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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomImpactPredictor of Bacteria Shift
Age: 0-10Worsen2.93
Age: 20-30Improves-3.55
Age: 30-40Improves-2.71
Age: 40-50Worsen1.43
Asymptomatic: Live in house with person with probable microbiome dysfunctionWorsen1.59
Asymptomatic: No Health IssuesImproves-2.95
Autism: Official DiagnosisImproves-3.24
Autonomic Manifestations: irritable bowel syndromeWorsen1.43
Autonomic: Inability to tolerate an upright positionImproves-3.12
Blood Type: A PositiveWorsen2.83
Blood Type: O PositiveImproves-4.01
Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grindingImproves-1.8
Comorbid-Mouth: Dry MouthWorsen1.59
Comorbid: Constipation and Explosions (not diarrohea)Improves-3.63
Comorbid: High AnxietyImproves-3.63
Comorbid: Histamine or Mast Cell issuesImproves-1.8
Comorbid: Inflammatory bowel disease Improves-3.69
Comorbid: MigraineImproves-3.69
Comorbid: Multiple Chemical SensitivityWorsen3.55
Comorbid: Snoring (NOT Sleep ApneaImproves-3.71
Condition: ME/CFS with IBSImproves-2.73
DePaul University Fatigue Questionnaire : AllergiesWorsen2.55
DePaul University Fatigue Questionnaire : Anxiety/tensionImproves-3.06
DePaul University Fatigue Questionnaire : Difficulty falling asleepImproves-2.92
DePaul University Fatigue Questionnaire : Difficulty finding the right wordImproves-3.06
DePaul University Fatigue Questionnaire : FatigueImproves-4.12
DePaul University Fatigue Questionnaire : Forgetting what you are trying to sayImproves-2.73
DePaul University Fatigue Questionnaire : Impaired Memory & concentrationImproves-3.69
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired Improves-3.74
DePaul University Fatigue Questionnaire : Walking up early in the morning (e.g. 3AM)Improves-3.06
Gender: FemaleWorsen1.43
Gender: MaleWorsen1.43
General: DepressionWorsen1.43
General: FatigueWorsen1.43
General: Sinus issues with headachesImproves-1.8
Immune Manifestations: BloatingWorsen1.43
Immune Manifestations: ConstipationWorsen1.43
Immune Manifestations: Inflammation (General)Improves-3.95
Immune Manifestations: Mucus in the stoolImproves-3.55
Infection: Human Herpesvirus 6 (HHV6)Improves-3.02
Joint: RednessWorsen2.63
Joint: Sudden and severe episodes of painWorsen1.85
Joint: TendernessImproves-3.72
Neurocognitive: Absent-mindedness or forgetfulnessWorsen1.43
Neurocognitive: Brain FogWorsen1.43
Neurocognitive: Can only focus on one thing at a timeWorsen1.43
Neurocognitive: Difficulty expressing thoughtsWorsen1.43
Neurocognitive: Difficulty paying attention for a long period of timeWorsen1.43
Neurocognitive: Difficulty understanding thingsWorsen1.43
Neurocognitive: Problems remembering thingsWorsen1.43
Neuroendocrine Manifestations: cold extremitiesWorsen1.43
Neuroendocrine Manifestations: intolerance of extremes of heat and coldWorsen2.87
Neuroendocrine Manifestations: Muscle weakness Worsen2.87
Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin)Improves-2.85
Neuroendocrine Manifestations: worsening of symptoms with stress.Worsen1.43
Neuroendocrine: Cold limbs (e.g. arms, legs hands)Worsen1.43
Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep)Improves-3.05
Neurological-Vision: inability to focus eye/visionImproves-3.1
Neurological: Joint hypermobilityImproves-3.1
Neurological: Short-term memory issuesWorsen2.87
Neurological: Slowed speechWorsen2.63
