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🍽️ albendazole,(prescription)

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  1. Antiparasitic Action: Albendazole is a broad-spectrum anthelmintic agent that works by interfering with the microtubule function in the cells of parasites. This leads to disruption of their metabolism, inhibition of glucose uptake, and eventual death of the parasites.

  2. Treatment of Intestinal Worm Infections: Albendazole is used in the treatment of various intestinal worm infections, including:

    • Soil-transmitted helminth infections such as roundworm (Ascaris lumbricoides), hookworm (Ancylostoma duodenale, Necator americanus), and whipworm (Trichuris trichiura).
    • Intestinal tapeworm infections such as Taenia solium (pork tapeworm) and Hymenolepis nana (dwarf tapeworm).
    • Pinworm (Enterobius vermicularis) infections.
  3. Treatment of Tissue Worm Infections: Albendazole is also used in the treatment of certain tissue worm infections, including:

    • Neurocysticercosis: Infection of the central nervous system caused by the larval stage of Taenia solium.
    • Hydatid disease: Infection caused by the larval stage of the Echinococcus tapeworm, leading to the formation of cysts in various organs such as the liver, lungs, and brain.
  4. Dosage and Administration: Albendazole is usually administered orally in the form of tablets or suspension. The dosage and duration of treatment depend on the type and severity of the infection. It is often taken with food to enhance absorption and reduce the risk of gastrointestinal side effects.

  5. Efficacy: Albendazole is highly effective against a wide range of parasitic worms, leading to clearance of the infection and resolution of symptoms in most cases. However, treatment failure or recurrence of infection may occur in some individuals, particularly in areas where reinfection is common or in cases of drug resistance.

  6. Side Effects: Common side effects of albendazole may include gastrointestinal symptoms such as abdominal pain, nausea, vomiting, diarrhea, or constipation. These side effects are usually mild and transient and may resolve with continued use. Allergic reactions such as rash or itching may occur rarely.

  7. Liver Function Monitoring: Albendazole may rarely cause hepatotoxicity (liver damage), particularly at higher doses or with prolonged use. Patients should undergo regular monitoring of liver function tests (e.g., alanine transaminase, aspartate transaminase) during treatment, especially in individuals with pre-existing liver disease.

  8. Contraindications: Albendazole is contraindicated in individuals with known hypersensitivity to the drug or its components. It should be used with caution in pregnant women, as animal studies have shown potential embryotoxic and teratogenic effects. The potential benefits of treatment should be weighed against the risks in pregnant patients.

  9. Drug Interactions: Albendazole may interact with certain medications, including cimetidine, dexamethasone, and praziquantel. Concurrent use should be monitored, and dosage adjustments may be necessary to avoid potential interactions or adverse effects.

  10. Preventive Measures: In addition to treatment with albendazole, preventive measures such as improved sanitation, hygiene practices, and deworming programs may be implemented to reduce the risk of parasitic infections, particularly in endemic areas.

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Data Contradictions β€” Limits of Certainity

Impacted of albendazole,(prescription) On Probiotics

Rank Probiotic Impact
species Akkermansia muciniphila Reduces
species Escherichia coli Reduces

