b animalis lactis (probiotics)
We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.
| Symptom | Impact | Predictor of Bacteria Shift |
|---|---|---|
| Age: 0-10 | Improves | -3.62 |
| Age: 20-30 | Worsen | 3.92 |
| Age: 30-40 | Worsen | 2.91 |
| Age: 40-50 | Worsen | 1.16 |
| Age: 50-60 | Worsen | 1.16 |
| Age: 60-70 | Improves | -2.02 |
| Asymptomatic: Live in house with person with probable microbiome dysfunction | Improves | -1.16 |
| Asymptomatic: Minor Health Issues (a few symptoms only) | Worsen | 1.16 |
| Asymptomatic: No Health Issues | Worsen | 2.8 |
| Autism: Official Diagnosis | Improves | -1.16 |
| Autonomic Manifestations: cardiac arrhythmias | Worsen | 3.57 |
| Autonomic Manifestations: irritable bowel syndrome | Worsen | 1.16 |
| Autonomic Manifestations: light-headedness | Worsen | 2.8 |
| Autonomic Manifestations: Orthostatic intolerance | Improves | -1.16 |
| Autonomic Manifestations: palpitations | Worsen | 1.16 |
| Autonomic Manifestations: Postural orthostatic tachycardia syndrome (POTS) | Improves | -1.16 |
| Autonomic Manifestations: urinary frequency dysfunction | Worsen | 1.16 |
| Autonomic: Blurred or tunnel vision after standing | Worsen | 1.16 |
| Autonomic: Dizziness or fainting | Worsen | 1.16 |
| Autonomic: Heart rate increase after standing | Improves | -1.16 |
| Autonomic: Inability to tolerate an upright position | Improves | -1.16 |
| Autonomic: Irregular heartbeats | Worsen | 2.8 |
| Autonomic: Nausea | Worsen | 1.96 |
| Autonomic: Ocassional Tachycardia (Rapid heart beat) | Worsen | 1.16 |
| Autonomic: Shortness of breath | Worsen | 1.16 |
| Blood Type: A Positive | Improves | -1.16 |
| Blood Type: O Positive | Improves | -1.16 |
| Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grinding | Improves | -1.16 |
| Comorbid-Mouth: Dry Mouth | Worsen | 1.16 |
| Comorbid-Mouth: Gingivits / Gum Disease | Worsen | 2.75 |
| Comorbid-Mouth: Mouth Sores | Improves | -1.16 |
| Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndrome | Improves | -1.16 |
| Comorbid: Constipation and Diarrohea (not explosions) | Worsen | 2.93 |
| Comorbid: Constipation and Explosions (not diarrohea) | Worsen | 2.74 |
| Comorbid: Fibromyalgia | Improves | -1.16 |
| Comorbid: High Anxiety | Improves | -1.16 |
| Comorbid: Histamine or Mast Cell issues | Improves | -1.16 |
| Comorbid: Hypothyroidism | Improves | -1.16 |
| Comorbid: Inflammatory bowel disease | Improves | -2.99 |
| Comorbid: Methylation issues (MTHFR) | Worsen | 1.16 |
| Comorbid: Migraine | Worsen | 3.96 |
| Comorbid: Mold Sensitivity / Exposure | Improves | -1.16 |
| Comorbid: Multiple Chemical Sensitivity | Improves | -2.97 |
| Comorbid: Small intestinal bacterial overgrowth (SIBO) | Worsen | 1.16 |
| Comorbid: Snoring (NOT Sleep Apnea | Improves | -1.16 |
| Condition: ME/CFS with IBS | Worsen | 2.93 |
| DePaul University Fatigue Questionnaire : Abdomen pain | Worsen | 0.74 |
| DePaul University Fatigue Questionnaire : Allergies | Worsen | 3.73 |
| DePaul University Fatigue Questionnaire : Anxiety/tension | Worsen | 3.76 |
| DePaul University Fatigue Questionnaire : Chemical sensitivity | Worsen | 2.93 |
| DePaul University Fatigue Questionnaire : Depression | Worsen | 3.54 |
| DePaul University Fatigue Questionnaire : Difficulty comprehending Information | Worsen | 3.54 |
| DePaul University Fatigue Questionnaire : Difficulty falling asleep | Worsen | 2.93 |
| DePaul University Fatigue Questionnaire : Difficulty finding the right word | Worsen | 4.25 |
| DePaul University Fatigue Questionnaire : Difficulty staying asleep | Worsen | 3.04 |
| DePaul University Fatigue Questionnaire : Dizziness | Worsen | 2.93 |
| DePaul University Fatigue Questionnaire : Fatigue | Worsen | 3.97 |
| DePaul University Fatigue Questionnaire : Forgetting what you are trying to say | Worsen | 3.47 |
