 Source Study
Streptococcus milleri species Decreases 👪 Source Study
Streptococcus mitis species Decreases 👪 Source Study
Streptococcus oralis species Decreases 👪 Source Study
Streptococcus orisasini species Decreases 👪 Source Study
Streptococcus orisratti species Decreases 👪 Source Study
Streptococcus parauberis species Decreases 👪 Source Study
Streptococcus pharyngis species Decreases 👪 Source Study
Streptococcus phocae species Decreases 👪 Source Study
Streptococcus pluranimalium species Decreases 👪 Source Study
Streptococcus plurextorum species Decreases 👪 Source Study
Streptococcus porcorum species Decreases 👪 Source Study
Streptococcus pseudopneumoniae species Decreases 👪 Source Study
Streptococcus pseudoporcinus species Decreases 👪 Source Study
Streptococcus rupicaprae species Decreases 👪 Source Study
Streptococcus sanguinis species Decreases 👪 Source Study
Streptococcus seminale species Decreases 👪 Source Study
Streptococcus sobrinus species Decreases 👪 Source Study
Streptococcus sp. 2_1_36FAA species Decreases 👪 Source Study
Streptococcus sp. 2011_Ileo_MS_A12 species Decreases 👪 Source Study
Streptococcus sp. 2011_Ileo_MS_C3 species Decreases 👪 Source Study
Streptococcus sp. 2011_Oral_MS_B3 species Decreases 👪 Source Study
Streptococcus sp. 2011_Oral_MS_D12 species Decreases 👪 Source Study
Streptococcus sp. 2011_Oral_MS_E1 species Decreases 👪 Source Study
Streptococcus sp. A12 species Decreases 👪 Source Study
Streptococcus sp. AS14 species Decreases 👪 Source Study
Streptococcus sp. BS35b species Decreases 👪 Source Study
Streptococcus sp. canine oral taxon 279 species Decreases 👪 Source Study
Streptococcus sp. F0441 species Decreases 👪 Source Study
Streptococcus sp. F0442 species Decreases 👪 Source Study
Streptococcus sp. FDAARGOS_192 species Decreases 👪 Source Study
Streptococcus sp. HPA1 species Decreases 👪 Source Study
Streptococcus sp. HPH0090 species Decreases 👪 Source Study
Streptococcus sp. HSISB1 species Decreases 👪 Source Study
Streptococcus sp. HSISM1 species Decreases 👪 Source Study
Streptococcus sp. HSISS1 species Decreases 👪 Source Study
Streptococcus sp. HSISS2 species Decreases 👪 Source Study
Streptococcus sp. I-G2 species Decreases 👪 Source Study
Streptococcus sp. JS71 species Decreases 👪 Source Study
Streptococcus sp. M143 species Decreases 👪 Source Study
Streptococcus sp. NPS 308 species Decreases 👪 Source Study
Streptococcus sp. oral taxon 064 species Decreases 👪 Source Study
Streptococcus sp. oral taxon 071 species Decreases 👪 Source Study
Streptococcus sp. oral taxon 431 species Decreases 👪 Source Study
Streptococcus sp. oral taxon G62 species Decreases 👪 Source Study
Streptococcus sp. oral taxon G63 species Decreases 👪 Source Study
Streptococcus sp. S16-08 species Decreases 👪 Source Study
Streptococcus sp. TM013 species Decreases 👪 Source Study
Streptococcus sp. Z15 species Decreases 👪 Source Study
Streptococcus suis species Decreases 👪 Source Study
Streptococcus troglodytae species Decreases 👪 Source Study
Streptococcus troglodytidis species Decreases 👪 Source Study
Streptococcus uberis species Decreases 👪 Source Study
Streptococcus urinalis species Decreases 👪 Source Study
Streptococcus vestibularis species Decreases 👪 Source Study
Streptococcus viridans species Decreases 👪 Source Study
Subdoligranulum sp. species Decreases 👪 Source Study
Subdoligranulum sp. 4_3_54A2FAA species Decreases 👪 Source Study
Subdoligranulum variabile species Decreases 👪 Source Study
Barnesiella intestinihominis species Increases 👪 Source Study
Barnesiella sp. EBA4-14 species Increases 👪 Source Study
Barnesiella sp. S496 species Increases 👪 Source Study
Barnesiella viscericola species Increases 👪 Source Study
Odoribacter denticanis species Increases 👪 Source Study
Odoribacter laneus species Increases 👪 Source Study
Odoribacter sp. species Increases 👪 Source Study
Paraprevotella clara species Increases 👪 Source Study
Paraprevotella sp. species Increases 👪 Source Study
Paraprevotella xylaniphila species Increases 👪 Source Study

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This is an Academic site. It generates theoretical models of what may benefit a specific microbiome results.