Neurological: Word-finding problemsWorsen1.43
Official Diagnosis: Allergic Rhinitis (Hay Fever)Improves-3.16
Official Diagnosis: Chronic Fatigue SyndromeWorsen1.43
Official Diagnosis: Irritable Bowel SyndromeImproves-2.73
Official Diagnosis: Mast Cell DysfunctionImproves-3.2
Onset: 2010-2020Worsen1.43
Pain: Pain or aching in musclesWorsen1.43
Pain: Sensitivity to painImproves-3.24
Post-exertional malaise: GeneralWorsen1.43
Post-exertional malaise: Mentally tired after the slightest effortImproves-2.71
Post-exertional malaise: Post-exertional malaiseWorsen1.43
Post-exertional malaise: Rapid cognitive fatigability, Worsen1.43
Post-exertional malaise: Worsening of symptoms after mild physical activityWorsen1.43
Sleep: Need to nap dailyWorsen1.43
Sleep: Problems falling asleepWorsen1.43
Sleep: Problems staying asleepWorsen1.43
Sleep: Unrefreshed sleepImproves-2.69

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomImpactPredictor of Bacteria Shift
AcneWorsen4.22
ADHDImproves-4.87
Allergic Rhinitis (Hay Fever)Worsen2.87
AllergiesWorsen1.74
Alzheimer's diseaseWorsen0.7
Amyotrophic lateral sclerosis (ALS) Motor NeuronImproves-3.88
Ankylosing spondylitisWorsen4.55
Anorexia NervosaWorsen2.9
AsthmaImproves-3.59
AtherosclerosisWorsen2.25
AutismWorsen4.27
Brain TraumaImproves-2.9
CarcinomaWorsen0
Celiac DiseaseWorsen4.5
Cerebral PalsyImproves-3.96
Chronic Fatigue SyndromeWorsen2.75
Chronic Kidney DiseaseWorsen1.3
Chronic Urticaria (Hives)Improves-0.45
Colorectal CancerImproves-3.74
COVID-19Improves-2.92
Crohn's DiseaseImproves-3.65
DepressionImproves-3.57
EczemaWorsen3.82
EpilepsyWorsen2.87
FibromyalgiaWorsen4.24
Functional constipation / chronic idiopathic constipationImproves-3.49
gallstone disease (gsd)Improves-0.26
Hashimoto's thyroiditisWorsen3.39
High Blood PressureWorsen0.12
hypercholesterolemia (High Cholesterol)Worsen2.87
Hyperlipidemia (High Blood Fats)Improves-3.92
hypertension (High Blood PressureWorsen1.79
IgA nephropathy (IgAN)Worsen4.19
Inflammatory Bowel DiseaseWorsen4.63
Irritable Bowel SyndromeWorsen3.92
Liver CirrhosisWorsen4.01
ME/CFS with IBSImproves-0.26
ME/CFS without IBSImproves-3.61
Metabolic SyndromeWorsen2.9
Multiple SclerosisImproves-4.06
Multiple system atrophy (MSA)Improves-2.89
Nonalcoholic Fatty Liver Disease (nafld) NonalcoholicWorsen3.93
NonCeliac Gluten SensitivityWorsen2.88
ObesityWorsen4.88
OsteoarthritisImproves-2.9
OsteoporosisImproves-2.9
Parkinson's DiseaseImproves-6.11
PsoriasisImproves-4.23
rheumatoid arthritis (RA),Spondyloarthritis (SpA)Worsen3.91
RosaceaImproves-1.89
SchizophreniaImproves-2.24
Sjögren syndromeWorsen3.89
Stress / posttraumatic stress disorderImproves-3.26
Systemic Lupus ErythematosusImproves-1.73
Type 1 DiabetesWorsen2.11
Type 2 DiabetesWorsen5.27
Ulcerative colitisWorsen4.85

Bacteria Impacted

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Bacteroidaceae family Decreases 📓 Source Study
Bifidobacteriaceae family Decreases 📓 Source Study
Clostridiaceae family Decreases 📓 Source Study
Peptostreptococcaceae family Decreases 📓 Source Study
Verrucomicrobiaceae family Decreases 📓 Source Study
Akkermansia genus Decreases 📓 Source Study
Bacteroides genus Decreases 📓 Source Study
Bifidobacterium genus Decreases 📓 Source Study
Clostridioides genus Decreases 📓 Source Study
Clostridium genus Decreases 📓 Source Study
Peptoclostridium genus Decreases 📓 Source Study
Acetoanaerobium genus Decreases 👪 Source Study