| DePaul University Fatigue Questionnaire : Impaired Memory & concentration | Worsen | 3.27 |
| DePaul University Fatigue Questionnaire : Racing heart | Worsen | 2.93 |
| DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired | Worsen | 2.26 |
| DePaul University Fatigue Questionnaire : Upset stomach | Worsen | 2.93 |
| DePaul University Fatigue Questionnaire : Walking up early in the morning (e.g. 3AM) | Worsen | 3.35 |
| Gender: Female | Worsen | 3.48 |
| Gender: Male | Improves | -1.16 |
| General: Depression | Improves | -1.16 |
| General: Fatigue | Worsen | 3.61 |
| General: Headaches | Worsen | 1.16 |
| General: Heavy feeling in arms and legs | Improves | -2.74 |
| General: Myalgia (pain) | Worsen | 1.16 |
| General: Sinus issues with headaches | Improves | -1.16 |
| Immune Manifestations: Abdominal Pain | Worsen | 1.16 |
| Immune Manifestations: Alcohol Intolerant | Improves | -1.16 |
| Immune Manifestations: Bloating | Worsen | 3.5 |
| Immune Manifestations: Constipation | Worsen | 2.99 |
| Immune Manifestations: Diarrhea | Worsen | 1.16 |
| Immune Manifestations: general malaise | Worsen | 2.74 |
| Immune Manifestations: Hair loss | Worsen | 1.16 |
| Immune Manifestations: hives | Worsen | 2.65 |
| Immune Manifestations: Inflammation (General) | Improves | -1.16 |
| Immune Manifestations: Inflammation of skin, eyes or joints | Improves | -1.16 |
| Immune Manifestations: medication sensitivities. | Improves | -1.16 |
| Immune Manifestations: Mucus in the stool | Improves | -1.16 |
| Immune Manifestations: new food sensitivities | Worsen | 1.16 |
| Immune Manifestations: tender lymph nodes | Improves | -1.16 |
| Immune: Chronic Sinusitis | Worsen | 2.83 |
| Immune: Recurrent Sore throat | Improves | -1.16 |
| Immune: Sensitivity to smell/food/medication/chemicals | Worsen | 2.8 |
| Immune: Viral infections with prolonged recovery periods | Improves | -1.16 |
| Infection: Epstein-Barr virus | Improves | -2.99 |
| Infection: Human Herpesvirus 6 (HHV6) | Improves | -2.07 |
| Infection: Mycoplasma | Improves | -1.16 |
| Infection: Parasite - Other | Improves | -2.8 |
| Joint: Redness | Improves | -2.99 |
| Joint: Stiffness and swelling | Improves | -1.16 |
| Joint: Sudden and severe episodes of pain | Worsen | 1.16 |
| Joint: Tenderness | Improves | -1.16 |
| Neurocognitive: Absent-mindedness or forgetfulness | Worsen | 2.8 |
| Neurocognitive: Brain Fog | Improves | -1.16 |
| Neurocognitive: Can only focus on one thing at a time | Worsen | 1.16 |
| Neurocognitive: Difficulty expressing thoughts | Worsen | 2.49 |
| Neurocognitive: Difficulty paying attention for a long period of time | Worsen | 2.8 |
| Neurocognitive: Difficulty understanding things | Improves | -1.16 |
| Neurocognitive: Problems remembering things | Worsen | 1.16 |
| Neurocognitive: Slowness of thought | Worsen | 0.97 |
| Neurocognitive: Unable to focus vision and/or attention | Worsen | 1.16 |
| Neuroendocrine Manifestations: abnormal appetite | Worsen | 1.16 |
| Neuroendocrine Manifestations: Air Hunger | Improves | -1.16 |
| Neuroendocrine Manifestations: cold extremities | Improves | -1.16 |
| Neuroendocrine Manifestations: Dry Eye (Sicca or Sjogren Syndrome) | Worsen | 1.16 |
| Neuroendocrine Manifestations: intolerance of extremes of heat and cold | Improves | -1.16 |
| Neuroendocrine Manifestations: marked weight change | Worsen | 1.16 |
| Neuroendocrine Manifestations: Muscle weakness | Improves | -1.16 |
| Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin) | Improves | -1.16 |
| Neuroendocrine Manifestations: Rapid muscular fatiguability | Improves | -1.16 |
| Neuroendocrine Manifestations: recurrent feelings of feverishness | Improves | -1.16 |
| Neuroendocrine Manifestations: subnormal body temperature | Worsen | 2.8 |
| Neuroendocrine Manifestations: sweating episodes | Improves | -1.16 |
