Treponemataceae Details: NCBI 2845253, gram-negative or unknown [family]

1. Syphilis (Treponema pallidum):

   • Treponema pallidum is the causative agent of syphilis, a sexually transmitted infection (STI). Syphilis can progress through various stages, including primary, secondary, latent, and tertiary stages. It affects multiple organ systems and can lead to a range of symptoms, including genital sores, skin rashes, fever, and, if left untreated, more severe complications affecting the cardiovascular and nervous systems.

2. Oral Treponemes:

   • In addition to T. pallidum, other treponemes are commonly found in the oral cavity. These oral treponemes are part of the complex microbial community in the mouth and are typically associated with periodontal health and disease. Some species of oral treponemes may contribute to the development of periodontal disease.

3. Symbiotic and Saprophytic Species:

   • Many species within the genus Treponema are part of the normal microbial flora in various environments, including the digestive tracts of animals and humans. Some are commensal, living harmoniously with their host, while others are saprophytic, contributing to the decomposition of organic matter in soil and other environments.

4. Microbial Communities:

   • Treponemes are often found in complex microbial communities, where their interactions with other microorganisms and the host can influence the overall ecology and function of the community.

5. Research and Diversity:

   • The diversity within the genus Treponema is vast, and ongoing research aims to characterize and understand the various species within this group. While some species have clear pathogenic or symbiotic roles, the functions of others are still being explored.

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Treponemataceae

• Frequency - how often do samples show this bacteria
• UD - An alternative statistical algorithm (which factors in the frequency)
• Kaltoft-Moldrup Heuristic Using uploaded data
• Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)

Lab	Frequency	UD-Low	UD-High	KM Low	KM High	Lab Low	Lab High	Mean	Median	Standard Deviation	Box Plot Low	Box Plot High	KM Percentile Low	KM Percentile High
Other Labs	1.37			6	17780	0	14807	2857.2	310	6096.7	0	1090	0 %ile	100 %ile
biomesight	22.76	0	10	10	60	0	26625	1233.8	30	12954.8	10	70	0 %ile	89 %ile
thorne	100			32	178	1	155	78.3	64	39.3	40	156	0 %ile	100 %ile
thryve	5.78	0	0	9	1001	0	282	39.6	19	123.5	9	39	0 %ile	100 %ile

External Reference Ranges for Treponemataceae

Treponemataceae (NCBI 2845253) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age

Statistic by Lab Source for Treponemataceae

These desired values are reported from the lab reports

Lab	Frequency Seen	Average	Standard Deviation	Sample Count	Lab Samples
BiomeSight	23.76 %	0.096 %	1.139 %	704.0	2963
BiomeSightRdp	12.903 %	0.002 %	0.003 %	4.0	31
CerbaLab	100 %	0.042 %	0.027 %	3.0	3
custom	40.984 %	0.859 %	0.851 %	25.0	61
es-xenogene	75.862 %	0.033 %	0.019 %	22.0	29
Medivere	14.286 %	0.001 %	%	1.0	7
Thorne	68.269 %	0.005 %	0.004 %	71.0	104
Thryve	5.612 %	0.011 %	0.067 %	78.0	1390
Tiny	50 %	0.002 %	%	1.0	2

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Data Contradictions — Limits of Certainity

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General Substance	Specific Substance	Effect
Antibiotics, Antivirals etc	doxycycline (antibiotic)s[CFS]	1 Studies recorded. The consensus is Decreases👪, Click for details.
Antibiotics, Antivirals etc	erythromycin (antibiotic)s[CFS]	1 Studies recorded. The consensus is Decreases👪, Click for details.
Antibiotics, Antivirals etc	metronidazole (antibiotic)s[CFS]	1 Studies recorded. The consensus is Decreases👪, Click for details.
flavonoids, polyphenols etc	chestnut tannins	1 Studies recorded. The consensus is Increases👪, Click for details.
flavonoids, polyphenols etc	quebracho	1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings)	apple	1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings)	pectin	1 Studies recorded. The consensus is Increases👪, Click for details.
Herb or Spice	Moringa Oleifera	1 Studies recorded. The consensus is Increases👪, Click for details.
Prebiotics and similar	arabinogalactan (prebiotic)	1 Studies recorded. The consensus is Increases👪, Click for details.
Prebiotics and similar	Glucomannan	1 Studies recorded. The consensus is Increases👪, Click for details.
Prebiotics and similar	xylan (prebiotic)	1 Studies recorded. The consensus is Increases👪, Click for details.
Prescription - Other	helminth infection (prescription)	1 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics	bacillus amyloliquefaciens (probiotic)	1 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics	lactobacillus salivarius (probiotics)	1 Studies recorded. The consensus is Increases👪, Click for details.
Vitamins, Minerals and similar	fluorine	1 Studies recorded. The consensus is Decreases👪, Click for details.

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