Aeriscardovia genus Decreases 👪 Source Study
Alkaliphilus genus Decreases 👪 Source Study
Alloscardovia genus Decreases 👪 Source Study
Anaerobacter genus Decreases 👪 Source Study
Anaerorhabdus genus Decreases 👪 Source Study
Anoxynatronum genus Decreases 👪 Source Study
Asaccharospora genus Decreases 👪 Source Study
Beduini genus Decreases 👪 Source Study
Brassicibacter genus Decreases 👪 Source Study
Brevifollis genus Decreases 👪 Source Study
Caldisalinibacter genus Decreases 👪 Source Study
Caloramator genus Decreases 👪 Source Study
Caminicella genus Decreases 👪 Source Study
Candidatus Arthromitus genus Decreases 👪 Source Study
Clostridiisalibacter genus Decreases 👪 Source Study
Criibacterium genus Decreases 👪 Source Study
Falcatimonas genus Decreases 👪 Source Study
Fervidicella genus Decreases 👪 Source Study
Filifactor genus Decreases 👪 Source Study
Fonticella genus Decreases 👪 Source Study
Gardnerella genus Decreases 👪 Source Study
Geosporobacter genus Decreases 👪 Source Study
Haloferula genus Decreases 👪 Source Study
Hathewaya genus Decreases 👪 Source Study
Hungatella genus Decreases 👪 Source Study
Intestinibacter genus Decreases 👪 Source Study
Lactonifactor genus Decreases 👪 Source Study
Luteolibacter genus Decreases 👪 Source Study
Lutispora genus Decreases 👪 Source Study
Maledivibacter genus Decreases 👪 Source Study
Massilioclostridium genus Decreases 👪 Source Study
Mediterranea genus Decreases 👪 Source Study
Mordavella genus Decreases 👪 Source Study
Natronincola genus Decreases 👪 Source Study
Neoscardovia genus Decreases 👪 Source Study
Oceanirhabdus genus Decreases 👪 Source Study
Oxobacter genus Decreases 👪 Source Study
Paeniclostridium genus Decreases 👪 Source Study
Paraclostridium genus Decreases 👪 Source Study
Parascardovia genus Decreases 👪 Source Study
Peptoanaerobacter genus Decreases 👪 Source Study
Peptostreptococcus genus Decreases 👪 Source Study
Persicirhabdus genus Decreases 👪 Source Study
Prosthecobacter genus Decreases 👪 Source Study
Proteocatella genus Decreases 👪 Source Study
Pseudoscardovia genus Decreases 👪 Source Study
Romboutsia genus Decreases 👪 Source Study
Roseimicrobium genus Decreases 👪 Source Study
Sarcina genus Decreases 👪 Source Study
Scardovia genus Decreases 👪 Source Study
Sporacetigenium genus Decreases 👪 Source Study
Sporosalibacterium genus Decreases 👪 Source Study
Tepidibacter genus Decreases 👪 Source Study
Terrisporobacter genus Decreases 👪 Source Study
Tindallia genus Decreases 👪 Source Study
Verrucomicrobium genus Decreases 👪 Source Study
Youngiibacter genus Decreases 👪 Source Study
Akkermansia muciniphila species Decreases 📓 Source Study
Bacteroides ovatus species Decreases 📓 Source Study
Bacteroides thetaiotaomicron species Decreases 📓 Source Study
Bacteroides xylanisolvens species Decreases 📓 Source Study
Bifidobacterium bifidum species Decreases 📓 Source Study
Bifidobacterium breve species Decreases 📓 Source Study
Clostridioides difficile species Decreases 📓 Source Study
Acuformis perennis species Decreases 👪 Source Study
Akkermansia glycaniphila species Decreases 👪 Source Study
Akkermansia sp. species Decreases 👪 Source Study
ATCC 27021 species Decreases 👪 Source Study
Bacteroides caecimuris species Decreases 👪 Source Study
Bacteroides coprosuis species Decreases 👪 Source Study
Bacteroides faecichinchillae species Decreases 👪 Source Study
Bacteroides galacturonicus species Decreases 👪 Source Study