| Neuroendocrine Manifestations: worsening of symptoms with stress. | Worsen | 3.5 |
| Neuroendocrine: Alcohol intolerance | Improves | -1.16 |
| Neuroendocrine: Chills or shivers | Worsen | 1.16 |
| Neuroendocrine: Cold limbs (e.g. arms, legs hands) | Improves | -1.16 |
| Neuroendocrine: Feeling hot or cold for no reason | Improves | -1.16 |
| Neuroendocrine: Lack of appetite | Worsen | 1.16 |
| Neuroendocrine: Lost or gained weight without trying | Worsen | 1.16 |
| Neuroendocrine: Sweating hands | Worsen | 1.16 |
| Neuroendocrine: Temperature fluctuations throughout the day | Worsen | 1.16 |
| Neurological-Audio: hypersensitivity to noise | Improves | -1.16 |
| Neurological-Audio: Tinnitus (ringing in ear) | Improves | -1.16 |
| Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep) | Worsen | 3.34 |
| Neurological-Sleep: Insomnia | Improves | -1.16 |
| Neurological-Sleep: Night Sweats | Improves | -1.16 |
| Neurological-Sleep: Sleep Apnea | Improves | -1.16 |
| Neurological-Sleep: Vivid Dreams/Nightmares | Worsen | 2.95 |
| Neurological-Vision: Blurred Vision | Improves | -2.81 |
| Neurological-Vision: inability to focus eye/vision | Worsen | 2.74 |
| Neurological-Vision: photophobia (Light Sensitivity) | Improves | -1.16 |
| Neurological: Cognitive/Sensory Overload | Worsen | 2.8 |
| Neurological: Confusion | Worsen | 1.16 |
| Neurological: Difficulty processing information (Understanding) | Worsen | 1.16 |
| Neurological: Difficulty reading | Worsen | 2.74 |
| Neurological: Dysautonomia | Improves | -1.16 |
| Neurological: emotional overload | Worsen | 2.8 |
| Neurological: Executive Decision Making (Difficulty making) | Worsen | 2.49 |
| Neurological: fasciculations | Improves | -3.25 |
| Neurological: Impairment of concentration | Worsen | 3.5 |
| Neurological: Joint hypermobility | Improves | -1.16 |
| Neurological: Myoclonic jerks or seizures | Worsen | 2.65 |
| Neurological: Neuropathy | Improves | -1.16 |
| Neurological: Seasonal Affective Disorder (SAD) | Improves | -1.16 |
| Neurological: Short-term memory issues | Worsen | 2.8 |
| Neurological: Slowed speech | Improves | -1.16 |
| Neurological: Spatial instability and disorientation | Worsen | 1.16 |
| Neurological: Word-finding problems | Improves | -1.16 |
| Official Diagnosis: Allergic Rhinitis (Hay Fever) | Improves | -1.16 |
| Official Diagnosis: Autoimmune Disease | Improves | -1.16 |
| Official Diagnosis: Chronic Fatigue Syndrome | Worsen | 1.16 |
| Official Diagnosis: Irritable Bowel Syndrome | Improves | -1.16 |
| Official Diagnosis: Mast Cell Dysfunction | Improves | -1.16 |
| Onset: 2000-2010 | Worsen | 1.16 |
| Onset: 2010-2020 | Worsen | 2.74 |
| Onset: Gradual | Worsen | 2.8 |
| Other: Sensitivity to mold | Improves | -1.16 |
| Pain: Aching of the eyes or behind the eyes | Improves | -1.16 |
| Pain: Chest pain | Worsen | 1.16 |
| Pain: Eye pain | Improves | -1.16 |
| Pain: Joint pain | Improves | -1.16 |
| Pain: Myofascial pain | Improves | -1.16 |
| Pain: Pain or aching in muscles | Worsen | 1.16 |
| Pain: Sensitivity to pain | Improves | -1.16 |
| Post-exertional malaise: Difficulty reading after mild physical or mental activity | Improves | -1.16 |
| Post-exertional malaise: General | Improves | -1.16 |
| Post-exertional malaise: Mentally tired after the slightest effort | Worsen | 3.52 |
| Post-exertional malaise: Muscle fatigue after mild physical activity | Improves | -1.16 |
| Post-exertional malaise: Physically drained or sick after mild activity | Worsen | 3.02 |
| Post-exertional malaise: Physically tired after minimum exercise | Improves | -1.16 |
| Post-exertional malaise: Post-exertional malaise | Improves | -1.16 |
| Post-exertional malaise: Rapid cognitive fatigability, | Worsen | 1.16 |
| Post-exertional malaise: Rapid muscular fatigability, | Worsen | 1.16 |