Bacteria Impacted by albendazole,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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Taxonomy Rank Effect Citations Notation
Wolbachia genus Decreases 📓 Source Study
Mediterraneibacter genus Decreases 👪 Source Study
Streptococcus genus Decreases 👪 Source Study
Blautia genus Decreases 👪 Source Study
Roseburia genus Decreases 👪 Source Study
Escherichia genus Decreases 👪 Source Study
Ruminococcus genus Decreases 👪 Source Study
Akkermansia genus Decreases 👪 Source Study
Dorea genus Decreases 👪 Source Study
Lachnospira genus Decreases 👪 Source Study
unclassified Fusobacterium no rank Decreases ⚗️ Source Study
unclassified Robinsoniella no rank Decreases ⚗️ Source Study
unclassified Negativicoccus no rank Decreases ⚗️ Source Study
unclassified Wolbachia no rank Decreases 👶 Source Study
Escherichia coli O80:H26 no rank Decreases 👶 Source Study
Eggerthellales order Decreases ⚗️ Source Study
Escherichia coli O145 serogroup Decreases 👶 Source Study
Escherichia coli O157 serogroup Decreases 👶 Source Study
Escherichia coli O26 serogroup Decreases 👶 Source Study
Escherichia coli O43 serogroup Decreases 👶 Source Study
Escherichia coli O1:H42 serotype Decreases 👶 Source Study
Escherichia coli O104:H4 serotype Decreases 👶 Source Study
Escherichia coli O121:H19 serotype Decreases 👶 Source Study
Escherichia coli O127:H6 serotype Decreases 👶 Source Study
Escherichia coli O139:H28 serotype Decreases 👶 Source Study
Escherichia coli O157:H7 serotype Decreases 👶 Source Study bloody diarrhea
Escherichia coli O44:H18 serotype Decreases 👶 Source Study
Escherichia coli O55:H7 serotype Decreases 👶 Source Study
Escherichia coli O6:H16 serotype Decreases 👶 Source Study
Escherichia coli O7:K1 serotype Decreases 👶 Source Study
[Ruminococcus] torques species Decreases 📓 Source Study
Streptococcus salivarius species Decreases 📓 Source Study Infectious bacteria
Blautia obeum species Decreases 📓 Source Study
Roseburia intestinalis species Decreases 📓 Source Study
Escherichia coli species Decreases 📓 Source Study Diarrheal disease in children and travelers, Foodborne diarrhea outbreaks, hemorrhagic colitis, hemolytic-uremic syndrome
Ruminococcus bromii species Decreases 📓 Source Study
Anaerofustis stercorihominis species Decreases ⚗️ Source Study
Asaccharospora irregularis species Decreases ⚗️ Source Study
Negativicoccus sp. S5-A15 species Decreases ⚗️ Source Study
Wolbachia pipientis species Decreases 👶 Source Study
Slackia sp. NATTS species Decreases ⚗️ Source Study
Pseudoflavonifractor capillosus species Decreases ⚗️ Source Study
[Collinsella] massiliensis species Decreases ⚗️ Source Study
Allisonella histaminiformans species Decreases ⚗️ Source Study
Parvibacter caecicola species Decreases ⚗️ Source Study
Akkermansia muciniphila species Decreases 📓 Source Study
Dorea formicigenerans species Decreases 📓 Source Study
Lachnospira eligens species Decreases 📓 Source Study
Coriobacterineae suborder Decreases ⚗️ Source Study
Chlamydiae/Verrucomicrobia group superphylum Decreases ⚗️ Source Study
Wolbachieae tribe Decreases 👪 Source Study