Bacteroides heparinolyticus species Decreases 👪 Source Study
Bacteroides mediterraneensis species Decreases 👪 Source Study
Bacteroides sp. 1_1_14 species Decreases 👪 Source Study
Bacteroides sp. 1_1_30 species Decreases 👪 Source Study
Bacteroides sp. 1B2 species Decreases 👪 Source Study
Bacteroides sp. 2_1_22 species Decreases 👪 Source Study
Bacteroides sp. 2_1_33B species Decreases 👪 Source Study
Bacteroides sp. 2011_Ileo_VSA_D11 species Decreases 👪 Source Study
Bacteroides sp. 2011_Ileo_VSA_D8 species Decreases 👪 Source Study
Bacteroides sp. 265d species Decreases 👪 Source Study
Bacteroides sp. 3_1_19 species Decreases 👪 Source Study
Bacteroides sp. 3_1_33FAA species Decreases 👪 Source Study
Bacteroides sp. 3_2_5 species Decreases 👪 Source Study
Bacteroides sp. 314-4 species Decreases 👪 Source Study
Bacteroides sp. 31SF18 species Decreases 👪 Source Study
Bacteroides sp. 35BE34 species Decreases 👪 Source Study
Bacteroides sp. 35BE35 species Decreases 👪 Source Study
Bacteroides sp. 4_3_47FAA species Decreases 👪 Source Study
Bacteroides sp. 6-8 species Decreases 👪 Source Study
Bacteroides sp. 7853 species Decreases 👪 Source Study
Bacteroides sp. 9_1_42FAA species Decreases 👪 Source Study
Bacteroides sp. A1C1 species Decreases 👪 Source Study
Bacteroides sp. baku-33 species Decreases 👪 Source Study
Bacteroides sp. BLBE-2 species Decreases 👪 Source Study
Bacteroides sp. C13EG172 species Decreases 👪 Source Study
Bacteroides sp. D1 species Decreases 👪 Source Study
Bacteroides sp. D2 species Decreases 👪 Source Study
Bacteroides sp. D8 species Decreases 👪 Source Study
Bacteroides sp. dnLKV2 species Decreases 👪 Source Study
Bacteroides sp. dnLKV7 species Decreases 👪 Source Study
Bacteroides sp. ES-27 species Decreases 👪 Source Study
Bacteroides sp. HGA0134 species Decreases 👪 Source Study
Bacteroides sp. MANG species Decreases 👪 Source Study
Bacteroides sp. R6 species Decreases 👪 Source Study
Bacteroides sp. S-18 species Decreases 👪 Source Study
Bacteroides sp. Smarlab 3302398 species Decreases 👪 Source Study
Bacteroides sp. UW species Decreases 👪 Source Study
Bacteroides sp. WA1 species Decreases 👪 Source Study
Bacteroides sp. WH2 species Decreases 👪 Source Study
Bacteroides zoogleoformans species Decreases 👪 Source Study
Bifidobacterium actinocoloniiforme species Decreases 👪 Source Study
Bifidobacterium angulatum species Decreases 👪 Source Study
Bifidobacterium avesanii species Decreases 👪 Source Study
Bifidobacterium cuniculi species Decreases 👪 Source Study
Bifidobacterium lemurum species Decreases 👪 Source Study
Bifidobacterium sp. 113 species Decreases 👪 Source Study
Bifidobacterium sp. group II-3 species Decreases 👪 Source Study
Bifidobacterium sp. h12 species Decreases 👪 Source Study
Bifidobacterium sp. JCM 6439 species Decreases 👪 Source Study
Bifidobacterium sp. M45 species Decreases 👪 Source Study
Bifidobacterium sp. MC_8 species Decreases 👪 Source Study
Bifidobacterium sp. PL1 species Decreases 👪 Source Study
Candidatus Bacteroides periocalifornicus species Decreases 👪 Source Study
Clostridioides mangenotii species Decreases 👪 Source Study
Clostridium aceticum species Decreases 👪 Source Study
Clostridium acetobutylicum species Decreases 👪 Source Study
Clostridium acidisoli species Decreases 👪 Source Study
Clostridium aestuarii species Decreases 👪 Source Study
Clostridium akagii species Decreases 👪 Source Study
Clostridium algidicarnis species Decreases 👪 Source Study