| Post-exertional malaise: Worsening of symptoms after mild mental activity | Improves | -1.16 |
| Post-exertional malaise: Worsening of symptoms after mild physical activity | Improves | -1.16 |
| Sleep: Daytime drowsiness | Worsen | 3.36 |
| Sleep: Need to nap daily | Worsen | 1.16 |
| Sleep: Problems falling asleep | Worsen | 1.16 |
| Sleep: Problems staying asleep | Worsen | 3 |
| Sleep: Unrefreshed sleep | Worsen | 3.61 |
| Sleep: Waking up early in the morning (e.g. 3 AM) | Improves | -1.16 |
We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is according to the microbiome shifts reported in studies. Clinical studies may show different results
| Symptom | Impact | Predictor of Bacteria Shift |
|---|---|---|
| Acne | Improves | -4.22 |
| ADHD | Worsen | 4.48 |
| Allergic Rhinitis (Hay Fever) | Improves | -3.89 |
| Allergies | Improves | -3.46 |
| Alzheimer's disease | Worsen | 4.36 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | Worsen | 4.15 |
| Ankylosing spondylitis | Improves | -4.5 |
| Anorexia Nervosa | Improves | -3.42 |
| Asthma | Improves | -3.53 |
| Atherosclerosis | Worsen | 3.63 |
| Autism | Improves | -3.83 |
| Barrett esophagus cancer | Worsen | 4.11 |
| Brain Trauma | Worsen | 2.7 |
| Carcinoma | Improves | -3.49 |
| Celiac Disease | Improves | -4.92 |
| Cerebral Palsy | Worsen | 3.48 |
| Chronic Fatigue Syndrome | Improves | -4.84 |
| Chronic Kidney Disease | Improves | -2.56 |
| Chronic Urticaria (Hives) | Improves | -3.01 |
| Colorectal Cancer | Improves | -4.37 |
| Coronary artery disease | Improves | -2.66 |
| COVID-19 | Improves | -3.81 |
| Crohn's Disease | Improves | -3.6 |
| deep vein thrombosis | Improves | -2.86 |
| Depression | Improves | -4.28 |
| Eczema | Improves | -4.25 |
| Epilepsy | Improves | -4.1 |
| Fibromyalgia | Improves | -3.89 |
| Functional constipation / chronic idiopathic constipation | Worsen | 2.88 |
| gallstone disease (gsd) | Worsen | 2.56 |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | Worsen | 3.73 |
| Graves' disease | Worsen | 3.78 |
| Hashimoto's thyroiditis | Improves | -3.92 |
| Histamine Issues | Worsen | 1.48 |
| Histamine Issues From Ubiome | Improves | -2.72 |
| hypercholesterolemia (High Cholesterol) | Improves | -2.87 |
| Hyperlipidemia (High Blood Fats) | Worsen | 1.68 |
| hypertension (High Blood Pressure | Improves | -2.71 |
| IgA nephropathy (IgAN) | Improves | -3.47 |
| Inflammatory Bowel Disease | Improves | -4.31 |
| Irritable Bowel Syndrome | Improves | -4.18 |
| Liver Cirrhosis | Improves | -3.2 |
| Long COVID | Worsen | 2.94 |
| ME/CFS with IBS | Improves | -3.91 |
| ME/CFS without IBS | Improves | -3.91 |
| Metabolic Syndrome | Improves | -0.41 |
| Multiple Sclerosis | Worsen | 3.55 |
| Multiple system atrophy (MSA) | Worsen | 3.47 |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | Improves | -4.21 |
| NonCeliac Gluten Sensitivity | Improves | -2.88 |
| Obesity | Improves | -5.21 |
| obsessive-compulsive disorder | Improves | -4.15 |
| Osteoarthritis | Improves | -2.83 |
| Osteoporosis | Improves | -2.75 |
| Parkinson's Disease | Worsen | 6.11 |
| Psoriasis | Worsen | 4.25 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | Improves | -4.57 |
| Rosacea | Worsen | 1.3 |
| Schizophrenia | Worsen | 2.57 |
| Sjögren syndrome | Improves | -3.67 |
| Sleep Apnea | Worsen | 3.67 |
| Small Intestinal Bacterial Overgrowth (SIBO) | Improves | -3.33 |
| Stress / posttraumatic stress disorder | Improves | -3.22 |
| Systemic Lupus Erythematosus | Improves | -4.46 |
| Type 1 Diabetes | Improves | -3.65 |
| Type 2 Diabetes | Improves | -3.18 |
| Ulcerative colitis | Improves | -4.88 |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
This is an Academic site. It generates theoretical models of what may benefit a specific microbiome results.