Impact of albendazole,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
ADHD 0.7 0.7
Age-Related Macular Degeneration and Glaucoma 0.5 0.5
Allergic Rhinitis (Hay Fever) 0.2 0.2
Allergies 1.5 0.5 2
Allergy to milk products 0.7 0.2 2.5
Alopecia (Hair Loss) 0.5 0.5
Alzheimer's disease 1 2.1 -1.1
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0.4 0.8 -1
Ankylosing spondylitis 1.7 0.2 7.5
Anorexia Nervosa 1.2 -1.2
Antiphospholipid syndrome (APS) 1.9 1.9
Asthma 0.6 -0.6
Atherosclerosis 0.2 1.4 -6
Atrial fibrillation 1.2 0.2 5
Autism 2.6 2.1 0.24
Barrett esophagus cancer 0.5 -0.5
benign prostatic hyperplasia 0.2 0.2
Bipolar Disorder 0.4 0.7 -0.75
Brain Trauma 0.5 -0.5
Carcinoma 1.4 0.7 1
Celiac Disease 1 0.8 0.25
Cerebral Palsy 0.6 1.1 -0.83
Chronic Fatigue Syndrome 0.8 1.6 -1
Chronic Kidney Disease 1.2 0.5 1.4
Chronic Lyme 0.5 -0.5
Chronic Obstructive Pulmonary Disease (COPD) 1.5 0.5 2
Chronic Urticaria (Hives) 1.2 0.1 11
Coagulation / Micro clot triggering bacteria 1.2 1.6 -0.33
Colorectal Cancer 2.3 2.3
Constipation 0.2 0.9 -3.5
Coronary artery disease 0.2 0.5 -1.5
COVID-19 3 5.2 -0.73
Crohn's Disease 1.9 1.2 0.58
cystic fibrosis 0.7 0.5 0.4
deep vein thrombosis 0.7 1.1 -0.57
Depression 2.1 2 0.05
Dermatomyositis 0.5 0.5
Eczema 0.2 1.5 -6.5
Endometriosis 1.7 0.2 7.5
Epilepsy 1.3 0.6 1.17
Fibromyalgia 1 1
Functional constipation / chronic idiopathic constipation 1.8 1.5 0.2
gallstone disease (gsd) 0.9 0.5 0.8
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 1.5 -1.5
Generalized anxiety disorder 1.2 1.2
Glioblastoma 0.5 -0.5
Graves' disease 1 -1
Halitosis 0.5 -0.5
Hashimoto's thyroiditis 2 2
Hidradenitis Suppurativa 0.5 0.5
Histamine Issues,Mast Cell Issue, DAO Insufficiency 0.9 1 -0.11
hypercholesterolemia (High Cholesterol) 0.1 -0.1
hyperglycemia 0.2 0.6 -2
Hyperlipidemia (High Blood Fats) 0.1 0.1
hypersomnia 0.5 -0.5
hypertension (High Blood Pressure 1 1.5 -0.5
Hypothyroidism 0.5 -0.5
Hypoxia 0.1 0.1
IgA nephropathy (IgAN) 0 0
Inflammatory Bowel Disease 2.2 2.6 -0.18
Insomnia 1 0.5 1
Intracranial aneurysms 0.7 0.7
Irritable Bowel Syndrome 1.4 0.6 1.33
Liver Cirrhosis 1.9 1.2 0.58
Long COVID 1.3 2.6 -1
Low bone mineral density 0.5 -0.5
Lung Cancer 0.2 0.8 -3
ME/CFS with IBS 0.5 1 -1
ME/CFS without IBS 0.6 0.1 5
Metabolic Syndrome 2.4 1.8 0.33
Mood Disorders 2.4 2 0.2
multiple chemical sensitivity [MCS] 1.5 0.5 2
Multiple Sclerosis 2.4 1.2 1
Multiple system atrophy (MSA) 0.2 0.7 -2.5
Neuropathy (all types) 1 0.2 4
neuropsychiatric disorders (PANDAS, PANS) 0.5 0.5
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 1.2 1.8 -0.5
Obesity 3 1.9 0.58
obsessive-compulsive disorder 2.6 1.6 0.63
Osteoarthritis 0.7 0.2 2.5
Osteoporosis 0.4 0.6 -0.5
pancreatic cancer 0.5 0.5
Parkinson's Disease 1.1 2.8 -1.55
Polycystic ovary syndrome 0.9 0.9 0
Premenstrual dysphoric disorder 0.5 0.5
primary biliary cholangitis 0 0
Psoriasis 1.7 0.6 1.83
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 2 0.5 3
Rosacea 1.2 0.5 1.4
Schizophrenia 0.3 1.1 -2.67
scoliosis 0.2 -0.2
Sjögren syndrome 1.2 0.5 1.4
Sleep Apnea 0.7 0.9 -0.29
Small Intestinal Bacterial Overgrowth (SIBO) 1 1
Stress / posttraumatic stress disorder 1 0.6 0.67
Systemic Lupus Erythematosus 1.2 1.2 0
Tic Disorder 0.2 0.1 1
Tourette syndrome 0.1 0.1
Type 1 Diabetes 0.9 1 -0.11
Type 2 Diabetes 2.4 2.3 0.04
Ulcerative colitis 1.7 0.6 1.83
Unhealthy Ageing 1.5 0.5 2

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