Clostridium algifaecis species Decreases 👪 Source Study
Clostridium amylolyticum species Decreases 👪 Source Study
Clostridium argentinense species Decreases 👪 Source Study
Clostridium aurantibutyricum species Decreases 👪 Source Study
Clostridium autoethanogenum species Decreases 👪 Source Study
Clostridium beijerinckii species Decreases 👪 Source Study
Clostridium bornimense species Decreases 👪 Source Study
Clostridium botulinum species Decreases 👪 Source Study
Clostridium cadaveris species Decreases 👪 Source Study
Clostridium carboxidivorans species Decreases 👪 Source Study
Clostridium cavendishii species Decreases 👪 Source Study
Clostridium celatum species Decreases 👪 Source Study
Clostridium cellulovorans species Decreases 👪 Source Study
Clostridium chartatabidum species Decreases 👪 Source Study
Clostridium chauvaei species Decreases 👪 Source Study
Clostridium chromiireducens species Decreases 👪 Source Study
Clostridium cochlearium species Decreases 👪 Source Study
Clostridium colicanis species Decreases 👪 Source Study
Clostridium collagenovorans species Decreases 👪 Source Study
Clostridium cylindrosporum species Decreases 👪 Source Study
Clostridium disporicum species Decreases 👪 Source Study
Clostridium drakei species Decreases 👪 Source Study
Clostridium estertheticum species Decreases 👪 Source Study
Clostridium formicaceticum species Decreases 👪 Source Study
Clostridium frigidicarnis species Decreases 👪 Source Study
Clostridium frigoris species Decreases 👪 Source Study
Clostridium ganghwense species Decreases 👪 Source Study
Clostridium gasigenes species Decreases 👪 Source Study
Clostridium grantii species Decreases 👪 Source Study
Clostridium haemolyticum species Decreases 👪 Source Study
Clostridium hydrogeniformans species Decreases 👪 Source Study
Clostridium intestinale species Decreases 👪 Source Study
Clostridium isatidis species Decreases 👪 Source Study
Clostridium kluyveri species Decreases 👪 Source Study
Clostridium kogasensis species Decreases 👪 Source Study
Clostridium ljungdahlii species Decreases 👪 Source Study
Clostridium lundense species Decreases 👪 Source Study
Clostridium maximum species Decreases 👪 Source Study
Clostridium neonatale Bouvet et al. 2014 species Decreases 👪 Source Study
Clostridium nigeriense species Decreases 👪 Source Study
Clostridium novyi species Decreases 👪 Source Study
Clostridium oceanicum species Decreases 👪 Source Study
Clostridium oryzae species Decreases 👪 Source Study
Clostridium paraputrificum species Decreases 👪 Source Study
Clostridium pasteurianum species Decreases 👪 Source Study
Clostridium phoceensis species Decreases 👪 Source Study
Clostridium polyendosporum species Decreases 👪 Source Study
Clostridium putrefaciens species Decreases 👪 Source Study
Clostridium quinii species Decreases 👪 Source Study
Clostridium saccharobutylicum species Decreases 👪 Source Study
Clostridium sartagoforme species Decreases 👪 Source Study
Clostridium scatologenes species Decreases 👪 Source Study
Clostridium schirmacherense species Decreases 👪 Source Study
Clostridium senegalense species Decreases 👪 Source Study
Clostridium septicum species Decreases 👪 Source Study
Clostridium sp. species Decreases 👪 Source Study
Clostridium sp. 14505 species Decreases 👪 Source Study
Clostridium sp. 619 species Decreases 👪 Source Study
Clostridium sp. 7_2_43FAA species Decreases 👪 Source Study
Clostridium sp. AT32 species Decreases 👪 Source Study
Clostridium sp. AT4 species Decreases 👪 Source Study
Clostridium sp. AUH-JLC235 species Decreases 👪 Source Study
Clostridium sp. AWRP species Decreases 👪 Source Study
Clostridium sp. BNL1100 species Decreases 👪 Source Study
Clostridium sp. BPY5 species Decreases 👪 Source Study
Clostridium sp. BS-5 species Decreases 👪 Source Study
Clostridium sp. CL-2 species Decreases 👪 Source Study
Clostridium sp. Clone-17 species Decreases 👪 Source Study
Clostridium sp. Clone-24 species Decreases 👪 Source Study
Clostridium sp. Clone-49 species Decreases 👪 Source Study
Clostridium sp. CM-C81 species Decreases 👪 Source Study
Clostridium sp. CT4 species Decreases 👪 Source Study
Clostridium sp. cTPY-17 species Decreases 👪 Source Study
Clostridium sp. Culture Jar-8 species Decreases 👪 Source Study
Clostridium sp. Culture-1 species Decreases 👪 Source Study
Clostridium sp. EDB2 species Decreases 👪 Source Study
Clostridium sp. FCB45 species Decreases 👪 Source Study
Clostridium sp. FCB90-3 species Decreases 👪 Source Study
Clostridium sp. JN-1 species Decreases 👪 Source Study
Clostridium sp. JN-9 species Decreases 👪 Source Study
Clostridium sp. JN500901 species Decreases 👪 Source Study
Clostridium sp. JPL_22 species Decreases 👪 Source Study
Clostridium sp. L2-50 species Decreases 👪 Source Study
Clostridium sp. M62/1 species Decreases 👪 Source Study
Clostridium sp. Marseille-P2776 species Decreases 👪 Source Study
Clostridium sp. Marseille-P3122 species Decreases 👪 Source Study
Clostridium sp. Marseille-P3244 species Decreases 👪 Source Study
Clostridium sp. MDA2315 species Decreases 👪 Source Study
Clostridium sp. MF28 species Decreases 👪 Source Study
Clostridium sp. MLG856-1 species Decreases 👪 Source Study
Clostridium sp. MSTE9 species Decreases 👪 Source Study
Clostridium sp. NML 04A032 species Decreases 👪 Source Study
Clostridium sp. NT-1 species Decreases 👪 Source Study
Clostridium sp. P301 species Decreases 👪 Source Study
Clostridium sp. Pao32 species Decreases 👪 Source Study
Clostridium sp. PPf35E6 species Decreases 👪 Source Study
Clostridium sp. R96 species Decreases 👪 Source Study
Clostridium sp. SR1 species Decreases 👪 Source Study
Clostridium sp. SS2/1 species Decreases 👪 Source Study
Clostridium sp. SW003 species Decreases 👪 Source Study
Clostridium sp. SY8519 species Decreases 👪 Source Study
Clostridium sp. TB5 species Decreases 👪 Source Study
Clostridium sp. YIT 12069 species Decreases 👪 Source Study
Clostridium taeniosporum species Decreases 👪 Source Study
Clostridium tarantellae species Decreases 👪 Source Study
Clostridium tertium species Decreases 👪 Source Study
Clostridium tetani species Decreases 👪 Source Study
Clostridium thermobutyricum species Decreases 👪 Source Study
Clostridium thermopalmarium species Decreases 👪 Source Study
Clostridium tyrobutyricum species Decreases 👪 Source Study
Clostridium uliginosum species Decreases 👪 Source Study
Clostridium ventriculi species Decreases 👪 Source Study
Clostridium vincentii species Decreases 👪 Source Study
D5 species Decreases 👪 Source Study
environmental samples species Decreases 👪 Source Study
environmental samples species Decreases 👪 Source Study
Peptoclostridium acidaminophilum species Decreases 👪 Source Study

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This is an Academic site. It generates theoretical models of what may benefit a specific microbiome results.